Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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76 genes differentially expressed following the BRD-K94012289_OSI-027_SKBR3_3_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B |
APOLD1 | apolipoprotein L domain containing 1 |
BCL6 | B-cell CLL/lymphoma 6 |
CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
CFLAR | CASP8 and FADD-like apoptosis regulator |
DLK1 | delta-like 1 homolog (Drosophila) |
ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
FOXO3 | forkhead box O3 |
GNG11 | guanine nucleotide binding protein (G protein), gamma 11 |
GPNMB | glycoprotein (transmembrane) nmb |
GRB7 | growth factor receptor-bound protein 7 |
HBP1 | HMG-box transcription factor 1 |
HMGB2 | high mobility group box 2 |
HNMT | histamine N-methyltransferase |
IGFBP7 | insulin-like growth factor binding protein 7 |
IL6ST | interleukin 6 signal transducer |
IQCG | IQ motif containing G |
KIAA0355 | KIAA0355 |
KIAA1033 | KIAA1033 |
LGALS8 | lectin, galactoside-binding, soluble, 8 |
LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
MX2 | MX dynamin-like GTPase 2 |
MYC | v-myc avian myelocytomatosis viral oncogene homolog |
MYLK | myosin light chain kinase |
MYOF | myoferlin |
NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
PEG3 | paternally expressed 3 |
PSD3 | pleckstrin and Sec7 domain containing 3 |
S100A11 | S100 calcium binding protein A11 |
SH3BGRL | SH3 domain binding glutamate-rich protein like |
SRGN | serglycin |
SRPK2 | SRSF protein kinase 2 |
STC2 | stanniocalcin 2 |
SYNM | synemin, intermediate filament protein |
TFRC | transferrin receptor |
TGIF1 | TGFB-induced factor homeobox 1 |
TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
TNC | tenascin C |
TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
Symbol | Name |
---|---|
ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide |
ADIRF | adipogenesis regulatory factor |
AKR1C3 | aldo-keto reductase family 1, member C3 |
ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A |
CD69 | CD69 molecule |
CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
CLIC5 | chloride intracellular channel 5 |
COTL1 | coactosin-like F-actin binding protein 1 |
CTSH | cathepsin H |
CXCL9 | chemokine (C-X-C motif) ligand 9 |
CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
DCN | decorin |
DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
EAF2 | ELL associated factor 2 |
FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide |
FOLR1 | folate receptor 1 (adult) |
FZD7 | frizzled class receptor 7 |
G0S2 | G0/G1 switch 2 |
GATA2 | GATA binding protein 2 |
GPX3 | glutathione peroxidase 3 |
HBB | hemoglobin, beta |
HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
IDO1 | indoleamine 2,3-dioxygenase 1 |
IGHM | immunoglobulin heavy constant mu |
IGKV4-1 | immunoglobulin kappa variable 4-1 |
IGL | immunoglobulin lambda locus |
IRF8 | interferon regulatory factor 8 |
JCHAIN | joining chain of multimeric IgA and IgM |
MALL | mal, T-cell differentiation protein-like |
PEA15 | phosphoprotein enriched in astrocytes 15 |
PLAC8 | placenta-specific 8 |
PODXL | podocalyxin-like |
PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
RGCC | regulator of cell cycle |
SFTPC | surfactant protein C |
SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 |