Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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127 genes differentially expressed following the BRD-K94176593_TWS-119_HA1E_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
APLP2 | amyloid beta (A4) precursor-like protein 2 |
ASRGL1 | asparaginase like 1 |
ASS1 | argininosuccinate synthase 1 |
BRD3 | bromodomain containing 3 |
BST2 | bone marrow stromal cell antigen 2 |
C1R | complement component 1, r subcomponent |
C1RL | complement component 1, r subcomponent-like |
C3 | complement component 3 |
CADM1 | cell adhesion molecule 1 |
CCL2 | chemokine (C-C motif) ligand 2 |
CCL5 | chemokine (C-C motif) ligand 5 |
CEBPD | CCAAT/enhancer binding protein (C/EBP), delta |
COL4A5 | collagen, type IV, alpha 5 |
CTSB | cathepsin B |
CX3CL1 | chemokine (C-X3-C motif) ligand 1 |
CXADR | coxsackie virus and adenovirus receptor |
DDR1 | discoidin domain receptor tyrosine kinase 1 |
DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 |
DPP4 | dipeptidyl-peptidase 4 |
DTX4 | deltex 4, E3 ubiquitin ligase |
ECH1 | enoyl CoA hydratase 1, peroxisomal |
EPCAM | epithelial cell adhesion molecule |
FBLN1 | fibulin 1 |
FGFR2 | fibroblast growth factor receptor 2 |
FILIP1L | filamin A interacting protein 1-like |
GNAS | GNAS complex locus |
GPC1 | glypican 1 |
GPX1 | glutathione peroxidase 1 |
GSN | gelsolin |
HLA-B | major histocompatibility complex, class I, B |
HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 |
KCTD12 | potassium channel tetramerization domain containing 12 |
LAMA5 | laminin, alpha 5 |
LIPG | lipase, endothelial |
LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 |
MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
MKNK1 | MAP kinase interacting serine/threonine kinase 1 |
MMP7 | matrix metallopeptidase 7 |
MTUS1 | microtubule associated tumor suppressor 1 |
MUC1 | mucin 1, cell surface associated |
NFIB | nuclear factor I/B |
NID1 | nidogen 1 |
NR2F1 | nuclear receptor subfamily 2, group F, member 1 |
OLFM4 | olfactomedin 4 |
PFKL | phosphofructokinase, liver |
PLXNB1 | plexin B1 |
PPL | periplakin |
PROS1 | protein S (alpha) |
PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 |
RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 |
SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
SLC11A2 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 |
SLC2A4RG | SLC2A4 regulator |
SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 |
SOX4 | SRY (sex determining region Y)-box 4 |
SYNE2 | spectrin repeat containing, nuclear envelope 2 |
TMSB15A | thymosin beta 15a |
TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
TPP1 | tripeptidyl peptidase I |
ZFP36L2 | ZFP36 ring finger protein-like 2 |
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ABHD6 | abhydrolase domain containing 6 |
ACSL1 | acyl-CoA synthetase long-chain family member 1 |
ASNS | asparagine synthetase (glutamine-hydrolyzing) |
AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
CCND1 | cyclin D1 |
CD59 | CD59 molecule, complement regulatory protein |
CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain |
CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
CHRDL1 | chordin-like 1 |
CKAP4 | cytoskeleton-associated protein 4 |
CLMN | calmin (calponin-like, transmembrane) |
CRCT1 | cysteine-rich C-terminal 1 |
DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 |
DUSP2 | dual specificity phosphatase 2 |
EGR1 | early growth response 1 |
EGR3 | early growth response 3 |
EIF5A | eukaryotic translation initiation factor 5A |
EMP1 | epithelial membrane protein 1 |
EREG | epiregulin |
FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
FOSL1 | FOS-like antigen 1 |
FXYD3 | FXYD domain containing ion transport regulator 3 |
FZD7 | frizzled class receptor 7 |
G0S2 | G0/G1 switch 2 |
HBEGF | heparin-binding EGF-like growth factor |
HMGA2 | high mobility group AT-hook 2 |
HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase |
ICAM3 | intercellular adhesion molecule 3 |
IDI1 | isopentenyl-diphosphate delta isomerase 1 |
IER3 | immediate early response 3 |
IGHM | immunoglobulin heavy constant mu |
INSIG1 | insulin induced gene 1 |
KLF2 | Kruppel-like factor 2 |
LDLR | low density lipoprotein receptor |
MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
MOK | MOK protein kinase |
MREG | melanoregulin |
MSMO1 | methylsterol monooxygenase 1 |
MYC | v-myc avian myelocytomatosis viral oncogene homolog |
NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
PCOLCE2 | procollagen C-endopeptidase enhancer 2 |
PDE4DIP | phosphodiesterase 4D interacting protein |
PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
PSMD4 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 |
RCN3 | reticulocalbin 3, EF-hand calcium binding domain |
RHCG | Rh family, C glycoprotein |
SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
SERPINB13 | serpin peptidase inhibitor, clade B (ovalbumin), member 13 |
SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
SPINK5 | serine peptidase inhibitor, Kazal type 5 |
SPRY2 | sprouty homolog 2 (Drosophila) |
SQLE | squalene epoxidase |
STC1 | stanniocalcin 1 |
STC2 | stanniocalcin 2 |
TIMP3 | TIMP metallopeptidase inhibitor 3 |
TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 |
TPPP3 | tubulin polymerization-promoting protein family member 3 |
TUBB2A | tubulin, beta 2A class IIa |
UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 |
UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |