| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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72 genes differentially expressed following the BRD-K94390040_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 |
| AQP1 | aquaporin 1 (Colton blood group) |
| CBR3 | carbonyl reductase 3 |
| CCL5 | chemokine (C-C motif) ligand 5 |
| CCNG2 | cyclin G2 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CLU | clusterin |
| COMP | cartilage oligomeric matrix protein |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 |
| DAPK1 | death-associated protein kinase 1 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 |
| DHCR7 | 7-dehydrocholesterol reductase |
| EBP | emopamil binding protein (sterol isomerase) |
| FADS1 | fatty acid desaturase 1 |
| FDPS | farnesyl diphosphate synthase |
| FGFR3 | fibroblast growth factor receptor 3 |
| FHL1 | four and a half LIM domains 1 |
| GLUL | glutamate-ammonia ligase |
| GREM1 | gremlin 1, DAN family BMP antagonist |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| MAP7 | microtubule-associated protein 7 |
| MSMO1 | methylsterol monooxygenase 1 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| PMM1 | phosphomannomutase 1 |
| RGS1 | regulator of G-protein signaling 1 |
| SC5D | sterol-C5-desaturase |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SQLE | squalene epoxidase |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| TRIB3 | tribbles pseudokinase 3 |
| ZBTB20 | zinc finger and BTB domain containing 20 |
| Symbol | Name |
|---|---|
| ANPEP | alanyl (membrane) aminopeptidase |
| ANXA3 | annexin A3 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| COL13A1 | collagen, type XIII, alpha 1 |
| CTSC | cathepsin C |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DUSP6 | dual specificity phosphatase 6 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) |
| FAM3C | family with sequence similarity 3, member C |
| FOSL1 | FOS-like antigen 1 |
| GNAS | GNAS complex locus |
| HSPA1A | heat shock 70kDa protein 1A |
| ICAM1 | intercellular adhesion molecule 1 |
| IER3 | immediate early response 3 |
| IGFBP1 | insulin-like growth factor binding protein 1 |
| LEF1 | lymphoid enhancer-binding factor 1 |
| MIR22HG | MIR22 host gene |
| NOP16 | NOP16 nucleolar protein |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| RGCC | regulator of cell cycle |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| TACSTD2 | tumor-associated calcium signal transducer 2 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| THBS1 | thrombospondin 1 |
| TLR4 | toll-like receptor 4 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TMEM45A | transmembrane protein 45A |
