| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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160 genes differentially expressed following the BRD-K95435023_PHA-665752_HEPG2_24_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ACACA | acetyl-CoA carboxylase alpha |
| ACAT2 | acetyl-CoA acetyltransferase 2 |
| ACLY | ATP citrate lyase |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 |
| AHNAK | AHNAK nucleoprotein |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ALDOC | aldolase C, fructose-bisphosphate |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| ARG2 | arginase 2 |
| BLNK | B-cell linker |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like |
| CCL5 | chemokine (C-C motif) ligand 5 |
| CCND2 | cyclin D2 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CTSZ | cathepsin Z |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DHCR7 | 7-dehydrocholesterol reductase |
| EBP | emopamil binding protein (sterol isomerase) |
| EHD3 | EH-domain containing 3 |
| ELOVL6 | ELOVL fatty acid elongase 6 |
| EPS8L2 | EPS8-like 2 |
| FBN2 | fibrillin 2 |
| FGFR3 | fibroblast growth factor receptor 3 |
| GSN | gelsolin |
| GSTA1 | glutathione S-transferase alpha 1 |
| HLA-E | major histocompatibility complex, class I, E |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase |
| KLF6 | Kruppel-like factor 6 |
| KRT18 | keratin 18, type I |
| LDLR | low density lipoprotein receptor |
| LIMCH1 | LIM and calponin homology domains 1 |
| LIPA | lipase A, lysosomal acid, cholesterol esterase |
| LPIN1 | lipin 1 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| MAST4 | microtubule associated serine/threonine kinase family member 4 |
| MSMB | microseminoprotein, beta- |
| MSMO1 | methylsterol monooxygenase 1 |
| NDRG1 | N-myc downstream regulated 1 |
| NEFH | neurofilament, heavy polypeptide |
| NKX3-1 | NK3 homeobox 1 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OPTN | optineurin |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| PDGFC | platelet derived growth factor C |
| PPAP2A | phosphatidic acid phosphatase type 2A |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H |
| PRNP | prion protein |
| PYCARD | PYD and CARD domain containing |
| RAB40B | RAB40B, member RAS oncogene family |
| RDH11 | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) |
| RRBP1 | ribosome binding protein 1 |
| SC5D | sterol-C5-desaturase |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SLC22A18 | solute carrier family 22, member 18 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SLC39A6 | solute carrier family 39 (zinc transporter), member 6 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 |
| SPAG4 | sperm associated antigen 4 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 |
| STC1 | stanniocalcin 1 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TFF1 | trefoil factor 1 |
| TMEM97 | transmembrane protein 97 |
| TPM2 | tropomyosin 2 (beta) |
| TSC22D3 | TSC22 domain family, member 3 |
| TSPAN1 | tetraspanin 1 |
| VLDLR | very low density lipoprotein receptor |
| VNN1 | vanin 1 |
| WFDC1 | WAP four-disulfide core domain 1 |
| YPEL5 | yippee-like 5 (Drosophila) |
| ZSCAN18 | zinc finger and SCAN domain containing 18 |
| Symbol | Name |
|---|---|
| ABCE1 | ATP-binding cassette, sub-family E (OABP), member 1 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) |
| AURKA | aurora kinase A |
| BCHE | butyrylcholinesterase |
| BIRC5 | baculoviral IAP repeat containing 5 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| CA2 | carbonic anhydrase II |
| CALR | calreticulin |
| CCNA2 | cyclin A2 |
| CCNB2 | cyclin B2 |
| CDC20 | cell division cycle 20 |
| CDK1 | cyclin-dependent kinase 1 |
| CDKN3 | cyclin-dependent kinase inhibitor 3 |
| CENPA | centromere protein A |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CIAPIN1 | cytokine induced apoptosis inhibitor 1 |
| COL1A2 | collagen, type I, alpha 2 |
| COL3A1 | collagen, type III, alpha 1 |
| CP | ceruloplasmin (ferroxidase) |
| CPE | carboxypeptidase E |
| CPVL | carboxypeptidase, vitellogenic-like |
| CXCL14 | chemokine (C-X-C motif) ligand 14 |
| DBF4 | DBF4 zinc finger |
| DCN | decorin |
| DDX39A | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A |
| DEPDC1 | DEP domain containing 1 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 |
| DUSP6 | dual specificity phosphatase 6 |
| EIF5A | eukaryotic translation initiation factor 5A |
| ELANE | elastase, neutrophil expressed |
| EREG | epiregulin |
| FCGBP | Fc fragment of IgG binding protein |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) |
| H2AFV | H2A histone family, member V |
| H2AFX | H2A histone family, member X |
| HMGB2 | high mobility group box 2 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) |
| HRH1 | histamine receptor H1 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IGL | immunoglobulin lambda locus |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 |
| KIAA0101 | KIAA0101 |
| KIF20A | kinesin family member 20A |
| KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) |
| LUM | lumican |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) |
| MCM2 | minichromosome maintenance complex component 2 |
| MCM4 | minichromosome maintenance complex component 4 |
| MSLN | mesothelin |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) |
| NUSAP1 | nucleolar and spindle associated protein 1 |
| ODC1 | ornithine decarboxylase 1 |
| OXA1L | oxidase (cytochrome c) assembly 1-like |
| PBK | PDZ binding kinase |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PLK1 | polo-like kinase 1 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit |
| POLE3 | polymerase (DNA directed), epsilon 3, accessory subunit |
| PON3 | paraoxonase 3 |
| PRC1 | protein regulator of cytokinesis 1 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
| PTTG1 | pituitary tumor-transforming 1 |
| RBP1 | retinol binding protein 1, cellular |
| RFC3 | replication factor C (activator 1) 3, 38kDa |
| RGS5 | regulator of G-protein signaling 5 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) |
| RRM2 | ribonucleotide reductase M2 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 |
| SCG2 | secretogranin II |
| SCG5 | secretogranin V |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SMAD1 | SMAD family member 1 |
| SMC4 | structural maintenance of chromosomes 4 |
| SRM | spermidine synthase |
| TNC | tenascin C |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa |
| TPX2 | TPX2, microtubule-associated |
| UBE2C | ubiquitin-conjugating enzyme E2C |
| YKT6 | YKT6 v-SNARE homolog (S. cerevisiae) |
| ZWINT | ZW10 interacting kinetochore protein |
