Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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72 genes differentially expressed following the BRD-K95655893_VEGF Receptor 3 Kinase Inhibitor, MAZ51_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ADGRG2 | adhesion G protein-coupled receptor G2 |
ALG8 | ALG8, alpha-1,3-glucosyltransferase |
CA12 | carbonic anhydrase XII |
CD36 | CD36 molecule (thrombospondin receptor) |
CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
COCH | cochlin |
CSRP2 | cysteine and glycine-rich protein 2 |
FBL | fibrillarin |
FRY | furry homolog (Drosophila) |
GAB2 | GRB2-associated binding protein 2 |
HOOK2 | hook microtubule-tethering protein 2 |
HSPA1A | heat shock 70kDa protein 1A |
NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 |
NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 |
ODC1 | ornithine decarboxylase 1 |
PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 |
PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
PRDX2 | peroxiredoxin 2 |
RGS5 | regulator of G-protein signaling 5 |
SCGB2A2 | secretoglobin, family 2A, member 2 |
SLC39A6 | solute carrier family 39 (zinc transporter), member 6 |
STC2 | stanniocalcin 2 |
STEAP1 | six transmembrane epithelial antigen of the prostate 1 |
TFPI2 | tissue factor pathway inhibitor 2 |
TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
TPBG | trophoblast glycoprotein |
VWF | von Willebrand factor |
XIST | X inactive specific transcript (non-protein coding) |
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D |
CCNE2 | cyclin E2 |
CD1B | CD1b molecule |
CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
CHGB | chromogranin B |
CTSB | cathepsin B |
CTSS | cathepsin S |
CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 |
CYTL1 | cytokine-like 1 |
FN1 | fibronectin 1 |
FOLR1 | folate receptor 1 (adult) |
HEPH | hephaestin |
HIGD1A | HIG1 hypoxia inducible domain family, member 1A |
HOPX | HOP homeobox |
HPRT1 | hypoxanthine phosphoribosyltransferase 1 |
IGL | immunoglobulin lambda locus |
INHBA | inhibin, beta A |
LUM | lumican |
MAGEA3 | melanoma antigen family A3 |
MCM6 | minichromosome maintenance complex component 6 |
MFAP5 | microfibrillar associated protein 5 |
MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 |
MUC5B | mucin 5B, oligomeric mucus/gel-forming |
NNMT | nicotinamide N-methyltransferase |
OAT | ornithine aminotransferase |
PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
PDLIM3 | PDZ and LIM domain 3 |
PRDX3 | peroxiredoxin 3 |
PRPS2 | phosphoribosyl pyrophosphate synthetase 2 |
PSD3 | pleckstrin and Sec7 domain containing 3 |
PSPH | phosphoserine phosphatase |
RFTN1 | raftlin, lipid raft linker 1 |
S100P | S100 calcium binding protein P |
SAT1 | spermidine/spermine N1-acetyltransferase 1 |
SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
SNAP25 | synaptosomal-associated protein, 25kDa |
SULF1 | sulfatase 1 |
TCTA | T-cell leukemia translocation altered |
TRD | T cell receptor delta locus |
TRDV3 | T cell receptor delta variable 3 |