BRD-K95760042_2512-0754_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

64 genes differentially expressed following the BRD-K95760042_2512-0754_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALB albumin
ALOX5 arachidonate 5-lipoxygenase
ARMCX2 armadillo repeat containing, X-linked 2
BHLHE41 basic helix-loop-helix family, member e41
CCL20 chemokine (C-C motif) ligand 20
CCR7 chemokine (C-C motif) receptor 7
CLC Charcot-Leyden crystal galectin
CRABP1 cellular retinoic acid binding protein 1
CXCL11 chemokine (C-X-C motif) ligand 11
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DEFA4 defensin, alpha 4, corticostatin
DFNA5 deafness, autosomal dominant 5
DKK3 dickkopf WNT signaling pathway inhibitor 3
DLK1 delta-like 1 homolog (Drosophila)
DTX4 deltex 4, E3 ubiquitin ligase
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FGB fibrinogen beta chain
FGG fibrinogen gamma chain
GAGE3 G antigen 3
HES1 hes family bHLH transcription factor 1
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGL immunoglobulin lambda locus
IL7R interleukin 7 receptor
JCHAIN joining chain of multimeric IgA and IgM
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NTS neurotensin
PDE4B phosphodiesterase 4B, cAMP-specific
PEG10 paternally expressed 10
PRAME preferentially expressed antigen in melanoma
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
PSD3 pleckstrin and Sec7 domain containing 3
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
SCGB1D2 secretoglobin, family 1D, member 2
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SRGN serglycin
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VTCN1 V-set domain containing T cell activation inhibitor 1

decreased expression

Symbol Name
AGR2 anterior gradient 2
C1S complement component 1, s subcomponent
COL3A1 collagen, type III, alpha 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EFNB2 ephrin-B2
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EVL Enah/Vasp-like
FAM46A family with sequence similarity 46, member A
HOOK2 hook microtubule-tethering protein 2
IFITM3 interferon induced transmembrane protein 3
MAP7 microtubule-associated protein 7
NR2F2 nuclear receptor subfamily 2, group F, member 2
PHACTR2 phosphatase and actin regulator 2
PODXL podocalyxin-like
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SLC39A6 solute carrier family 39 (zinc transporter), member 6
TARBP1 TAR (HIV-1) RNA binding protein 1
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TFF1 trefoil factor 1
TSPAN13 tetraspanin 13
UBE2S ubiquitin-conjugating enzyme E2S
Funding