BRD-K95785537_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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71 genes differentially expressed following the BRD-K95785537_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
APOD apolipoprotein D
ASPH aspartate beta-hydroxylase
BTG1 B-cell translocation gene 1, anti-proliferative
C16ORF45 chromosome 16 open reading frame 45
CPD carboxypeptidase D
CREB3L2 cAMP responsive element binding protein 3-like 2
CRISP3 cysteine-rich secretory protein 3
DUSP6 dual specificity phosphatase 6
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EGR1 early growth response 1
FABP4 fatty acid binding protein 4, adipocyte
FGG fibrinogen gamma chain
FSD1 fibronectin type III and SPRY domain containing 1
GPM6B glycoprotein M6B
GPX3 glutathione peroxidase 3
HIST1H4C histone cluster 1, H4c
HOXA5 homeobox A5
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
ICAM1 intercellular adhesion molecule 1
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KRT18 keratin 18, type I
LPL lipoprotein lipase
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MT1X metallothionein 1X
NR4A2 nuclear receptor subfamily 4, group A, member 2
NRIP1 nuclear receptor interacting protein 1
OPN3 opsin 3
SFRP1 secreted frizzled-related protein 1
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SPATS2L spermatogenesis associated, serine-rich 2-like
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
TF transferrin
TFPI2 tissue factor pathway inhibitor 2
TIMP3 TIMP metallopeptidase inhibitor 3
TMEM45A transmembrane protein 45A

decreased expression

Symbol Name
ACAA2 acetyl-CoA acyltransferase 2
ADD3 adducin 3 (gamma)
ADM adrenomedullin
ADRB2 adrenoceptor beta 2, surface
AMIGO2 adhesion molecule with Ig-like domain 2
CCL5 chemokine (C-C motif) ligand 5
DPYSL3 dihydropyrimidinase-like 3
EMX2 empty spiracles homeobox 2
ERBB4 erb-b2 receptor tyrosine kinase 4
FTH1 ferritin, heavy polypeptide 1
FZD7 frizzled class receptor 7
GAB2 GRB2-associated binding protein 2
GATA3 GATA binding protein 3
HMOX1 heme oxygenase 1
HTRA1 HtrA serine peptidase 1
IL32 interleukin 32
ITM2A integral membrane protein 2A
KCTD12 potassium channel tetramerization domain containing 12
MN1 meningioma (disrupted in balanced translocation) 1
NREP neuronal regeneration related protein
NRG1 neuregulin 1
OXTR oxytocin receptor
PDE10A phosphodiesterase 10A
PDGFC platelet derived growth factor C
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
RALGDS ral guanine nucleotide dissociation stimulator
RBP1 retinol binding protein 1, cellular
SCG5 secretogranin V
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SPRR1A small proline-rich protein 1A
TRIM22 tripartite motif containing 22
VCAM1 vascular cell adhesion molecule 1
ZSCAN18 zinc finger and SCAN domain containing 18