BRD-K95785537_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

68 genes differentially expressed following the BRD-K95785537_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGR2 anterior gradient 2
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
AQP3 aquaporin 3 (Gill blood group)
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BASP1 brain abundant, membrane attached signal protein 1
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCL5 chemokine (C-C motif) ligand 5
CD24 CD24 molecule
CD9 CD9 molecule
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CERS6 ceramide synthase 6
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CRYM crystallin, mu
CXCR4 chemokine (C-X-C motif) receptor 4
DDR1 discoidin domain receptor tyrosine kinase 1
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DUSP4 dual specificity phosphatase 4
ERBB2 erb-b2 receptor tyrosine kinase 2
GPX2 glutathione peroxidase 2
HBE1 hemoglobin, epsilon 1
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
IER3 immediate early response 3
IGFBP3 insulin-like growth factor binding protein 3
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
ITGB5 integrin, beta 5
KAZN kazrin, periplakin interacting protein
KRT18 keratin 18, type I
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
NPTX2 neuronal pentraxin II
PPAP2B phosphatidic acid phosphatase type 2B
RAP1GAP RAP1 GTPase activating protein
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
S100P S100 calcium binding protein P
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SCPEP1 serine carboxypeptidase 1
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SRGN serglycin
SYT1 synaptotagmin I
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TGM2 transglutaminase 2
TXNIP thioredoxin interacting protein
UGCG UDP-glucose ceramide glucosyltransferase
ZMYND8 zinc finger, MYND-type containing 8

decreased expression

Symbol Name
ADM adrenomedullin
AK1 adenylate kinase 1
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ATF5 activating transcription factor 5
BCAT1 branched chain amino-acid transaminase 1, cytosolic
CKS2 CDC28 protein kinase regulatory subunit 2
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DLC1 DLC1 Rho GTPase activating protein
EXOSC4 exosome component 4
FABP5 fatty acid binding protein 5 (psoriasis-associated)
GABPB1 GA binding protein transcription factor, beta subunit 1
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
HOXC6 homeobox C6
KCTD12 potassium channel tetramerization domain containing 12
PXDN peroxidasin
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
S100A10 S100 calcium binding protein A10
SET SET nuclear proto-oncogene
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
TYRP1 tyrosinase-related protein 1
Funding