BRD-K95842463_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

57 genes differentially expressed following the BRD-K95842463_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADIRF adipogenesis regulatory factor
ARG2 arginase 2
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
BMP4 bone morphogenetic protein 4
CD24 CD24 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CFD complement factor D (adipsin)
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CPE carboxypeptidase E
CTBP2 C-terminal binding protein 2
CTNND1 catenin (cadherin-associated protein), delta 1
DENND1B DENN/MADD domain containing 1B
DTX4 deltex 4, E3 ubiquitin ligase
ELANE elastase, neutrophil expressed
EPAS1 endothelial PAS domain protein 1
FGFR2 fibroblast growth factor receptor 2
FTH1 ferritin, heavy polypeptide 1
GSN gelsolin
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
JCHAIN joining chain of multimeric IgA and IgM
LOC100505650 uncharacterized LOC100505650
MAN1A1 mannosidase, alpha, class 1A, member 1
MEST mesoderm specific transcript
MME membrane metallo-endopeptidase
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
MSLN mesothelin
NARFL nuclear prelamin A recognition factor-like
OLFM4 olfactomedin 4
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PON3 paraoxonase 3
PSD3 pleckstrin and Sec7 domain containing 3
RGCC regulator of cell cycle
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TRIM2 tripartite motif containing 2
VAMP8 vesicle-associated membrane protein 8

decreased expression

Symbol Name
CD59 CD59 molecule, complement regulatory protein
CHL1 cell adhesion molecule L1-like
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FSTL1 follistatin-like 1
KIAA0125 KIAA0125
LAPTM4B lysosomal protein transmembrane 4 beta
LIPG lipase, endothelial
LPL lipoprotein lipase
LY6D lymphocyte antigen 6 complex, locus D
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
PI3 peptidase inhibitor 3, skin-derived
RBP1 retinol binding protein 1, cellular
REEP5 receptor accessory protein 5
RPL36 ribosomal protein L36
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SPRR2B small proline-rich protein 2B
TFF1 trefoil factor 1
TFF3 trefoil factor 3 (intestinal)
TNC tenascin C