BRD-K95921201_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

51 genes differentially expressed following the BRD-K95921201_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CFB complement factor B
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLDN3 claudin 3
COL9A3 collagen, type IX, alpha 3
CTH cystathionine gamma-lyase
DDIT4 DNA-damage-inducible transcript 4
ETV1 ets variant 1
GDF15 growth differentiation factor 15
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA2 heat shock 70kDa protein 2
HSPA6 heat shock 70kDa protein 6 (HSP70B')
INSIG1 insulin induced gene 1
MAP7 microtubule-associated protein 7
MSMO1 methylsterol monooxygenase 1
NID2 nidogen 2 (osteonidogen)
QPRT quinolinate phosphoribosyltransferase
RHOBTB3 Rho-related BTB domain containing 3
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SGK1 serum/glucocorticoid regulated kinase 1
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3

decreased expression

Symbol Name
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ANXA1 annexin A1
CD9 CD9 molecule
CNN3 calponin 3, acidic
COL3A1 collagen, type III, alpha 1
COL4A5 collagen, type IV, alpha 5
COL5A2 collagen, type V, alpha 2
CRYAB crystallin, alpha B
CTSZ cathepsin Z
DKK1 dickkopf WNT signaling pathway inhibitor 1
KRT13 keratin 13, type I
KRT4 keratin 4, type II
KRT5 keratin 5, type II
MMP9 matrix metallopeptidase 9
PROSC proline synthetase co-transcribed homolog (bacterial)
PTN pleiotrophin
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
S100A2 S100 calcium binding protein A2
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SEPP1 selenoprotein P, plasma, 1
SLC35F2 solute carrier family 35, member F2
SPDEF SAM pointed domain containing ETS transcription factor
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STON1 stonin 1
TMEM14A transmembrane protein 14A