BRD-K95976153_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

49 genes differentially expressed following the BRD-K95976153_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACSL3 acyl-CoA synthetase long-chain family member 3
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF3 activating transcription factor 3
BZW2 basic leucine zipper and W2 domains 2
CDK2AP2 cyclin-dependent kinase 2 associated protein 2
CELF2 CUGBP, Elav-like family member 2
CETN2 centrin, EF-hand protein, 2
CKAP4 cytoskeleton-associated protein 4
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DHCR7 7-dehydrocholesterol reductase
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
ETV1 ets variant 1
FADS1 fatty acid desaturase 1
FADS2 fatty acid desaturase 2
FDPS farnesyl diphosphate synthase
FHL1 four and a half LIM domains 1
GLRX glutaredoxin (thioltransferase)
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
LTF lactotransferrin
MANF mesencephalic astrocyte-derived neurotrophic factor
MSMO1 methylsterol monooxygenase 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NSDHL NAD(P) dependent steroid dehydrogenase-like
NUPR1 nuclear protein, transcriptional regulator, 1
PDIA5 protein disulfide isomerase family A, member 5
PPAP2B phosphatidic acid phosphatase type 2B
SDF2L1 stromal cell-derived factor 2-like 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SQLE squalene epoxidase
TIMP3 TIMP metallopeptidase inhibitor 3
TRIB3 tribbles pseudokinase 3
TSC22D3 TSC22 domain family, member 3
VCAN versican
WIPI1 WD repeat domain, phosphoinositide interacting 1

decreased expression

Symbol Name
CXCL12 chemokine (C-X-C motif) ligand 12
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
INA internexin neuronal intermediate filament protein, alpha
MRPS2 mitochondrial ribosomal protein S2
MYRF myelin regulatory factor
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RRAS2 related RAS viral (r-ras) oncogene homolog 2
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
Funding