BRD-K96704648_-666_A549_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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77 genes differentially expressed following the BRD-K96704648_-666_A549_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRF5 adhesion G protein-coupled receptor F5
ADIRF adipogenesis regulatory factor
APOD apolipoprotein D
ARG2 arginase 2
BAX BCL2-associated X protein
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BTG3 BTG family, member 3
CA12 carbonic anhydrase XII
CD200 CD200 molecule
CDC42 cell division cycle 42
CLDN3 claudin 3
COL9A3 collagen, type IX, alpha 3
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
DDIT4 DNA-damage-inducible transcript 4
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DUSP4 dual specificity phosphatase 4
EFS embryonal Fyn-associated substrate
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
GPATCH8 G patch domain containing 8
H3F3B H3 histone, family 3B (H3.3B)
KDM5D lysine (K)-specific demethylase 5D
MCAM melanoma cell adhesion molecule
MGP matrix Gla protein
MMP12 matrix metallopeptidase 12
NES nestin
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PDGFD platelet derived growth factor D
PHYH phytanoyl-CoA 2-hydroxylase
PLIN2 perilipin 2
PPP1R16B protein phosphatase 1, regulatory subunit 16B
PROM1 prominin 1
PTGIS prostaglandin I2 (prostacyclin) synthase
RGS2 regulator of G-protein signaling 2
RGS5 regulator of G-protein signaling 5
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SCGB2A2 secretoglobin, family 2A, member 2
SFN stratifin
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SULF1 sulfatase 1
TCF4 transcription factor 4
TCTA T-cell leukemia translocation altered
TIMP3 TIMP metallopeptidase inhibitor 3
TLR4 toll-like receptor 4

decreased expression

Symbol Name
ATF5 activating transcription factor 5
BID BH3 interacting domain death agonist
CADM1 cell adhesion molecule 1
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CD163 CD163 molecule
CSF1R colony stimulating factor 1 receptor
CST3 cystatin C
EIF5A eukaryotic translation initiation factor 5A
EIF5B eukaryotic translation initiation factor 5B
FAM129A family with sequence similarity 129, member A
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMOX1 heme oxygenase 1
HN1 hematological and neurological expressed 1
HSPA1A heat shock 70kDa protein 1A
LDLR low density lipoprotein receptor
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
NRIP3 nuclear receptor interacting protein 3
NUP85 nucleoporin 85kDa
NXT2 nuclear transport factor 2-like export factor 2
PHKA1 phosphorylase kinase, alpha 1 (muscle)
PPIF peptidylprolyl isomerase F
PTPRO protein tyrosine phosphatase, receptor type, O
RALB v-ral simian leukemia viral oncogene homolog B
RUNX1 runt-related transcription factor 1
SMC1A structural maintenance of chromosomes 1A
SRSF1 serine/arginine-rich splicing factor 1
TRAM2 translocation associated membrane protein 2
XIST X inactive specific transcript (non-protein coding)