BRD-K96809896_-666_A549_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

88 genes differentially expressed following the BRD-K96809896_-666_A549_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACSL1 acyl-CoA synthetase long-chain family member 1
AREG amphiregulin
ASS1 argininosuccinate synthase 1
C3 complement component 3
CALD1 caldesmon 1
COL11A1 collagen, type XI, alpha 1
COL5A1 collagen, type V, alpha 1
DSP desmoplakin
EGFL6 EGF-like-domain, multiple 6
FBLN1 fibulin 1
FGG fibrinogen gamma chain
FOLR1 folate receptor 1 (adult)
FTH1 ferritin, heavy polypeptide 1
KRT17 keratin 17, type I
LOX lysyl oxidase
LTF lactotransferrin
METTL7A methyltransferase like 7A
MFAP5 microfibrillar associated protein 5
MME membrane metallo-endopeptidase
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NINJ1 ninjurin 1
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PRKCD protein kinase C, delta
RGS1 regulator of G-protein signaling 1
S100A8 S100 calcium binding protein A8
SCPEP1 serine carboxypeptidase 1
SFRP4 secreted frizzled-related protein 4
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TPP1 tripeptidyl peptidase I
TSC22D3 TSC22 domain family, member 3
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)

decreased expression

Symbol Name
ADGRG1 adhesion G protein-coupled receptor G1
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
AXL AXL receptor tyrosine kinase
C3ORF14 chromosome 3 open reading frame 14
CANT1 calcium activated nucleotidase 1
CASP7 caspase 7, apoptosis-related cysteine peptidase
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CLTB clathrin, light chain B
CST3 cystatin C
CXCL5 chemokine (C-X-C motif) ligand 5
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
DHRS2 dehydrogenase/reductase (SDR family) member 2
DOCK4 dedicator of cytokinesis 4
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FABP7 fatty acid binding protein 7, brain
FBXO21 F-box protein 21
GSTA4 glutathione S-transferase alpha 4
HES1 hes family bHLH transcription factor 1
ICAM2 intercellular adhesion molecule 2
IER3 immediate early response 3
IFI27 interferon, alpha-inducible protein 27
IFI44L interferon-induced protein 44-like
IGFBP3 insulin-like growth factor binding protein 3
IGFBP7 insulin-like growth factor binding protein 7
IL13RA2 interleukin 13 receptor, alpha 2
ISG15 ISG15 ubiquitin-like modifier
ISOC1 isochorismatase domain containing 1
JAG1 jagged 1
LGALS1 lectin, galactoside-binding, soluble, 1
LYZ lysozyme
MACF1 microtubule-actin crosslinking factor 1
MAP7 microtubule-associated protein 7
MMP7 matrix metallopeptidase 7
MRPS2 mitochondrial ribosomal protein S2
NFIB nuclear factor I/B
PALLD palladin, cytoskeletal associated protein
PAWR PRKC, apoptosis, WT1, regulator
PDLIM5 PDZ and LIM domain 5
PROM1 prominin 1
RAI14 retinoic acid induced 14
RFC2 replication factor C (activator 1) 2, 40kDa
RFK riboflavin kinase
RHOB ras homolog family member B
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SPRY2 sprouty homolog 2 (Drosophila)
TGFBI transforming growth factor, beta-induced, 68kDa
TM4SF1 transmembrane 4 L six family member 1
TMEM158 transmembrane protein 158 (gene/pseudogene)
TSPAN7 tetraspanin 7
TSPAN8 tetraspanin 8
TUBA1A tubulin, alpha 1a
TUBB2A tubulin, beta 2A class IIa
UBE2S ubiquitin-conjugating enzyme E2S
Funding