Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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63 genes differentially expressed following the BRD-K97056771_HY-11007_A375_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ACKR3 | atypical chemokine receptor 3 |
BPHL | biphenyl hydrolase-like (serine hydrolase) |
CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
CLDN3 | claudin 3 |
CYFIP2 | cytoplasmic FMR1 interacting protein 2 |
DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
EMX2 | empty spiracles homeobox 2 |
HOOK2 | hook microtubule-tethering protein 2 |
IFRD2 | interferon-related developmental regulator 2 |
IGHM | immunoglobulin heavy constant mu |
LRMP | lymphoid-restricted membrane protein |
LY6E | lymphocyte antigen 6 complex, locus E |
MTUS1 | microtubule associated tumor suppressor 1 |
PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
PDGFD | platelet derived growth factor D |
PTGIS | prostaglandin I2 (prostacyclin) synthase |
RGS2 | regulator of G-protein signaling 2 |
SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 |
SST | somatostatin |
SULF1 | sulfatase 1 |
TIMP2 | TIMP metallopeptidase inhibitor 2 |
TIMP3 | TIMP metallopeptidase inhibitor 3 |
TRAPPC6A | trafficking protein particle complex 6A |
YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon |
Symbol | Name |
---|---|
ANXA1 | annexin A1 |
ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
BEX1 | brain expressed, X-linked 1 |
CA12 | carbonic anhydrase XII |
CCND2 | cyclin D2 |
CD44 | CD44 molecule (Indian blood group) |
CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
CHPT1 | choline phosphotransferase 1 |
CLEC11A | C-type lectin domain family 11, member A |
COBL | cordon-bleu WH2 repeat protein |
CTGF | connective tissue growth factor |
CXCL8 | chemokine (C-X-C motif) ligand 8 |
DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 |
F13A1 | coagulation factor XIII, A1 polypeptide |
FABP7 | fatty acid binding protein 7, brain |
GABRP | gamma-aminobutyric acid (GABA) A receptor, pi |
GOLGA8B | golgin A8 family, member B |
GPRC5A | G protein-coupled receptor, class C, group 5, member A |
ISG20 | interferon stimulated exonuclease gene 20kDa |
ISOC1 | isochorismatase domain containing 1 |
ITM2A | integral membrane protein 2A |
LCN2 | lipocalin 2 |
LMO4 | LIM domain only 4 |
MAN1A1 | mannosidase, alpha, class 1A, member 1 |
NFIB | nuclear factor I/B |
PEX11A | peroxisomal biogenesis factor 11 alpha |
PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
PTCH1 | patched 1 |
SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
SFRP1 | secreted frizzled-related protein 1 |
SLPI | secretory leukocyte peptidase inhibitor |
TACSTD2 | tumor-associated calcium signal transducer 2 |
TM4SF1 | transmembrane 4 L six family member 1 |
TM9SF3 | transmembrane 9 superfamily member 3 |
TMEM158 | transmembrane protein 158 (gene/pseudogene) |
TMEM2 | transmembrane protein 2 |
WNT5A | wingless-type MMTV integration site family, member 5A |