BRD-K97399794_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

69 genes differentially expressed following the BRD-K97399794_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
BTG1 B-cell translocation gene 1, anti-proliferative
CAV1 caveolin 1, caveolae protein, 22kDa
CD1A CD1a molecule
CD1C CD1c molecule
CD24 CD24 molecule
CHMP4A charged multivesicular body protein 4A
COMP cartilage oligomeric matrix protein
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DEPTOR DEP domain containing MTOR-interacting protein
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FOSL1 FOS-like antigen 1
FRZB frizzled-related protein
HMOX1 heme oxygenase 1
IL13RA1 interleukin 13 receptor, alpha 1
IL1R2 interleukin 1 receptor, type II
IQGAP1 IQ motif containing GTPase activating protein 1
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
MAT2A methionine adenosyltransferase II, alpha
MMP7 matrix metallopeptidase 7
MYC v-myc avian myelocytomatosis viral oncogene homolog
NDRG1 N-myc downstream regulated 1
NEBL nebulette
NPTX2 neuronal pentraxin II
NQO1 NAD(P)H dehydrogenase, quinone 1
PPAP2B phosphatidic acid phosphatase type 2B
PROM1 prominin 1
PTGES prostaglandin E synthase
RAP1GAP RAP1 GTPase activating protein
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RNF167 ring finger protein 167
SAMD4A sterile alpha motif domain containing 4A
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLCO4A1 solute carrier organic anion transporter family, member 4A1
SOX9 SRY (sex determining region Y)-box 9
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TPD52 tumor protein D52
TTC3 tetratricopeptide repeat domain 3
TXNIP thioredoxin interacting protein
VEGFA vascular endothelial growth factor A
ZW10 zw10 kinetochore protein

decreased expression

Symbol Name
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADI1 acireductone dioxygenase 1
ARID4B AT rich interactive domain 4B (RBP1-like)
ATF5 activating transcription factor 5
BCHE butyrylcholinesterase
BID BH3 interacting domain death agonist
CSRP1 cysteine and glycine-rich protein 1
CXCL12 chemokine (C-X-C motif) ligand 12
GCH1 GTP cyclohydrolase 1
GDE1 glycerophosphodiester phosphodiesterase 1
GNG11 guanine nucleotide binding protein (G protein), gamma 11
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGL immunoglobulin lambda locus
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
INSIG1 insulin induced gene 1
ITM2A integral membrane protein 2A
KRT18 keratin 18, type I
LAPTM4B lysosomal protein transmembrane 4 beta
LMO2 LIM domain only 2 (rhombotin-like 1)
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
NCAPD2 non-SMC condensin I complex, subunit D2
TLR4 toll-like receptor 4
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRIM22 tripartite motif containing 22
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