| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
| Downloads & Tools |
94 genes differentially expressed following the BRD-K97534490_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| ATF3 | activating transcription factor 3 |
| CD24 | CD24 molecule |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CHIC2 | cysteine-rich hydrophobic domain 2 |
| CLC | Charcot-Leyden crystal galectin |
| CRCT1 | cysteine-rich C-terminal 1 |
| CSTA | cystatin A (stefin A) |
| DDIT4 | DNA-damage-inducible transcript 4 |
| EGR1 | early growth response 1 |
| EREG | epiregulin |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 |
| FABP4 | fatty acid binding protein 4, adipocyte |
| FOSL1 | FOS-like antigen 1 |
| G0S2 | G0/G1 switch 2 |
| HES1 | hes family bHLH transcription factor 1 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
| IER2 | immediate early response 2 |
| IER3 | immediate early response 3 |
| JUN | jun proto-oncogene |
| KLF10 | Kruppel-like factor 10 |
| KLF6 | Kruppel-like factor 6 |
| KRT16 | keratin 16, type I |
| KRT23 | keratin 23, type I |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MALL | mal, T-cell differentiation protein-like |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MT1E | metallothionein 1E |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) |
| RBP1 | retinol binding protein 1, cellular |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SFN | stratifin |
| SMAD3 | SMAD family member 3 |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SPRR1A | small proline-rich protein 1A |
| SPRR1B | small proline-rich protein 1B |
| SST | somatostatin |
| TACSTD2 | tumor-associated calcium signal transducer 2 |
| TFPI2 | tissue factor pathway inhibitor 2 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
| TRIB1 | tribbles pseudokinase 1 |
| TRIB3 | tribbles pseudokinase 3 |
| TUBB2A | tubulin, beta 2A class IIa |
| UPP1 | uridine phosphorylase 1 |
| VAT1 | vesicle amine transport 1 |
| ZFP36 | ZFP36 ring finger protein |
| Symbol | Name |
|---|---|
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ASS1 | argininosuccinate synthase 1 |
| BAMBI | BMP and activin membrane-bound inhibitor |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| CCND2 | cyclin D2 |
| CD99 | CD99 molecule |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| DACH1 | dachshund family transcription factor 1 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| FTH1 | ferritin, heavy polypeptide 1 |
| GATA3 | GATA binding protein 3 |
| GSTM3 | glutathione S-transferase mu 3 (brain) |
| HEG1 | heart development protein with EGF-like domains 1 |
| HMOX1 | heme oxygenase 1 |
| IGFBP7 | insulin-like growth factor binding protein 7 |
| IL17RB | interleukin 17 receptor B |
| IRS2 | insulin receptor substrate 2 |
| ITM2A | integral membrane protein 2A |
| LEF1 | lymphoid enhancer-binding factor 1 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| LXN | latexin |
| MARC1 | mitochondrial amidoxime reducing component 1 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 |
| NID2 | nidogen 2 (osteonidogen) |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) |
| PDIA3 | protein disulfide isomerase family A, member 3 |
| PDZD2 | PDZ domain containing 2 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma |
| PODXL | podocalyxin-like |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 |
| RHOBTB3 | Rho-related BTB domain containing 3 |
| RXRA | retinoid X receptor, alpha |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SORD | sorbitol dehydrogenase |
| SPON1 | spondin 1, extracellular matrix protein |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) |
| TFF1 | trefoil factor 1 |
| THY1 | Thy-1 cell surface antigen |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| WWOX | WW domain containing oxidoreductase |
