BRD-K98079119_2,4-difluoro-N-{4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl}benzamide_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

36 genes differentially expressed following the BRD-K98079119_2,4-difluoro-N-{4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl}benzamide_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide
CTSC cathepsin C
CXCL12 chemokine (C-X-C motif) ligand 12
EMX2 empty spiracles homeobox 2
LPXN leupaxin
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
NME4 NME/NM23 nucleoside diphosphate kinase 4
QPCT glutaminyl-peptide cyclotransferase
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
S100A7 S100 calcium binding protein A7
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SOX9 SRY (sex determining region Y)-box 9
SRPX sushi-repeat containing protein, X-linked
TGM2 transglutaminase 2
ZBTB18 zinc finger and BTB domain containing 18

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ALB albumin
ARMCX2 armadillo repeat containing, X-linked 2
CLC Charcot-Leyden crystal galectin
CPE carboxypeptidase E
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
EPAS1 endothelial PAS domain protein 1
GSTM3 glutathione S-transferase mu 3 (brain)
KRT20 keratin 20, type I
METTL7A methyltransferase like 7A
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PLVAP plasmalemma vesicle associated protein
RBP4 retinol binding protein 4, plasma
SCUBE2 signal peptide, CUB domain, EGF-like 2
SPINK1 serine peptidase inhibitor, Kazal type 1
THBS2 thrombospondin 2
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
VTCN1 V-set domain containing T cell activation inhibitor 1
ZNF91 zinc finger protein 91
Funding