BRD-K98203492_GSK-J4_HA1E_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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58 genes differentially expressed following the BRD-K98203492_GSK-J4_HA1E_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AQP3 aquaporin 3 (Gill blood group)
ASS1 argininosuccinate synthase 1
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
CALM3 calmodulin 3 (phosphorylase kinase, delta)
CD44 CD44 molecule (Indian blood group)
CHN1 chimerin 1
DST dystonin
DUSP6 dual specificity phosphatase 6
EFHD1 EF-hand domain family, member D1
ELANE elastase, neutrophil expressed
EMP1 epithelial membrane protein 1
FGFR2 fibroblast growth factor receptor 2
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon
GOT1 glutamic-oxaloacetic transaminase 1, soluble
HEPH hephaestin
HSPA2 heat shock 70kDa protein 2
IFI27 interferon, alpha-inducible protein 27
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IL1R1 interleukin 1 receptor, type I
IQGAP1 IQ motif containing GTPase activating protein 1
IRF6 interferon regulatory factor 6
KRT15 keratin 15, type I
MARCKS myristoylated alanine-rich protein kinase C substrate
MBNL2 muscleblind-like splicing regulator 2
MTSS1 metastasis suppressor 1
POSTN periostin, osteoblast specific factor
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A2 secretoglobin, family 2A, member 2
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SPRED2 sprouty-related, EVH1 domain containing 2
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
TLR4 toll-like receptor 4
TRIM2 tripartite motif containing 2
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
CCDC92 coiled-coil domain containing 92
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CPVL carboxypeptidase, vitellogenic-like
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL12 chemokine (C-X-C motif) ligand 12
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FABP5 fatty acid binding protein 5 (psoriasis-associated)
KDM5D lysine (K)-specific demethylase 5D
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MOK MOK protein kinase
NNMT nicotinamide N-methyltransferase
ODC1 ornithine decarboxylase 1
PRDX4 peroxiredoxin 4
RPS4Y1 ribosomal protein S4, Y-linked 1
SRGN serglycin
TCTN1 tectonic family member 1
TFPI2 tissue factor pathway inhibitor 2
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TUSC3 tumor suppressor candidate 3
USP9Y ubiquitin specific peptidase 9, Y-linked