BRD-K98714523_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

36 genes differentially expressed following the BRD-K98714523_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
ANO1 anoctamin 1, calcium activated chloride channel
DDIT4 DNA-damage-inducible transcript 4
FBLN1 fibulin 1
IFI44L interferon-induced protein 44-like
LAMA4 laminin, alpha 4
MLPH melanophilin
MTA1 metastasis associated 1
NR2F1 nuclear receptor subfamily 2, group F, member 1
PDAP1 PDGFA associated protein 1
PPIC peptidylprolyl isomerase C (cyclophilin C)
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
TRIB2 tribbles pseudokinase 2

decreased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ACAT2 acetyl-CoA acetyltransferase 2
ALCAM activated leukocyte cell adhesion molecule
C5ORF30 chromosome 5 open reading frame 30
CKS2 CDC28 protein kinase regulatory subunit 2
CNIH1 cornichon family AMPA receptor auxiliary protein 1
CXCL12 chemokine (C-X-C motif) ligand 12
EVI2A ecotropic viral integration site 2A
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GCH1 GTP cyclohydrolase 1
HHEX hematopoietically expressed homeobox
IDI1 isopentenyl-diphosphate delta isomerase 1
MSH6 mutS homolog 6
NPY1R neuropeptide Y receptor Y1
PDE10A phosphodiesterase 10A
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
SC5D sterol-C5-desaturase
SGK1 serum/glucocorticoid regulated kinase 1
TSPYL5 TSPY-like 5
TXNDC9 thioredoxin domain containing 9