| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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306 genes differentially expressed following the BRD-K99252563_QL-XII-47_HME1_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| AGFG1 | ArfGAP with FG repeats 1 |
| AHNAK | AHNAK nucleoprotein |
| AHNAK2 | AHNAK nucleoprotein 2 |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ANXA1 | annexin A1 |
| ARAP2 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 |
| ATF3 | activating transcription factor 3 |
| ATF4 | activating transcription factor 4 |
| ATG101 | autophagy related 101 |
| BIRC2 | baculoviral IAP repeat containing 2 |
| BMP2 | bone morphogenetic protein 2 |
| BRD2 | bromodomain containing 2 |
| BTG3 | BTG family, member 3 |
| CCND1 | cyclin D1 |
| CD24 | CD24 molecule |
| CD36 | CD36 molecule (thrombospondin receptor) |
| CDK6 | cyclin-dependent kinase 6 |
| CGRRF1 | cell growth regulator with ring finger domain 1 |
| CLDN3 | claudin 3 |
| CLGN | calmegin |
| COBL | cordon-bleu WH2 repeat protein |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial |
| CRABP1 | cellular retinoic acid binding protein 1 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 |
| CSNK1A1 | casein kinase 1, alpha 1 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
| DLX2 | distal-less homeobox 2 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DSP | desmoplakin |
| DUSP1 | dual specificity phosphatase 1 |
| EGFR | epidermal growth factor receptor |
| EIF2S1 | eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa |
| EPCAM | epithelial cell adhesion molecule |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 |
| FBXO11 | F-box protein 11 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) |
| FGF13 | fibroblast growth factor 13 |
| FGF2 | fibroblast growth factor 2 (basic) |
| FGL1 | fibrinogen-like 1 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| FNTA | farnesyltransferase, CAAX box, alpha |
| FOSL1 | FOS-like antigen 1 |
| FOXD1 | forkhead box D1 |
| FTH1 | ferritin, heavy polypeptide 1 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GALE | UDP-galactose-4-epimerase |
| GLS | glutaminase |
| GMFB | glia maturation factor, beta |
| GOLGA8A | golgin A8 family, member A |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A |
| HBEGF | heparin-binding EGF-like growth factor |
| HMOX1 | heme oxygenase 1 |
| IER2 | immediate early response 2 |
| IER3 | immediate early response 3 |
| IER5 | immediate early response 5 |
| IFRD1 | interferon-related developmental regulator 1 |
| IRS2 | insulin receptor substrate 2 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| JUN | jun proto-oncogene |
| KCMF1 | potassium channel modulatory factor 1 |
| KCTD5 | potassium channel tetramerization domain containing 5 |
| KDM5B | lysine (K)-specific demethylase 5B |
| KDM5D | lysine (K)-specific demethylase 5D |
| KLF10 | Kruppel-like factor 10 |
| KLF4 | Kruppel-like factor 4 (gut) |
| KLF6 | Kruppel-like factor 6 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) |
| KRAS | Kirsten rat sarcoma viral oncogene homolog |
| KRT17 | keratin 17, type I |
| KYNU | kynureninase |
| LGALS3 | lectin, galactoside-binding, soluble, 3 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 |
| LIF | leukemia inhibitory factor |
| LIMCH1 | LIM and calponin homology domains 1 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MARCH7 | membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase |
| MED13 | mediator complex subunit 13 |
| MIR22HG | MIR22 host gene |
| NBPF10 | neuroblastoma breakpoint family, member 10 |
| NCF2 | neutrophil cytosolic factor 2 |
| NOL7 | nucleolar protein 7, 27kDa |
| NOTCH2NL | notch 2 N-terminal like |
| NRG1 | neuregulin 1 |
| PAEP | progestagen-associated endometrial protein |
| PDZK1IP1 | PDZK1 interacting protein 1 |
| PEG3 | paternally expressed 3 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PSMD9 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 |
| PTBP2 | polypyrimidine tract binding protein 2 |
| QKI | QKI, KH domain containing, RNA binding |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) |
| RBM34 | RNA binding motif protein 34 |
| RBM47 | RNA binding motif protein 47 |
| REG1A | regenerating islet-derived 1 alpha |
| RGCC | regulator of cell cycle |
| RIOK3 | RIO kinase 3 |
| RND3 | Rho family GTPase 3 |
| RNMT | RNA (guanine-7-) methyltransferase |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SATB2 | SATB homeobox 2 |
| SCG5 | secretogranin V |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SEC61G | Sec61 gamma subunit |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SERTAD2 | SERTA domain containing 2 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) |
| SIRT1 | sirtuin 1 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC35F2 | solute carrier family 35, member F2 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SNX11 | sorting nexin 11 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 |
| SQSTM1 | sequestosome 1 |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| STC2 | stanniocalcin 2 |
| STX1A | syntaxin 1A (brain) |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit |
| TBL2 | transducin (beta)-like 2 |
| TFE3 | transcription factor binding to IGHM enhancer 3 |
| TGIF1 | TGFB-induced factor homeobox 1 |
| TMPRSS3 | transmembrane protease, serine 3 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
| TNPO1 | transportin 1 |
| TRIB1 | tribbles pseudokinase 1 |
| TUBB2A | tubulin, beta 2A class IIa |
| TUBB2B | tubulin, beta 2B class IIb |
| TXNRD1 | thioredoxin reductase 1 |
| TYMP | thymidine phosphorylase |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 |
| UGDH | UDP-glucose 6-dehydrogenase |
| UPP1 | uridine phosphorylase 1 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa |
| VEGFA | vascular endothelial growth factor A |
| WDR43 | WD repeat domain 43 |
| XBP1 | X-box binding protein 1 |
| YTHDC1 | YTH domain containing 1 |
| ZCCHC6 | zinc finger, CCHC domain containing 6 |
| ZNF451 | zinc finger protein 451 |
| Symbol | Name |
|---|---|
| ACTA2 | actin, alpha 2, smooth muscle, aorta |
| ADAM10 | ADAM metallopeptidase domain 10 |
| ADD3 | adducin 3 (gamma) |
| ADGRF5 | adhesion G protein-coupled receptor F5 |
| ADI1 | acireductone dioxygenase 1 |
| AEBP1 | AE binding protein 1 |
| AHCY | adenosylhomocysteinase |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 |
| ALDOC | aldolase C, fructose-bisphosphate |
| AQP1 | aquaporin 1 (Colton blood group) |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 |
| B3GNT1 | |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 |
| BGN | biglycan |
| C7 | complement component 7 |
| CALD1 | caldesmon 1 |
| CALM3 | calmodulin 3 (phosphorylase kinase, delta) |
| CALR | calreticulin |
| CANT1 | calcium activated nucleotidase 1 |
| CAV1 | caveolin 1, caveolae protein, 22kDa |
| CCNA2 | cyclin A2 |
| CCNG1 | cyclin G1 |
| CD200 | CD200 molecule |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
| CETN2 | centrin, EF-hand protein, 2 |
| CFH | complement factor H |
| CFI | complement factor I |
| COL1A1 | collagen, type I, alpha 1 |
| COL1A2 | collagen, type I, alpha 2 |
| COL3A1 | collagen, type III, alpha 1 |
| COL4A1 | collagen, type IV, alpha 1 |
| COL6A3 | collagen, type VI, alpha 3 |
| CRELD2 | cysteine-rich with EGF-like domains 2 |
| CRTAP | cartilage associated protein |
| CST3 | cystatin C |
| CSTA | cystatin A (stefin A) |
| CXCL12 | chemokine (C-X-C motif) ligand 12 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 |
| DAG1 | dystroglycan 1 (dystrophin-associated glycoprotein 1) |
| DCN | decorin |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| DHCR7 | 7-dehydrocholesterol reductase |
| DPYSL2 | dihydropyrimidinase-like 2 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| FASN | fatty acid synthase |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 |
| FHL1 | four and a half LIM domains 1 |
| FUCA1 | fucosidase, alpha-L- 1, tissue |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 |
| GLUD1 | glutamate dehydrogenase 1 |
| GLUD2 | glutamate dehydrogenase 2 |
| GPD1L | glycerol-3-phosphate dehydrogenase 1-like |
| GYPC | glycophorin C (Gerbich blood group) |
| HADH | hydroxyacyl-CoA dehydrogenase |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HNMT | histamine N-methyltransferase |
| HOXB2 | homeobox B2 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 |
| HSPA8 | heat shock 70kDa protein 8 |
| HSPB1 | heat shock 27kDa protein 1 |
| HTRA1 | HtrA serine peptidase 1 |
| IFI16 | interferon, gamma-inducible protein 16 |
| IGFBP4 | insulin-like growth factor binding protein 4 |
| IGFBP7 | insulin-like growth factor binding protein 7 |
| IGL | immunoglobulin lambda locus |
| INSIG1 | insulin induced gene 1 |
| ISYNA1 | inositol-3-phosphate synthase 1 |
| KAZN | kazrin, periplakin interacting protein |
| KIAA0101 | KIAA0101 |
| KIF20A | kinesin family member 20A |
| LAMB1 | laminin, beta 1 |
| LAPTM4B | lysosomal protein transmembrane 4 beta |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| LIG1 | ligase I, DNA, ATP-dependent |
| LIPA | lipase A, lysosomal acid, cholesterol esterase |
| LOXL1 | lysyl oxidase-like 1 |
| LUM | lumican |
| LY6E | lymphocyte antigen 6 complex, locus E |
| MAGED1 | melanoma antigen family D1 |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 |
| MANSC1 | MANSC domain containing 1 |
| MCAM | melanoma cell adhesion molecule |
| METTL7A | methyltransferase like 7A |
| MGAT4A | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A |
| MGP | matrix Gla protein |
| MPZL2 | myelin protein zero-like 2 |
| MSMO1 | methylsterol monooxygenase 1 |
| MTMR4 | myotubularin related protein 4 |
| MYCBP | MYC binding protein |
| NAP1L1 | nucleosome assembly protein 1-like 1 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 |
| NDN | necdin, melanoma antigen (MAGE) family member |
| NNMT | nicotinamide N-methyltransferase |
| NT5DC2 | 5'-nucleotidase domain containing 2 |
| PAM | peptidylglycine alpha-amidating monooxygenase |
| PARP1 | poly (ADP-ribose) polymerase 1 |
| PBX1 | pre-B-cell leukemia homeobox 1 |
| PCBD1 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha |
| PDCD6 | programmed cell death 6 |
| PDIA4 | protein disulfide isomerase family A, member 4 |
| PHGDH | phosphoglycerate dehydrogenase |
| PLTP | phospholipid transfer protein |
| POSTN | periostin, osteoblast specific factor |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRSS23 | protease, serine, 23 |
| PSCA | prostate stem cell antigen |
| PSIP1 | PC4 and SFRS1 interacting protein 1 |
| PSME1 | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) |
| PTGIS | prostaglandin I2 (prostacyclin) synthase |
| RAC2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
| RBPMS | RNA binding protein with multiple splicing |
| RCN2 | reticulocalbin 2, EF-hand calcium binding domain |
| RGS1 | regulator of G-protein signaling 1 |
| RGS2 | regulator of G-protein signaling 2 |
| RGS5 | regulator of G-protein signaling 5 |
| RPA1 | replication protein A1, 70kDa |
| RPA3 | replication protein A3, 14kDa |
| RPN2 | ribophorin II |
| RRM2 | ribonucleotide reductase M2 |
| RTN1 | reticulon 1 |
| SCARB2 | scavenger receptor class B, member 2 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SEPP1 | selenoprotein P, plasma, 1 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase |
| SMC2 | structural maintenance of chromosomes 2 |
| SNX10 | sorting nexin 10 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) |
| SQLE | squalene epoxidase |
| SRGN | serglycin |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STMN1 | stathmin 1 |
| SULF1 | sulfatase 1 |
| TBC1D16 | TBC1 domain family, member 16 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| THBS1 | thrombospondin 1 |
| THBS2 | thrombospondin 2 |
| TIMELESS | timeless circadian clock |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TMEM2 | transmembrane protein 2 |
| TMEM97 | transmembrane protein 97 |
| TMSB15A | thymosin beta 15a |
| TNC | tenascin C |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TSC22D3 | TSC22 domain family, member 3 |
| TSPYL4 | TSPY-like 4 |
| TUBB | tubulin, beta class I |
| VCAM1 | vascular cell adhesion molecule 1 |
