BRD-K99502566_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

48 genes differentially expressed following the BRD-K99502566_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADM adrenomedullin
AMIGO2 adhesion molecule with Ig-like domain 2
C9ORF3 chromosome 9 open reading frame 3
CDC42 cell division cycle 42
CEMIP cell migration inducing protein, hyaluronan binding
CHIC2 cysteine-rich hydrophobic domain 2
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CXCL8 chemokine (C-X-C motif) ligand 8
DDIT4 DNA-damage-inducible transcript 4
DDR1 discoidin domain receptor tyrosine kinase 1
DSP desmoplakin
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
GSTM3 glutathione S-transferase mu 3 (brain)
HOXC6 homeobox C6
IER3 immediate early response 3
IFI6 interferon, alpha-inducible protein 6
IL1B interleukin 1, beta
ISG15 ISG15 ubiquitin-like modifier
LTBP3 latent transforming growth factor beta binding protein 3
MAP7 microtubule-associated protein 7
MMP1 matrix metallopeptidase 1
MT1M metallothionein 1M
PLAC8 placenta-specific 8
RAB25 RAB25, member RAS oncogene family
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RHOB ras homolog family member B
S100A4 S100 calcium binding protein A4
S100B S100 calcium binding protein B
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SMAD3 SMAD family member 3
TCF7 transcription factor 7 (T-cell specific, HMG-box)
TPD52L1 tumor protein D52-like 1
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon

decreased expression

Symbol Name
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ASS1 argininosuccinate synthase 1
CCND2 cyclin D2
CFB complement factor B
CLU clusterin
COL4A5 collagen, type IV, alpha 5
CXCL9 chemokine (C-X-C motif) ligand 9
LTF lactotransferrin
MUC16 mucin 16, cell surface associated
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SFRP1 secreted frizzled-related protein 1
SLPI secretory leukocyte peptidase inhibitor