| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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108 genes differentially expressed following the BRD-K99633092_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ADM | adrenomedullin |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 |
| AQP3 | aquaporin 3 (Gill blood group) |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide |
| BCL3 | B-cell CLL/lymphoma 3 |
| C1QA | complement component 1, q subcomponent, A chain |
| C1QB | complement component 1, q subcomponent, B chain |
| C1S | complement component 1, s subcomponent |
| CA12 | carbonic anhydrase XII |
| CA2 | carbonic anhydrase II |
| CD163 | CD163 molecule |
| CD24 | CD24 molecule |
| CD44 | CD44 molecule (Indian blood group) |
| CGRRF1 | cell growth regulator with ring finger domain 1 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP5 | dual specificity phosphatase 5 |
| EFNA1 | ephrin-A1 |
| FOSL1 | FOS-like antigen 1 |
| FZD6 | frizzled class receptor 6 |
| GCLC | glutamate-cysteine ligase, catalytic subunit |
| H2BFS | H2B histone family, member S (pseudogene) |
| HIST1H1C | histone cluster 1, H1c |
| HIST1H2BK | histone cluster 1, H2bk |
| HMOX1 | heme oxygenase 1 |
| HSPA1A | heat shock 70kDa protein 1A |
| IGHM | immunoglobulin heavy constant mu |
| KIAA0226L | KIAA0226-like |
| KLHL24 | kelch-like family member 24 |
| KRT6A | keratin 6A, type II |
| LAPTM4B | lysosomal protein transmembrane 4 beta |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
| MMP9 | matrix metallopeptidase 9 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) |
| NRCAM | neuronal cell adhesion molecule |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OSER1 | oxidative stress responsive serine-rich 1 |
| PLK2 | polo-like kinase 2 |
| PMP22 | peripheral myelin protein 22 |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| SFN | stratifin |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SOWAHC | sosondowah ankyrin repeat domain family member C |
| SPRR1A | small proline-rich protein 1A |
| SPRR2B | small proline-rich protein 2B |
| SPRR3 | small proline-rich protein 3 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) |
| TPD52 | tumor protein D52 |
| TRIB3 | tribbles pseudokinase 3 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TXNRD1 | thioredoxin reductase 1 |
| VEGFA | vascular endothelial growth factor A |
| WNT5A | wingless-type MMTV integration site family, member 5A |
| YBX3 | Y box binding protein 3 |
| Symbol | Name |
|---|---|
| ABAT | 4-aminobutyrate aminotransferase |
| ACAA1 | acetyl-CoA acyltransferase 1 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta |
| ADD3 | adducin 3 (gamma) |
| AGTR1 | angiotensin II receptor, type 1 |
| ALDOB | aldolase B, fructose-bisphosphate |
| AMBP | alpha-1-microglobulin/bikunin precursor |
| APOC3 | apolipoprotein C-III |
| C7 | complement component 7 |
| CIRBP | cold inducible RNA binding protein |
| CXCL12 | chemokine (C-X-C motif) ligand 12 |
| CYBA | cytochrome b-245, alpha polypeptide |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 |
| DCXR | dicarbonyl/L-xylulose reductase |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DPT | dermatopontin |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) |
| GLDC | glycine dehydrogenase (decarboxylating) |
| GMDS | GDP-mannose 4,6-dehydratase |
| GPX3 | glutathione peroxidase 3 |
| IL17RB | interleukin 17 receptor B |
| IL33 | interleukin 33 |
| ITM2A | integral membrane protein 2A |
| LEPR | leptin receptor |
| MARCKSL1 | MARCKS-like 1 |
| METTL7A | methyltransferase like 7A |
| PAH | phenylalanine hydroxylase |
| PDZK1 | PDZ domain containing 1 |
| PEBP1 | phosphatidylethanolamine binding protein 1 |
| POSTN | periostin, osteoblast specific factor |
| PTGIS | prostaglandin I2 (prostacyclin) synthase |
| RBP4 | retinol binding protein 4, plasma |
| RELN | reelin |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SERPIND1 | serpin peptidase inhibitor, clade D (heparin cofactor), member 1 |
| SORD | sorbitol dehydrogenase |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing |
| SRPX | sushi-repeat containing protein, X-linked |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TF | transferrin |
| TFF1 | trefoil factor 1 |
| TGFBR3 | transforming growth factor, beta receptor III |
| THBS2 | thrombospondin 2 |
| TJP2 | tight junction protein 2 |
| TLR4 | toll-like receptor 4 |
| TMPRSS3 | transmembrane protease, serine 3 |
| UBE2C | ubiquitin-conjugating enzyme E2C |
| VNN1 | vanin 1 |
