| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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163 genes differentially expressed following the BRD-K99749624_linifanib_HME1_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ADD3 | adducin 3 (gamma) |
| ANXA4 | annexin A4 |
| APOA1 | apolipoprotein A-I |
| AREG | amphiregulin |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| ASPN | asporin |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide |
| BCHE | butyrylcholinesterase |
| BCL6 | B-cell CLL/lymphoma 6 |
| C7 | complement component 7 |
| CAP2 | CAP, adenylate cyclase-associated protein, 2 (yeast) |
| CD36 | CD36 molecule (thrombospondin receptor) |
| CD99 | CD99 molecule |
| CDC42 | cell division cycle 42 |
| CFI | complement factor I |
| CTSH | cathepsin H |
| CXADR | coxsackie virus and adenovirus receptor |
| DEFB1 | defensin, beta 1 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) |
| EPCAM | epithelial cell adhesion molecule |
| FASTKD5 | FAST kinase domains 5 |
| FGFR3 | fibroblast growth factor receptor 3 |
| FGG | fibrinogen gamma chain |
| FOXG1 | forkhead box G1 |
| FXYD2 | FXYD domain containing ion transport regulator 2 |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GPX3 | glutathione peroxidase 3 |
| GSTA1 | glutathione S-transferase alpha 1 |
| HAMP | hepcidin antimicrobial peptide |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
| HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| KLF10 | Kruppel-like factor 10 |
| KRT8 | keratin 8, type II |
| LAPTM4B | lysosomal protein transmembrane 4 beta |
| LEPROT | leptin receptor overlapping transcript |
| LGALS2 | lectin, galactoside-binding, soluble, 2 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| LTA4H | leukotriene A4 hydrolase |
| LYZ | lysozyme |
| MAOB | monoamine oxidase B |
| MEIS2 | Meis homeobox 2 |
| NFIL3 | nuclear factor, interleukin 3 regulated |
| NMU | neuromedin U |
| NREP | neuronal regeneration related protein |
| OAT | ornithine aminotransferase |
| OLFM4 | olfactomedin 4 |
| PAPSS1 | 3'-phosphoadenosine 5'-phosphosulfate synthase 1 |
| PCMTD2 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 |
| PEG10 | paternally expressed 10 |
| PHACTR2 | phosphatase and actin regulator 2 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
| PLBD1 | phospholipase B domain containing 1 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PLK2 | polo-like kinase 2 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRAME | preferentially expressed antigen in melanoma |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) |
| PRNP | prion protein |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) |
| REEP1 | receptor accessory protein 1 |
| S100A10 | S100 calcium binding protein A10 |
| SCG2 | secretogranin II |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 |
| SLIT2 | slit homolog 2 (Drosophila) |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) |
| SYNGR1 | synaptogyrin 1 |
| TP53BP2 | tumor protein p53 binding protein 2 |
| TSPAN13 | tetraspanin 13 |
| TXNIP | thioredoxin interacting protein |
| UGCG | UDP-glucose ceramide glucosyltransferase |
| VCAN | versican |
| Symbol | Name |
|---|---|
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
| BASP1 | brain abundant, membrane attached signal protein 1 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| CBLB | Cbl proto-oncogene B, E3 ubiquitin protein ligase |
| CBR3 | carbonyl reductase 3 |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CCL4 | chemokine (C-C motif) ligand 4 |
| CCNF | cyclin F |
| CD69 | CD69 molecule |
| CD9 | CD9 molecule |
| CDC25B | cell division cycle 25B |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| COL5A1 | collagen, type V, alpha 1 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog |
| CST7 | cystatin F (leukocystatin) |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
| CXCL13 | chemokine (C-X-C motif) ligand 13 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DUSP4 | dual specificity phosphatase 4 |
| DUSP5 | dual specificity phosphatase 5 |
| EFHD2 | EF-hand domain family, member D2 |
| FASN | fatty acid synthase |
| FCGBP | Fc fragment of IgG binding protein |
| FHL2 | four and a half LIM domains 2 |
| FTH1 | ferritin, heavy polypeptide 1 |
| GPR137B | G protein-coupled receptor 137B |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 |
| HMGA2 | high mobility group AT-hook 2 |
| ICAM1 | intercellular adhesion molecule 1 |
| IGHM | immunoglobulin heavy constant mu |
| IL1B | interleukin 1, beta |
| INSIG1 | insulin induced gene 1 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| ITGAV | integrin, alpha V |
| JADE2 | jade family PHD finger 2 |
| KCTD5 | potassium channel tetramerization domain containing 5 |
| KRT17 | keratin 17, type I |
| KRT7 | keratin 7, type II |
| KYNU | kynureninase |
| LAMB3 | laminin, beta 3 |
| LAMC2 | laminin, gamma 2 |
| LTF | lactotransferrin |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 |
| MMP12 | matrix metallopeptidase 12 |
| MMP3 | matrix metallopeptidase 3 |
| NKX3-1 | NK3 homeobox 1 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
| NUP62 | nucleoporin 62kDa |
| PBX3 | pre-B-cell leukemia homeobox 3 |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PIP | prolactin-induced protein |
| POPDC3 | popeye domain containing 3 |
| POU2AF1 | POU class 2 associating factor 1 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma |
| PTGES | prostaglandin E synthase |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RUNX3 | runt-related transcription factor 3 |
| S100A2 | S100 calcium binding protein A2 |
| S100A7 | S100 calcium binding protein A7 |
| SCGB1D2 | secretoglobin, family 1D, member 2 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SFN | stratifin |
| SPTSSA | serine palmitoyltransferase, small subunit A |
| SQSTM1 | sequestosome 1 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein |
| SYNJ2 | synaptojanin 2 |
| TBX3 | T-box 3 |
| TFAP2B | transcription factor AP-2 beta (activating enhancer binding protein 2 beta) |
| TMEM2 | transmembrane protein 2 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TRIM16 | tripartite motif containing 16 |
| TRIM29 | tripartite motif containing 29 |
| TSC22D3 | TSC22 domain family, member 3 |
| UST | uronyl-2-sulfotransferase |
| ZMIZ1 | zinc finger, MIZ-type containing 1 |
