BRD-M73371355_R(-) Apomorphine hydrochloride hemihydrate_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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51 genes differentially expressed following the BRD-M73371355_R(-) Apomorphine hydrochloride hemihydrate_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ANXA3 annexin A3
ANXA5 annexin A5
BEX1 brain expressed, X-linked 1
BST2 bone marrow stromal cell antigen 2
CST3 cystatin C
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FAM46A family with sequence similarity 46, member A
HOXC6 homeobox C6
HSPD1 heat shock 60kDa protein 1 (chaperonin)
KDM5D lysine (K)-specific demethylase 5D
KIAA0100 KIAA0100
PHACTR2 phosphatase and actin regulator 2
PLSCR1 phospholipid scramblase 1
RPS11 ribosomal protein S11
SEPP1 selenoprotein P, plasma, 1
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TACSTD2 tumor-associated calcium signal transducer 2
TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFF1 trefoil factor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TSPAN8 tetraspanin 8
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ADAMDEC1 ADAM-like, decysin 1
AQP1 aquaporin 1 (Colton blood group)
CAV1 caveolin 1, caveolae protein, 22kDa
CD44 CD44 molecule (Indian blood group)
CYTIP cytohesin 1 interacting protein
EFNB2 ephrin-B2
EMP1 epithelial membrane protein 1
FN1 fibronectin 1
HIST1H1C histone cluster 1, H1c
HOXD1 homeobox D1
IGKV4-1 immunoglobulin kappa variable 4-1
ISOC1 isochorismatase domain containing 1
KRT15 keratin 15, type I
NVL nuclear VCP-like
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PDE4B phosphodiesterase 4B, cAMP-specific
PRKX protein kinase, X-linked
PRUNE2 prune homolog 2 (Drosophila)
RGCC regulator of cell cycle
RGS1 regulator of G-protein signaling 1
RTN1 reticulon 1
TMEM158 transmembrane protein 158 (gene/pseudogene)
VEGFA vascular endothelial growth factor A
XIST X inactive specific transcript (non-protein coding)