BRD-U04166717_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

47 genes differentially expressed following the BRD-U04166717_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADIRF adipogenesis regulatory factor
ARL4C ADP-ribosylation factor-like 4C
CD24 CD24 molecule
CFB complement factor B
CTGF connective tissue growth factor
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FBXL12 F-box and leucine-rich repeat protein 12
FHL1 four and a half LIM domains 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IGFBP5 insulin-like growth factor binding protein 5
INSIG1 insulin induced gene 1
JAG1 jagged 1
KIAA0226L KIAA0226-like
MTSS1 metastasis suppressor 1
OBSL1 obscurin-like 1
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PRSS2 protease, serine, 2 (trypsin 2)
PRSS3 protease, serine, 3
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
TBX3 T-box 3
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
VEGFC vascular endothelial growth factor C
VLDLR very low density lipoprotein receptor

decreased expression

Symbol Name
ATF5 activating transcription factor 5
BRCA1 breast cancer 1, early onset
CD58 CD58 molecule
CDC45 cell division cycle 45
CENPU centromere protein U
COG2 component of oligomeric golgi complex 2
COL3A1 collagen, type III, alpha 1
CXCL14 chemokine (C-X-C motif) ligand 14
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9
GCLM glutamate-cysteine ligase, modifier subunit
GGCT gamma-glutamylcyclotransferase
GINS2 GINS complex subunit 2 (Psf2 homolog)
HOPX HOP homeobox
HSPA1A heat shock 70kDa protein 1A
HTRA1 HtrA serine peptidase 1
LYPLA1 lysophospholipase I
NQO2 NAD(P)H dehydrogenase, quinone 2
NUP85 nucleoporin 85kDa
PCNA proliferating cell nuclear antigen
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
RAD51C RAD51 paralog C
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)