| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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123 genes differentially expressed following the BRD-U07805514_saracatinib_PC3_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| AHNAK | AHNAK nucleoprotein |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit |
| AREG | amphiregulin |
| ATF3 | activating transcription factor 3 |
| BAX | BCL2-associated X protein |
| BST2 | bone marrow stromal cell antigen 2 |
| CD24 | CD24 molecule |
| CD59 | CD59 molecule, complement regulatory protein |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) |
| CTSB | cathepsin B |
| CTSZ | cathepsin Z |
| CXADR | coxsackie virus and adenovirus receptor |
| CXCL14 | chemokine (C-X-C motif) ligand 14 |
| DCLK1 | doublecortin-like kinase 1 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 |
| DEFB1 | defensin, beta 1 |
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta |
| EMP3 | epithelial membrane protein 3 |
| EOGT | EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase |
| FN1 | fibronectin 1 |
| GDF15 | growth differentiation factor 15 |
| GLIPR1 | GLI pathogenesis-related 1 |
| H3F3B | H3 histone, family 3B (H3.3B) |
| HIRA | histone cell cycle regulator |
| HK1 | hexokinase 1 |
| HMOX1 | heme oxygenase 1 |
| IER5 | immediate early response 5 |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| JUN | jun proto-oncogene |
| KRT14 | keratin 14, type I |
| KRT23 | keratin 23, type I |
| LCN2 | lipocalin 2 |
| LMNA | lamin A/C |
| LPL | lipoprotein lipase |
| LXN | latexin |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MGLL | monoglyceride lipase |
| MMP9 | matrix metallopeptidase 9 |
| MT1H | metallothionein 1H |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NRIP1 | nuclear receptor interacting protein 1 |
| PCYOX1 | prenylcysteine oxidase 1 |
| PDGFC | platelet derived growth factor C |
| PDLIM4 | PDZ and LIM domain 4 |
| PERP | PERP, TP53 apoptosis effector |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| PRNP | prion protein |
| PRR7 | proline rich 7 (synaptic) |
| SFN | stratifin |
| SIK1 | salt-inducible kinase 1 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 |
| SRGN | serglycin |
| STOM | stomatin |
| TACSTD2 | tumor-associated calcium signal transducer 2 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TNC | tenascin C |
| TNPO1 | transportin 1 |
| TOB1 | transducer of ERBB2, 1 |
| XIST | X inactive specific transcript (non-protein coding) |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZNF185 | zinc finger protein 185 (LIM domain) |
| Symbol | Name |
|---|---|
| ACD | adrenocortical dysplasia homolog (mouse) |
| AGR2 | anterior gradient 2 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| AURKB | aurora kinase B |
| CALM3 | calmodulin 3 (phosphorylase kinase, delta) |
| CCL4 | chemokine (C-C motif) ligand 4 |
| COL5A2 | collagen, type V, alpha 2 |
| CP | ceruloplasmin (ferroxidase) |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| EMG1 | EMG1 N1-specific pseudouridine methyltransferase |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi |
| GALE | UDP-galactose-4-epimerase |
| GATA6 | GATA binding protein 6 |
| GIMAP5 | GTPase, IMAP family member 5 |
| GRK5 | G protein-coupled receptor kinase 5 |
| GSTA1 | glutathione S-transferase alpha 1 |
| GYPC | glycophorin C (Gerbich blood group) |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) |
| GZMH | granzyme H (cathepsin G-like 2, protein h-CCPX) |
| HDAC6 | histone deacetylase 6 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| KRT18 | keratin 18, type I |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog |
| MB | myoglobin |
| MEA1 | male-enhanced antigen 1 |
| MRPL57 | mitochondrial ribosomal protein L57 |
| MYRF | myelin regulatory factor |
| NDUFAF3 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 3 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 |
| NIPSNAP1 | nipsnap homolog 1 (C. elegans) |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) |
| NRN1 | neuritin 1 |
| ORMDL2 | ORMDL sphingolipid biosynthesis regulator 2 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PEG3 | paternally expressed 3 |
| PIGP | phosphatidylinositol glycan anchor biosynthesis, class P |
| PLN | phospholamban |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B |
| ROGDI | rogdi homolog (Drosophila) |
| RPA3 | replication protein A3, 14kDa |
| RPS11 | ribosomal protein S11 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 |
| TAF10 | TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa |
| TCEAL4 | transcription elongation factor A (SII)-like 4 |
| TCTA | T-cell leukemia translocation altered |
| TES | testin LIM domain protein |
| THTPA | thiamine triphosphatase |
| TPSAB1 | tryptase alpha/beta 1 |
| TSPAN8 | tetraspanin 8 |
| UXT | ubiquitously-expressed, prefoldin-like chaperone |
| WBP5 | WW domain binding protein 5 |
