Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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128 genes differentially expressed following the BRD-U29336476_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
A2M | alpha-2-macroglobulin |
ANKRD10 | ankyrin repeat domain 10 |
AQP3 | aquaporin 3 (Gill blood group) |
ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 |
BRD2 | bromodomain containing 2 |
BSG | basigin (Ok blood group) |
C1QA | complement component 1, q subcomponent, A chain |
CCL5 | chemokine (C-C motif) ligand 5 |
CD14 | CD14 molecule |
CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
CD99 | CD99 molecule |
CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
CLEC7A | C-type lectin domain family 7, member A |
COL3A1 | collagen, type III, alpha 1 |
CREG1 | cellular repressor of E1A-stimulated genes 1 |
CTH | cystathionine gamma-lyase |
CXCL10 | chemokine (C-X-C motif) ligand 10 |
DMD | dystrophin |
DSP | desmoplakin |
EGR2 | early growth response 2 |
EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
FLNA | filamin A, alpha |
GADD45B | growth arrest and DNA-damage-inducible, beta |
GAS1 | growth arrest-specific 1 |
GJA1 | gap junction protein, alpha 1, 43kDa |
GSDMB | gasdermin B |
H2BFS | H2B histone family, member S (pseudogene) |
HIST1H1C | histone cluster 1, H1c |
HIST1H2AC | histone cluster 1, H2ac |
HIST1H2BD | histone cluster 1, H2bd |
HIST1H2BE | histone cluster 1, H2be |
HIST1H2BF | histone cluster 1, H2bf |
HIST1H2BK | histone cluster 1, H2bk |
HIST1H3H | histone cluster 1, H3h |
HOPX | HOP homeobox |
IER5 | immediate early response 5 |
IFRD1 | interferon-related developmental regulator 1 |
IGHM | immunoglobulin heavy constant mu |
MARCKSL1 | MARCKS-like 1 |
MMP12 | matrix metallopeptidase 12 |
MUC5B | mucin 5B, oligomeric mucus/gel-forming |
NEB | nebulin |
NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
NOTCH1 | notch 1 |
NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
NUSAP1 | nucleolar and spindle associated protein 1 |
PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
PEG10 | paternally expressed 10 |
PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
PLS3 | plastin 3 |
PTTG1 | pituitary tumor-transforming 1 |
RGS2 | regulator of G-protein signaling 2 |
SCARB2 | scavenger receptor class B, member 2 |
SEPT6 | septin 6 |
SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
SIK1 | salt-inducible kinase 1 |
SLC25A4 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 |
STAB1 | stabilin 1 |
TDO2 | tryptophan 2,3-dioxygenase |
TMEM158 | transmembrane protein 158 (gene/pseudogene) |
TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 |
TNNT1 | troponin T type 1 (skeletal, slow) |
TTC3 | tetratricopeptide repeat domain 3 |
TTN | titin |
TXNIP | thioredoxin interacting protein |
VNN1 | vanin 1 |
VSIG4 | V-set and immunoglobulin domain containing 4 |
Symbol | Name |
---|---|
ADCY1 | adenylate cyclase 1 (brain) |
ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide |
ADIRF | adipogenesis regulatory factor |
AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
AKR1C3 | aldo-keto reductase family 1, member C3 |
ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 |
ANXA1 | annexin A1 |
ARHGAP29 | Rho GTPase activating protein 29 |
AXL | AXL receptor tyrosine kinase |
BEX1 | brain expressed, X-linked 1 |
BHLHE41 | basic helix-loop-helix family, member e41 |
CAV2 | caveolin 2 |
CCND1 | cyclin D1 |
CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
CFD | complement factor D (adipsin) |
CTBP2 | C-terminal binding protein 2 |
DACH1 | dachshund family transcription factor 1 |
DCLK1 | doublecortin-like kinase 1 |
DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
DKK3 | dickkopf WNT signaling pathway inhibitor 3 |
EIF5A | eukaryotic translation initiation factor 5A |
EMG1 | EMG1 N1-specific pseudouridine methyltransferase |
EREG | epiregulin |
FXYD2 | FXYD domain containing ion transport regulator 2 |
GNG11 | guanine nucleotide binding protein (G protein), gamma 11 |
HMGA2 | high mobility group AT-hook 2 |
HOMER3 | homer scaffolding protein 3 |
HOXB7 | homeobox B7 |
ICAM2 | intercellular adhesion molecule 2 |
IGF1R | insulin-like growth factor 1 receptor |
IRS1 | insulin receptor substrate 1 |
JADE2 | jade family PHD finger 2 |
KCNS3 | potassium voltage-gated channel, modifier subfamily S, member 3 |
LPAR1 | lysophosphatidic acid receptor 1 |
LY6E | lymphocyte antigen 6 complex, locus E |
MOK | MOK protein kinase |
MRPL12 | mitochondrial ribosomal protein L12 |
MSLN | mesothelin |
NME4 | NME/NM23 nucleoside diphosphate kinase 4 |
NR2F6 | nuclear receptor subfamily 2, group F, member 6 |
OGDHL | oxoglutarate dehydrogenase-like |
PKP4 | plakophilin 4 |
PLA1A | phospholipase A1 member A |
PLAC8 | placenta-specific 8 |
POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit |
PPARG | peroxisome proliferator-activated receptor gamma |
PRSS23 | protease, serine, 23 |
RGS5 | regulator of G-protein signaling 5 |
SLC19A1 | solute carrier family 19 (folate transporter), member 1 |
SLC39A4 | solute carrier family 39 (zinc transporter), member 4 |
SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 |
SPRY2 | sprouty homolog 2 (Drosophila) |
SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
TFAP2B | transcription factor AP-2 beta (activating enhancer binding protein 2 beta) |
TFPI2 | tissue factor pathway inhibitor 2 |
TSPYL5 | TSPY-like 5 |
VCAN | versican |