| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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189 genes differentially expressed following the BRD-U43867373_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| AQP8 | aquaporin 8 |
| ARMCX1 | armadillo repeat containing, X-linked 1 |
| BCL2A1 | BCL2-related protein A1 |
| BEX4 | brain expressed, X-linked 4 |
| C1ORF115 | chromosome 1 open reading frame 115 |
| CA4 | carbonic anhydrase IV |
| CCL5 | chemokine (C-C motif) ligand 5 |
| CD177 | CD177 molecule |
| CD24 | CD24 molecule |
| CD36 | CD36 molecule (thrombospondin receptor) |
| CD52 | CD52 molecule |
| CDS1 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 |
| CELF2 | CUGBP, Elav-like family member 2 |
| CENPU | centromere protein U |
| CKB | creatine kinase, brain |
| CLC | Charcot-Leyden crystal galectin |
| CLDN3 | claudin 3 |
| CLIC5 | chloride intracellular channel 5 |
| CPE | carboxypeptidase E |
| CRABP1 | cellular retinoic acid binding protein 1 |
| CRABP2 | cellular retinoic acid binding protein 2 |
| CTSV | cathepsin V |
| CXCL10 | chemokine (C-X-C motif) ligand 10 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DUSP14 | dual specificity phosphatase 14 |
| EPCAM | epithelial cell adhesion molecule |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
| FBXO11 | F-box protein 11 |
| FGFR2 | fibroblast growth factor receptor 2 |
| FZD5 | frizzled class receptor 5 |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GLUL | glutamate-ammonia ligase |
| GPNMB | glycoprotein (transmembrane) nmb |
| GREB1 | growth regulation by estrogen in breast cancer 1 |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 |
| HIST1H1C | histone cluster 1, H1c |
| HIST1H2BD | histone cluster 1, H2bd |
| HIST1H4C | histone cluster 1, H4c |
| HLA-G | major histocompatibility complex, class I, G |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HOXA5 | homeobox A5 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
| IDO1 | indoleamine 2,3-dioxygenase 1 |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFI44 | interferon-induced protein 44 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| IFRD1 | interferon-related developmental regulator 1 |
| IGF1R | insulin-like growth factor 1 receptor |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| INSM1 | insulinoma-associated 1 |
| ISYNA1 | inositol-3-phosphate synthase 1 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 |
| KLF10 | Kruppel-like factor 10 |
| KLF6 | Kruppel-like factor 6 |
| MEIS2 | Meis homeobox 2 |
| MS4A12 | membrane-spanning 4-domains, subfamily A, member 12 |
| NCK1 | NCK adaptor protein 1 |
| NFIL3 | nuclear factor, interleukin 3 regulated |
| NRIP1 | nuclear receptor interacting protein 1 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
| PTN | pleiotrophin |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) |
| RGCC | regulator of cell cycle |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) |
| RSAD2 | radical S-adenosyl methionine domain containing 2 |
| S100A14 | S100 calcium binding protein A14 |
| SCG2 | secretogranin II |
| SCGB1D2 | secretoglobin, family 1D, member 2 |
| SCGB2A1 | secretoglobin, family 2A, member 1 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SERINC5 | serine incorporator 5 |
| SESN1 | sestrin 1 |
| SOCS1 | suppressor of cytokine signaling 1 |
| SPARCL1 | SPARC-like 1 (hevin) |
| ST6GALNAC5 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 |
| STXBP6 | syntaxin binding protein 6 (amisyn) |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TMEM30B | transmembrane protein 30B |
| TP53BP2 | tumor protein p53 binding protein 2 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TTC39A | tetratricopeptide repeat domain 39A |
| TXNIP | thioredoxin interacting protein |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 |
| XIST | X inactive specific transcript (non-protein coding) |
| Symbol | Name |
|---|---|
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 |
| ACTN1 | actinin, alpha 1 |
| ADGRG6 | adhesion G protein-coupled receptor G6 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| AK1 | adenylate kinase 1 |
| ANKRD10 | ankyrin repeat domain 10 |
| AQP3 | aquaporin 3 (Gill blood group) |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A |
| BIN1 | bridging integrator 1 |
| BRCA1 | breast cancer 1, early onset |
| C1RL | complement component 1, r subcomponent-like |
| C1S | complement component 1, s subcomponent |
| CAPRIN2 | caprin family member 2 |
| CCND1 | cyclin D1 |
| CCNF | cyclin F |
| CD302 | CD302 molecule |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog |
| DCN | decorin |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DIXDC1 | DIX domain containing 1 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DUSP5 | dual specificity phosphatase 5 |
| DUSP6 | dual specificity phosphatase 6 |
| EPN2 | epsin 2 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 |
| FGB | fibrinogen beta chain |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 |
| FOSL1 | FOS-like antigen 1 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) |
| GLDC | glycine dehydrogenase (decarboxylating) |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| GSTM3 | glutathione S-transferase mu 3 (brain) |
| HBB | hemoglobin, beta |
| HOPX | HOP homeobox |
| HOXC6 | homeobox C6 |
| IER3 | immediate early response 3 |
| IFRD2 | interferon-related developmental regulator 2 |
| IGFBP1 | insulin-like growth factor binding protein 1 |
| ITGA6 | integrin, alpha 6 |
| KRT7 | keratin 7, type II |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) |
| LRRC41 | leucine rich repeat containing 41 |
| LYPLA1 | lysophospholipase I |
| MACF1 | microtubule-actin crosslinking factor 1 |
| MALT1 | MALT1 paracaspase |
| MAP1B | microtubule-associated protein 1B |
| MBNL2 | muscleblind-like splicing regulator 2 |
| NNMT | nicotinamide N-methyltransferase |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| NUP62 | nucleoporin 62kDa |
| NUP85 | nucleoporin 85kDa |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit |
| PCBP4 | poly(rC) binding protein 4 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PREB | prolactin regulatory element binding |
| PRKCA | protein kinase C, alpha |
| PROS1 | protein S (alpha) |
| RECQL | RecQ helicase-like |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 |
| S100A2 | S100 calcium binding protein A2 |
| S100P | S100 calcium binding protein P |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SIK1 | salt-inducible kinase 1 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC38A1 | solute carrier family 38, member 1 |
| SLC39A4 | solute carrier family 39 (zinc transporter), member 4 |
| SPATA20 | spermatogenesis associated 20 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| SRPX2 | sushi-repeat containing protein, X-linked 2 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TFPI2 | tissue factor pathway inhibitor 2 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TMEM2 | transmembrane protein 2 |
| TMEM5 | transmembrane protein 5 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| TRAPPC3 | trafficking protein particle complex 3 |
| TUBA4A | tubulin, alpha 4a |
| UBE3C | ubiquitin protein ligase E3C |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 |
| WSB2 | WD repeat and SOCS box containing 2 |
