| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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125 genes differentially expressed following the BRD-U43867373_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABHD3 | abhydrolase domain containing 3 |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ARMCX3 | armadillo repeat containing, X-linked 3 |
| ASRGL1 | asparaginase like 1 |
| C10ORF10 | chromosome 10 open reading frame 10 |
| CAPG | capping protein (actin filament), gelsolin-like |
| CCNG2 | cyclin G2 |
| CENPE | centromere protein E, 312kDa |
| CFD | complement factor D (adipsin) |
| CSTA | cystatin A (stefin A) |
| DDIT4 | DNA-damage-inducible transcript 4 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 |
| FOXO3 | forkhead box O3 |
| FTH1 | ferritin, heavy polypeptide 1 |
| GLRX | glutaredoxin (thioltransferase) |
| GPNMB | glycoprotein (transmembrane) nmb |
| HBP1 | HMG-box transcription factor 1 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HIST1H1C | histone cluster 1, H1c |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| IFI27 | interferon, alpha-inducible protein 27 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| INSIG1 | insulin induced gene 1 |
| MAOA | monoamine oxidase A |
| METTL7A | methyltransferase like 7A |
| MFAP5 | microfibrillar associated protein 5 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NPC2 | Niemann-Pick disease, type C2 |
| NRIP1 | nuclear receptor interacting protein 1 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| RAP1GAP | RAP1 GTPase activating protein |
| RBM47 | RNA binding motif protein 47 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) |
| SELENBP1 | selenium binding protein 1 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SESN1 | sestrin 1 |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SQSTM1 | sequestosome 1 |
| SULT1A1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 |
| SULT1A2 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TRIM2 | tripartite motif containing 2 |
| TSC22D3 | TSC22 domain family, member 3 |
| TSPAN7 | tetraspanin 7 |
| UBE2B | ubiquitin-conjugating enzyme E2B |
| VAT1 | vesicle amine transport 1 |
| WFDC2 | WAP four-disulfide core domain 2 |
| Symbol | Name |
|---|---|
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| ANXA1 | annexin A1 |
| BAG2 | BCL2-associated athanogene 2 |
| BOP1 | block of proliferation 1 |
| C10ORF2 | chromosome 10 open reading frame 2 |
| CDC25A | cell division cycle 25A |
| COTL1 | coactosin-like F-actin binding protein 1 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 |
| DPH2 | DPH2 homolog (S. cerevisiae) |
| DUSP4 | dual specificity phosphatase 4 |
| DUSP6 | dual specificity phosphatase 6 |
| DUSP7 | dual specificity phosphatase 7 |
| EGR2 | early growth response 2 |
| EGR3 | early growth response 3 |
| EPHA2 | EPH receptor A2 |
| EREG | epiregulin |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FJX1 | four jointed box 1 (Drosophila) |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| FOSL1 | FOS-like antigen 1 |
| G0S2 | G0/G1 switch 2 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| HBEGF | heparin-binding EGF-like growth factor |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
| IER3 | immediate early response 3 |
| INPP1 | inositol polyphosphate-1-phosphatase |
| ITGA6 | integrin, alpha 6 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| LIF | leukemia inhibitory factor |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NCBP2 | nuclear cap binding protein subunit 2, 20kDa |
| NELL2 | NEL-like 2 (chicken) |
| NME1 | NME/NM23 nucleoside diphosphate kinase 1 |
| NOC3L | nucleolar complex associated 3 homolog (S. cerevisiae) |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 |
| NOP16 | NOP16 nucleolar protein |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| ODC1 | ornithine decarboxylase 1 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PLAUR | plasminogen activator, urokinase receptor |
| PNO1 | partner of NOB1 homolog (S. cerevisiae) |
| POLR2H | polymerase (RNA) II (DNA directed) polypeptide H |
| PPRC1 | peroxisome proliferator-activated receptor gamma, coactivator-related 1 |
| PRR7 | proline rich 7 (synaptic) |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| PUS7 | pseudouridylate synthase 7 (putative) |
| RGS2 | regulator of G-protein signaling 2 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| S100P | S100 calcium binding protein P |
| SEH1L | SEH1-like (S. cerevisiae) |
| SLC25A32 | solute carrier family 25 (mitochondrial folate carrier), member 32 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
| SNAI2 | snail family zinc finger 2 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| SRM | spermidine synthase |
| TFF1 | trefoil factor 1 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
| TRIB2 | tribbles pseudokinase 2 |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 |
| UCK2 | uridine-cytidine kinase 2 |
| WDR3 | WD repeat domain 3 |
| WDR43 | WD repeat domain 43 |
