| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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143 genes differentially expressed following the BRD-U44618005_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| AQP3 | aquaporin 3 (Gill blood group) |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide |
| BEX1 | brain expressed, X-linked 1 |
| C14ORF132 | chromosome 14 open reading frame 132 |
| CA2 | carbonic anhydrase II |
| CAPG | capping protein (actin filament), gelsolin-like |
| CFD | complement factor D (adipsin) |
| CHPT1 | choline phosphotransferase 1 |
| CLIC4 | chloride intracellular channel 4 |
| COCH | cochlin |
| CTSA | cathepsin A |
| CTSL | cathepsin L |
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 |
| CYBA | cytochrome b-245, alpha polypeptide |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DMBT1 | deleted in malignant brain tumors 1 |
| DUSP4 | dual specificity phosphatase 4 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FADS1 | fatty acid desaturase 1 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GLUL | glutamate-ammonia ligase |
| GNAS | GNAS complex locus |
| GPC3 | glypican 3 |
| IL17RB | interleukin 17 receptor B |
| IL2RG | interleukin 2 receptor, gamma |
| INSIG1 | insulin induced gene 1 |
| MAGEA12 | melanoma antigen family A12 |
| MAGEA3 | melanoma antigen family A3 |
| MAGEA6 | melanoma antigen family A6 |
| MAOB | monoamine oxidase B |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 |
| MAPT | microtubule-associated protein tau |
| MOXD1 | monooxygenase, DBH-like 1 |
| MT1G | metallothionein 1G |
| MT1H | metallothionein 1H |
| MT1X | metallothionein 1X |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming |
| NES | nestin |
| NFIL3 | nuclear factor, interleukin 3 regulated |
| NMU | neuromedin U |
| ODAM | odontogenic, ameloblast asssociated |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
| PEBP1 | phosphatidylethanolamine binding protein 1 |
| PHKA1 | phosphorylase kinase, alpha 1 (muscle) |
| PLIN2 | perilipin 2 |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| PRAME | preferentially expressed antigen in melanoma |
| PTGES | prostaglandin E synthase |
| RAB4A | RAB4A, member RAS oncogene family |
| RALGDS | ral guanine nucleotide dissociation stimulator |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 |
| RBP4 | retinol binding protein 4, plasma |
| RFX5 | regulatory factor X, 5 (influences HLA class II expression) |
| RPL37A | ribosomal protein L37a |
| SCCPDH | saccharopine dehydrogenase (putative) |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
| SFRP1 | secreted frizzled-related protein 1 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SRPX | sushi-repeat containing protein, X-linked |
| STAT1 | signal transducer and activator of transcription 1, 91kDa |
| SYNM | synemin, intermediate filament protein |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TMEM2 | transmembrane protein 2 |
| TNS1 | tensin 1 |
| TOX | thymocyte selection-associated high mobility group box |
| VAT1 | vesicle amine transport 1 |
| WFDC2 | WAP four-disulfide core domain 2 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 |
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| C6ORF62 | chromosome 6 open reading frame 62 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CAST | calpastatin |
| CCND1 | cyclin D1 |
| CD24 | CD24 molecule |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CLDN3 | claudin 3 |
| COL10A1 | collagen, type X, alpha 1 |
| CPA3 | carboxypeptidase A3 (mast cell) |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog |
| CTGF | connective tissue growth factor |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| CYTIP | cytohesin 1 interacting protein |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 |
| DLC1 | DLC1 Rho GTPase activating protein |
| DUSP6 | dual specificity phosphatase 6 |
| ENDOD1 | endonuclease domain containing 1 |
| EREG | epiregulin |
| FAM69A | family with sequence similarity 69, member A |
| FOSL1 | FOS-like antigen 1 |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 |
| GLIPR1 | GLI pathogenesis-related 1 |
| GMPR | guanosine monophosphate reductase |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 |
| HAT1 | histone acetyltransferase 1 |
| HES1 | hes family bHLH transcription factor 1 |
| HIST1H2BG | histone cluster 1, H2bg |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 |
| HMGA2 | high mobility group AT-hook 2 |
| IGF1 | insulin-like growth factor 1 (somatomedin C) |
| IGHM | immunoglobulin heavy constant mu |
| IGKV4-1 | immunoglobulin kappa variable 4-1 |
| JCHAIN | joining chain of multimeric IgA and IgM |
| KCTD12 | potassium channel tetramerization domain containing 12 |
| LAPTM4B | lysosomal protein transmembrane 4 beta |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| MMP10 | matrix metallopeptidase 10 |
| MMP9 | matrix metallopeptidase 9 |
| MRTO4 | mRNA turnover 4 homolog (S. cerevisiae) |
| OLFML2A | olfactomedin-like 2A |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase |
| PAWR | PRKC, apoptosis, WT1, regulator |
| PLXNC1 | plexin C1 |
| PMM2 | phosphomannomutase 2 |
| PON2 | paraoxonase 2 |
| PPL | periplakin |
| PRSS23 | protease, serine, 23 |
| RANBP1 | RAN binding protein 1 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) |
| S100A2 | S100 calcium binding protein A2 |
| SELENBP1 | selenium binding protein 1 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C |
| SFRP4 | secreted frizzled-related protein 4 |
| SMAD3 | SMAD family member 3 |
| SNAI2 | snail family zinc finger 2 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing |
| SPON1 | spondin 1, extracellular matrix protein |
| THBS1 | thrombospondin 1 |
| TLR4 | toll-like receptor 4 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TPM1 | tropomyosin 1 (alpha) |
| UBE3C | ubiquitin protein ligase E3C |
| VAMP8 | vesicle-associated membrane protein 8 |
| VCAN | versican |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 |
