Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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143 genes differentially expressed following the BRD-U44618005_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
A2M | alpha-2-macroglobulin |
AKAP12 | A kinase (PRKA) anchor protein 12 |
AQP3 | aquaporin 3 (Gill blood group) |
ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide |
BEX1 | brain expressed, X-linked 1 |
C14ORF132 | chromosome 14 open reading frame 132 |
CA2 | carbonic anhydrase II |
CAPG | capping protein (actin filament), gelsolin-like |
CFD | complement factor D (adipsin) |
CHPT1 | choline phosphotransferase 1 |
CLIC4 | chloride intracellular channel 4 |
COCH | cochlin |
CTSA | cathepsin A |
CTSL | cathepsin L |
CX3CL1 | chemokine (C-X3-C motif) ligand 1 |
CXCL14 | chemokine (C-X-C motif) ligand 14 |
CYBA | cytochrome b-245, alpha polypeptide |
DDIT4 | DNA-damage-inducible transcript 4 |
DMBT1 | deleted in malignant brain tumors 1 |
DUSP4 | dual specificity phosphatase 4 |
FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
FADS1 | fatty acid desaturase 1 |
GBP2 | guanylate binding protein 2, interferon-inducible |
GLUL | glutamate-ammonia ligase |
GNAS | GNAS complex locus |
GPC3 | glypican 3 |
IL17RB | interleukin 17 receptor B |
IL2RG | interleukin 2 receptor, gamma |
INSIG1 | insulin induced gene 1 |
MAGEA12 | melanoma antigen family A12 |
MAGEA3 | melanoma antigen family A3 |
MAGEA6 | melanoma antigen family A6 |
MAOB | monoamine oxidase B |
MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 |
MAPT | microtubule-associated protein tau |
MOXD1 | monooxygenase, DBH-like 1 |
MT1G | metallothionein 1G |
MT1H | metallothionein 1H |
MT1X | metallothionein 1X |
MUC5B | mucin 5B, oligomeric mucus/gel-forming |
NES | nestin |
NFIL3 | nuclear factor, interleukin 3 regulated |
NMU | neuromedin U |
ODAM | odontogenic, ameloblast asssociated |
PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
PEBP1 | phosphatidylethanolamine binding protein 1 |
PHKA1 | phosphorylase kinase, alpha 1 (muscle) |
PLIN2 | perilipin 2 |
PPAP2B | phosphatidic acid phosphatase type 2B |
PRAME | preferentially expressed antigen in melanoma |
PTGES | prostaglandin E synthase |
RAB4A | RAB4A, member RAS oncogene family |
RALGDS | ral guanine nucleotide dissociation stimulator |
RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 |
RBP4 | retinol binding protein 4, plasma |
RFX5 | regulatory factor X, 5 (influences HLA class II expression) |
RPL37A | ribosomal protein L37a |
SCCPDH | saccharopine dehydrogenase (putative) |
SCUBE2 | signal peptide, CUB domain, EGF-like 2 |
SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
SFRP1 | secreted frizzled-related protein 1 |
SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
SRPX | sushi-repeat containing protein, X-linked |
STAT1 | signal transducer and activator of transcription 1, 91kDa |
SYNM | synemin, intermediate filament protein |
TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
TMEM2 | transmembrane protein 2 |
TNS1 | tensin 1 |
TOX | thymocyte selection-associated high mobility group box |
VAT1 | vesicle amine transport 1 |
WFDC2 | WAP four-disulfide core domain 2 |
ZMIZ1 | zinc finger, MIZ-type containing 1 |
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
AMIGO2 | adhesion molecule with Ig-like domain 2 |
C6ORF62 | chromosome 6 open reading frame 62 |
CASP1 | caspase 1, apoptosis-related cysteine peptidase |
CAST | calpastatin |
CCND1 | cyclin D1 |
CD24 | CD24 molecule |
CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
CLDN3 | claudin 3 |
COL10A1 | collagen, type X, alpha 1 |
CPA3 | carboxypeptidase A3 (mast cell) |
CRK | v-crk avian sarcoma virus CT10 oncogene homolog |
CTGF | connective tissue growth factor |
CYR61 | cysteine-rich, angiogenic inducer, 61 |
CYTIP | cytohesin 1 interacting protein |
DKK3 | dickkopf WNT signaling pathway inhibitor 3 |
DLC1 | DLC1 Rho GTPase activating protein |
DUSP6 | dual specificity phosphatase 6 |
ENDOD1 | endonuclease domain containing 1 |
EREG | epiregulin |
FAM69A | family with sequence similarity 69, member A |
FOSL1 | FOS-like antigen 1 |
GADD45B | growth arrest and DNA-damage-inducible, beta |
GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 |
GLIPR1 | GLI pathogenesis-related 1 |
GMPR | guanosine monophosphate reductase |
GRIA2 | glutamate receptor, ionotropic, AMPA 2 |
HAT1 | histone acetyltransferase 1 |
HES1 | hes family bHLH transcription factor 1 |
HIST1H2BG | histone cluster 1, H2bg |
HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
HLA-DRA | major histocompatibility complex, class II, DR alpha |
HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 |
HMGA2 | high mobility group AT-hook 2 |
IGF1 | insulin-like growth factor 1 (somatomedin C) |
IGHM | immunoglobulin heavy constant mu |
IGKV4-1 | immunoglobulin kappa variable 4-1 |
JCHAIN | joining chain of multimeric IgA and IgM |
KCTD12 | potassium channel tetramerization domain containing 12 |
LAPTM4B | lysosomal protein transmembrane 4 beta |
MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 |
MMP10 | matrix metallopeptidase 10 |
MMP9 | matrix metallopeptidase 9 |
MRTO4 | mRNA turnover 4 homolog (S. cerevisiae) |
OLFML2A | olfactomedin-like 2A |
PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase |
PAWR | PRKC, apoptosis, WT1, regulator |
PLXNC1 | plexin C1 |
PMM2 | phosphomannomutase 2 |
PON2 | paraoxonase 2 |
PPL | periplakin |
PRSS23 | protease, serine, 23 |
RANBP1 | RAN binding protein 1 |
RBM3 | RNA binding motif (RNP1, RRM) protein 3 |
RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) |
S100A2 | S100 calcium binding protein A2 |
SELENBP1 | selenium binding protein 1 |
SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C |
SFRP4 | secreted frizzled-related protein 4 |
SMAD3 | SMAD family member 3 |
SNAI2 | snail family zinc finger 2 |
SORL1 | sortilin-related receptor, L(DLR class) A repeats containing |
SPON1 | spondin 1, extracellular matrix protein |
THBS1 | thrombospondin 1 |
TLR4 | toll-like receptor 4 |
TM4SF1 | transmembrane 4 L six family member 1 |
TPM1 | tropomyosin 1 (alpha) |
UBE3C | ubiquitin protein ligase E3C |
VAMP8 | vesicle-associated membrane protein 8 |
VCAN | versican |
ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 |