| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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228 genes differentially expressed following the BRD-U51024685_HG-6-64-01_HT29_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| AARS | alanyl-tRNA synthetase |
| ABHD4 | abhydrolase domain containing 4 |
| ACTN1 | actinin, alpha 1 |
| AIF1 | allograft inflammatory factor 1 |
| ALDOC | aldolase C, fructose-bisphosphate |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) |
| ANXA4 | annexin A4 |
| APOD | apolipoprotein D |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| ATF4 | activating transcription factor 4 |
| BASP1 | brain abundant, membrane attached signal protein 1 |
| BCL6 | B-cell CLL/lymphoma 6 |
| BEX1 | brain expressed, X-linked 1 |
| BEX4 | brain expressed, X-linked 4 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like |
| C1ORF115 | chromosome 1 open reading frame 115 |
| C6ORF48 | chromosome 6 open reading frame 48 |
| C9ORF3 | chromosome 9 open reading frame 3 |
| CBS | cystathionine-beta-synthase |
| CCDC92 | coiled-coil domain containing 92 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| COL11A1 | collagen, type XI, alpha 1 |
| CST3 | cystatin C |
| CTSB | cathepsin B |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DUSP10 | dual specificity phosphatase 10 |
| ELF1 | E74-like factor 1 (ets domain transcription factor) |
| ENPP4 | ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| FAM134B | family with sequence similarity 134, member B |
| FAM63A | family with sequence similarity 63, member A |
| FCGBP | Fc fragment of IgG binding protein |
| FOXO3 | forkhead box O3 |
| FOXO4 | forkhead box O4 |
| GABARAP | GABA(A) receptor-associated protein |
| GAS6 | growth arrest-specific 6 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 |
| GLRX | glutaredoxin (thioltransferase) |
| GOLGA8A | golgin A8 family, member A |
| GSN | gelsolin |
| H1F0 | H1 histone family, member 0 |
| HIST1H2AC | histone cluster 1, H2ac |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HMOX1 | heme oxygenase 1 |
| IDS | iduronate 2-sulfatase |
| IFI27 | interferon, alpha-inducible protein 27 |
| IRS2 | insulin receptor substrate 2 |
| ISG15 | ISG15 ubiquitin-like modifier |
| KLHL24 | kelch-like family member 24 |
| KRT7 | keratin 7, type II |
| LCN2 | lipocalin 2 |
| LRRC8D | leucine rich repeat containing 8 family, member D |
| LXN | latexin |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog |
| MAGEA3 | melanoma antigen family A3 |
| MAGEA6 | melanoma antigen family A6 |
| MFAP5 | microfibrillar associated protein 5 |
| MGST3 | microsomal glutathione S-transferase 3 |
| MME | membrane metallo-endopeptidase |
| MT1F | metallothionein 1F |
| MVP | major vault protein |
| MXI1 | MAX interactor 1, dimerization protein |
| NPC2 | Niemann-Pick disease, type C2 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| PDZK1 | PDZ domain containing 1 |
| PHGDH | phosphoglycerate dehydrogenase |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
| PINK1 | PTEN induced putative kinase 1 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PLCB4 | phospholipase C, beta 4 |
| PRSS8 | protease, serine, 8 |
| PRUNE2 | prune homolog 2 (Drosophila) |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 |
| PYCARD | PYD and CARD domain containing |
| QPCT | glutaminyl-peptide cyclotransferase |
| QPRT | quinolinate phosphoribosyltransferase |
| RAP1GAP | RAP1 GTPase activating protein |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 |
| RFX5 | regulatory factor X, 5 (influences HLA class II expression) |
| RPL39L | ribosomal protein L39-like |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SELENBP1 | selenium binding protein 1 |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A |
| SEPP1 | selenoprotein P, plasma, 1 |
| SESN1 | sestrin 1 |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SIDT2 | SID1 transmembrane family, member 2 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 |
| SLC22A18 | solute carrier family 22, member 18 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 |
| SLC44A4 | solute carrier family 44, member 4 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SPINT1 | serine peptidase inhibitor, Kunitz type 1 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 |
| STAB1 | stabilin 1 |
| STXBP2 | syntaxin binding protein 2 |
| TFF3 | trefoil factor 3 (intestinal) |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 |
| TPP1 | tripeptidyl peptidase I |
| TSC22D3 | TSC22 domain family, member 3 |
| TSPYL5 | TSPY-like 5 |
| TST | thiosulfate sulfurtransferase (rhodanese) |
| TUBA1A | tubulin, alpha 1a |
| TYROBP | TYRO protein tyrosine kinase binding protein |
| WDTC1 | WD and tetratricopeptide repeats 1 |
| WFDC2 | WAP four-disulfide core domain 2 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| YPEL5 | yippee-like 5 (Drosophila) |
| Symbol | Name |
|---|---|
| ABCE1 | ATP-binding cassette, sub-family E (OABP), member 1 |
| ADM | adrenomedullin |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E |
| ATAD2 | ATPase family, AAA domain containing 2 |
| BIRC5 | baculoviral IAP repeat containing 5 |
| BOP1 | block of proliferation 1 |
| CAV1 | caveolin 1, caveolae protein, 22kDa |
| CAV2 | caveolin 2 |
| CCL19 | chemokine (C-C motif) ligand 19 |
| CCNA2 | cyclin A2 |
| CCNF | cyclin F |
| CDC20 | cell division cycle 20 |
| CDC6 | cell division cycle 6 |
| CDK1 | cyclin-dependent kinase 1 |
| CENPU | centromere protein U |
| CEP57 | centrosomal protein 57kDa |
| CHEK2 | checkpoint kinase 2 |
| CNN3 | calponin 3, acidic |
| COL6A1 | collagen, type VI, alpha 1 |
| CSRP2 | cysteine and glycine-rich protein 2 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 |
| DBF4 | DBF4 zinc finger |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DNAJC9 | DnaJ (Hsp40) homolog, subfamily C, member 9 |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
| EIF4E | eukaryotic translation initiation factor 4E |
| EIF5A | eukaryotic translation initiation factor 5A |
| EREG | epiregulin |
| EXOSC4 | exosome component 4 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FEN1 | flap structure-specific endonuclease 1 |
| FOSL1 | FOS-like antigen 1 |
| FSCN1 | fascin actin-bundling protein 1 |
| GAL | galanin/GMAP prepropeptide |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A |
| HAT1 | histone acetyltransferase 1 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
| HMGB2 | high mobility group box 2 |
| HOPX | HOP homeobox |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 |
| HSPA8 | heat shock 70kDa protein 8 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IER3 | immediate early response 3 |
| IFI16 | interferon, gamma-inducible protein 16 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 |
| KIAA0020 | KIAA0020 |
| KIF20A | kinesin family member 20A |
| KRT17 | keratin 17, type I |
| LMNB2 | lamin B2 |
| LOXL1 | lysyl oxidase-like 1 |
| LTF | lactotransferrin |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) |
| MCM2 | minichromosome maintenance complex component 2 |
| MCM3 | minichromosome maintenance complex component 3 |
| MCM4 | minichromosome maintenance complex component 4 |
| MCM5 | minichromosome maintenance complex component 5 |
| MCM6 | minichromosome maintenance complex component 6 |
| MELK | maternal embryonic leucine zipper kinase |
| MRTO4 | mRNA turnover 4 homolog (S. cerevisiae) |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| MYCBP | MYC binding protein |
| NES | nestin |
| NME1 | NME/NM23 nucleoside diphosphate kinase 1 |
| NOC3L | nucleolar complex associated 3 homolog (S. cerevisiae) |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 |
| ODC1 | ornithine decarboxylase 1 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase |
| PAX5 | paired box 5 |
| PCNA | proliferating cell nuclear antigen |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PLK1 | polo-like kinase 1 |
| PNP | purine nucleoside phosphorylase |
| PPAT | phosphoribosyl pyrophosphate amidotransferase |
| PRF1 | perforin 1 (pore forming protein) |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| RANBP1 | RAN binding protein 1 |
| RFC2 | replication factor C (activator 1) 2, 40kDa |
| RRM1 | ribonucleotide reductase M1 |
| RRM2 | ribonucleotide reductase M2 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SFN | stratifin |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| SRM | spermidine synthase |
| SRP72 | signal recognition particle 72kDa |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) |
| TCL1A | T-cell leukemia/lymphoma 1A |
| TDO2 | tryptophan 2,3-dioxygenase |
| TK1 | thymidine kinase 1, soluble |
| TLR4 | toll-like receptor 4 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TPX2 | TPX2, microtubule-associated |
| TRIP13 | thyroid hormone receptor interactor 13 |
| TUBB2A | tubulin, beta 2A class IIa |
| TYMS | thymidylate synthetase |
| UBE2C | ubiquitin-conjugating enzyme E2C |
| UBE2S | ubiquitin-conjugating enzyme E2S |
| UCHL5 | ubiquitin carboxyl-terminal hydrolase L5 |
| VRK1 | vaccinia related kinase 1 |
| WNT5A | wingless-type MMTV integration site family, member 5A |
| WWTR1 | WW domain containing transcription regulator 1 |
