BRD-U60236422_WH-4-025_PC3_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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59 genes differentially expressed following the BRD-U60236422_WH-4-025_PC3_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
AGR2 anterior gradient 2
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CHRDL1 chordin-like 1
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CTTN cortactin
DDR1 discoidin domain receptor tyrosine kinase 1
DSP desmoplakin
FGB fibrinogen beta chain
GLS glutaminase
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HIST1H1C histone cluster 1, H1c
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
KLK11 kallikrein-related peptidase 11
KLRK1 killer cell lectin-like receptor subfamily K, member 1
LDOC1 leucine zipper, down-regulated in cancer 1
LGALS3 lectin, galactoside-binding, soluble, 3
MAMLD1 mastermind-like domain containing 1
MET MET proto-oncogene, receptor tyrosine kinase
SCGB2A2 secretoglobin, family 2A, member 2
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SEPP1 selenoprotein P, plasma, 1
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SIRT3 sirtuin 3
STAT4 signal transducer and activator of transcription 4
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TPD52L1 tumor protein D52-like 1
TSPAN13 tetraspanin 13
TSPAN8 tetraspanin 8

decreased expression

Symbol Name
AKT3 v-akt murine thymoma viral oncogene homolog 3
CCP110 centriolar coiled coil protein 110kDa
CDV3 CDV3 homolog (mouse)
COTL1 coactosin-like F-actin binding protein 1
DACH1 dachshund family transcription factor 1
EDNRB endothelin receptor type B
EIF5A eukaryotic translation initiation factor 5A
FBLN1 fibulin 1
FGFR3 fibroblast growth factor receptor 3
GAL galanin/GMAP prepropeptide
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IGFBP3 insulin-like growth factor binding protein 3
LEF1 lymphoid enhancer-binding factor 1
MFAP2 microfibrillar-associated protein 2
MMP3 matrix metallopeptidase 3
MYH10 myosin, heavy chain 10, non-muscle
NPTX2 neuronal pentraxin II
PLAC8 placenta-specific 8
RPN1 ribophorin I
RTN1 reticulon 1
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
SLC43A3 solute carrier family 43, member 3
SPAG1 sperm associated antigen 1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
USP6NL USP6 N-terminal like
ZBTB18 zinc finger and BTB domain containing 18