| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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211 genes differentially expressed following the BRD-U61997977_WZ-4-145_A375_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| AKAP13 | A kinase (PRKA) anchor protein 13 |
| ALDOC | aldolase C, fructose-bisphosphate |
| ATF3 | activating transcription factor 3 |
| BEX4 | brain expressed, X-linked 4 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| C14ORF1 | chromosome 14 open reading frame 1 |
| C14ORF132 | chromosome 14 open reading frame 132 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CES2 | carboxylesterase 2 |
| CRABP2 | cellular retinoic acid binding protein 2 |
| CYFIP2 | cytoplasmic FMR1 interacting protein 2 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) |
| DDB2 | damage-specific DNA binding protein 2, 48kDa |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 |
| DEFA5 | defensin, alpha 5, Paneth cell-specific |
| DHCR24 | 24-dehydrocholesterol reductase |
| DHCR7 | 7-dehydrocholesterol reductase |
| DUSP5 | dual specificity phosphatase 5 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 |
| EFNA1 | ephrin-A1 |
| EGR1 | early growth response 1 |
| FABP1 | fatty acid binding protein 1, liver |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 |
| FDPS | farnesyl diphosphate synthase |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GAS6 | growth arrest-specific 6 |
| GDF15 | growth differentiation factor 15 |
| GLS | glutaminase |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 |
| GPR137B | G protein-coupled receptor 137B |
| GRB7 | growth factor receptor-bound protein 7 |
| GRN | granulin |
| GSE1 | Gse1 coiled-coil protein |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HMOX1 | heme oxygenase 1 |
| HSD17B7 | hydroxysteroid (17-beta) dehydrogenase 7 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 |
| IER5 | immediate early response 5 |
| IGF1R | insulin-like growth factor 1 receptor |
| INSIG1 | insulin induced gene 1 |
| KDM5B | lysine (K)-specific demethylase 5B |
| KIAA0226L | KIAA0226-like |
| KIF5C | kinesin family member 5C |
| LDLR | low density lipoprotein receptor |
| LPIN1 | lipin 1 |
| LXN | latexin |
| MAB21L1 | mab-21-like 1 (C. elegans) |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog |
| MEIS1 | Meis homeobox 1 |
| MSMO1 | methylsterol monooxygenase 1 |
| MTMR11 | myotubularin related protein 11 |
| MTSS1 | metastasis suppressor 1 |
| MVP | major vault protein |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 |
| NOV | nephroblastoma overexpressed |
| NPC1 | Niemann-Pick disease, type C1 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| NRCAM | neuronal cell adhesion molecule |
| NRIP1 | nuclear receptor interacting protein 1 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| OSR2 | odd-skipped related transciption factor 2 |
| PEG3 | paternally expressed 3 |
| PEX11A | peroxisomal biogenesis factor 11 alpha |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PHYH | phytanoyl-CoA 2-hydroxylase |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLCB4 | phospholipase C, beta 4 |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) |
| PRUNE2 | prune homolog 2 (Drosophila) |
| RAB29 | RAB29, member RAS oncogene family |
| RIOK3 | RIO kinase 3 |
| RNMT | RNA (guanine-7-) methyltransferase |
| RPS27L | ribosomal protein S27-like |
| RRAGC | Ras-related GTP binding C |
| RRAGD | Ras-related GTP binding D |
| RTN2 | reticulon 2 |
| S100A11 | S100 calcium binding protein A11 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SERINC3 | serine incorporator 3 |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SLC16A6 | solute carrier family 16, member 6 |
| SLC22A18 | solute carrier family 22, member 18 |
| SLC25A4 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) |
| SQLE | squalene epoxidase |
| SQSTM1 | sequestosome 1 |
| TBX2 | T-box 2 |
| TFAP2B | transcription factor AP-2 beta (activating enhancer binding protein 2 beta) |
| TGIF1 | TGFB-induced factor homeobox 1 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| TP53 | tumor protein p53 |
| TPP1 | tripeptidyl peptidase I |
| WFDC1 | WAP four-disulfide core domain 1 |
| Symbol | Name |
|---|---|
| ADD3 | adducin 3 (gamma) |
| ANOS1 | anosmin 1 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B |
| ARNTL2 | aryl hydrocarbon receptor nuclear translocator-like 2 |
| ASF1B | anti-silencing function 1B histone chaperone |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) |
| AURKA | aurora kinase A |
| AURKB | aurora kinase B |
| BIRC5 | baculoviral IAP repeat containing 5 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| CCNA2 | cyclin A2 |
| CCNF | cyclin F |
| CD24 | CD24 molecule |
| CDC25A | cell division cycle 25A |
| CDC6 | cell division cycle 6 |
| CDK1 | cyclin-dependent kinase 1 |
| CENPA | centromere protein A |
| CENPF | centromere protein F, 350/400kDa |
| CEP55 | centrosomal protein 55kDa |
| COL3A1 | collagen, type III, alpha 1 |
| COL5A2 | collagen, type V, alpha 2 |
| COL6A2 | collagen, type VI, alpha 2 |
| CSTA | cystatin A (stefin A) |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DBF4 | DBF4 zinc finger |
| DHFR | dihydrofolate reductase |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 |
| DNAJC9 | DnaJ (Hsp40) homolog, subfamily C, member 9 |
| DPT | dermatopontin |
| DSCC1 | DNA replication and sister chromatid cohesion 1 |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| ECT2 | epithelial cell transforming 2 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| FBXO5 | F-box protein 5 |
| FEN1 | flap structure-specific endonuclease 1 |
| FOXM1 | forkhead box M1 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) |
| GINS3 | GINS complex subunit 3 (Psf3 homolog) |
| GTSE1 | G-2 and S-phase expressed 1 |
| H2AFV | H2A histone family, member V |
| HAL | histidine ammonia-lyase |
| HBB | hemoglobin, beta |
| HMGB1 | high mobility group box 1 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| IL1R2 | interleukin 1 receptor, type II |
| KCTD12 | potassium channel tetramerization domain containing 12 |
| KIF11 | kinesin family member 11 |
| KIF14 | kinesin family member 14 |
| KIF15 | kinesin family member 15 |
| KIF18B | kinesin family member 18B |
| KIF20A | kinesin family member 20A |
| KIF4A | kinesin family member 4A |
| KRT13 | keratin 13, type I |
| LBR | lamin B receptor |
| LMNB1 | lamin B1 |
| LMNB2 | lamin B2 |
| LPAR1 | lysophosphatidic acid receptor 1 |
| LTF | lactotransferrin |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) |
| MCM10 | minichromosome maintenance complex component 10 |
| MCM3 | minichromosome maintenance complex component 3 |
| MCM7 | minichromosome maintenance complex component 7 |
| MCUR1 | mitochondrial calcium uniporter regulator 1 |
| MKI67 | marker of proliferation Ki-67 |
| MMP12 | matrix metallopeptidase 12 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 |
| NCAPG | non-SMC condensin I complex, subunit G |
| NDC80 | NDC80 kinetochore complex component |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| NTS | neurotensin |
| NUSAP1 | nucleolar and spindle associated protein 1 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit |
| PSIP1 | PC4 and SFRS1 interacting protein 1 |
| RAD51AP1 | RAD51 associated protein 1 |
| RRM2 | ribonucleotide reductase M2 |
| S100A8 | S100 calcium binding protein A8 |
| SEPHS1 | selenophosphate synthetase 1 |
| SHCBP1 | SHC SH2-domain binding protein 1 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 |
| SMC2 | structural maintenance of chromosomes 2 |
| SMC4 | structural maintenance of chromosomes 4 |
| SPARCL1 | SPARC-like 1 (hevin) |
| SPC25 | SPC25, NDC80 kinetochore complex component |
| SRGN | serglycin |
| SSRP1 | structure specific recognition protein 1 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) |
| TACC3 | transforming, acidic coiled-coil containing protein 3 |
| TACSTD2 | tumor-associated calcium signal transducer 2 |
| TCF3 | transcription factor 3 |
| TCF4 | transcription factor 4 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| TIMELESS | timeless circadian clock |
| TMPO | thymopoietin |
| TOP2A | topoisomerase (DNA) II alpha 170kDa |
| TPX2 | TPX2, microtubule-associated |
| TUBB | tubulin, beta class I |
| UBE2C | ubiquitin-conjugating enzyme E2C |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 |
| WHSC1 | Wolf-Hirschhorn syndrome candidate 1 |
| YKT6 | YKT6 v-SNARE homolog (S. cerevisiae) |
