| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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195 genes differentially expressed following the BRD-U61997977_WZ-4-145_HCC515_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ADAM10 | ADAM metallopeptidase domain 10 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| AMACR | alpha-methylacyl-CoA racemase |
| ANXA4 | annexin A4 |
| BLVRB | biliverdin reductase B |
| C3 | complement component 3 |
| CA12 | carbonic anhydrase XII |
| CAPN1 | calpain 1, (mu/I) large subunit |
| CD46 | CD46 molecule, complement regulatory protein |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta |
| CFB | complement factor B |
| CLU | clusterin |
| CRYZ | crystallin, zeta (quinone reductase) |
| CTSA | cathepsin A |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
| DHCR24 | 24-dehydrocholesterol reductase |
| EFNA1 | ephrin-A1 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 |
| FGA | fibrinogen alpha chain |
| FGB | fibrinogen beta chain |
| FGG | fibrinogen gamma chain |
| FOLR1 | folate receptor 1 (adult) |
| FOXO4 | forkhead box O4 |
| FXYD3 | FXYD domain containing ion transport regulator 3 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 |
| GPC3 | glypican 3 |
| GPX3 | glutathione peroxidase 3 |
| GRN | granulin |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HMOX1 | heme oxygenase 1 |
| IFI27 | interferon, alpha-inducible protein 27 |
| KRT5 | keratin 5, type II |
| KYNU | kynureninase |
| LCN2 | lipocalin 2 |
| LEPROT | leptin receptor overlapping transcript |
| LGALS3 | lectin, galactoside-binding, soluble, 3 |
| MAGED2 | melanoma antigen family D2 |
| MEIS1 | Meis homeobox 1 |
| MPPED2 | metallophosphoesterase domain containing 2 |
| MSMO1 | methylsterol monooxygenase 1 |
| MTSS1 | metastasis suppressor 1 |
| MUC1 | mucin 1, cell surface associated |
| MVP | major vault protein |
| MXRA5 | matrix-remodelling associated 5 |
| MYL9 | myosin, light chain 9, regulatory |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NEU1 | sialidase 1 (lysosomal sialidase) |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 |
| PEG3 | paternally expressed 3 |
| PLD3 | phospholipase D family, member 3 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 |
| QPRT | quinolinate phosphoribosyltransferase |
| RBM47 | RNA binding motif protein 47 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| S100A14 | S100 calcium binding protein A14 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SEPP1 | selenoprotein P, plasma, 1 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 |
| SPATA20 | spermatogenesis associated 20 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| SQLE | squalene epoxidase |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) |
| SULT1A1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 |
| TACSTD2 | tumor-associated calcium signal transducer 2 |
| TGFBR3 | transforming growth factor, beta receptor III |
| TM7SF2 | transmembrane 7 superfamily member 2 |
| TPP1 | tripeptidyl peptidase I |
| TRIM29 | tripartite motif containing 29 |
| TSC22D1 | TSC22 domain family, member 1 |
| TTC39A | tetratricopeptide repeat domain 39A |
| TUG1 | taurine up-regulated 1 (non-protein coding) |
| UBXN4 | UBX domain protein 4 |
| UGDH | UDP-glucose 6-dehydrogenase |
| VAT1 | vesicle amine transport 1 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 |
| WDR45 | WD repeat domain 45 |
| XBP1 | X-box binding protein 1 |
| YBX3 | Y box binding protein 3 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 |
| ZNF91 | zinc finger protein 91 |
| Symbol | Name |
|---|---|
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E |
| ARL4C | ADP-ribosylation factor-like 4C |
| ASF1B | anti-silencing function 1B histone chaperone |
| ATAD2 | ATPase family, AAA domain containing 2 |
| AURKB | aurora kinase B |
| BIRC5 | baculoviral IAP repeat containing 5 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B |
| CACYBP | calcyclin binding protein |
| CCDC109B | coiled-coil domain containing 109B |
| CCNA2 | cyclin A2 |
| CCND1 | cyclin D1 |
| CCNE2 | cyclin E2 |
| CCNF | cyclin F |
| CCP110 | centriolar coiled coil protein 110kDa |
| CDC25A | cell division cycle 25A |
| CDC6 | cell division cycle 6 |
| CDCA3 | cell division cycle associated 3 |
| CDCA8 | cell division cycle associated 8 |
| CDK1 | cyclin-dependent kinase 1 |
| CENPA | centromere protein A |
| CENPE | centromere protein E, 312kDa |
| CENPU | centromere protein U |
| CEP55 | centrosomal protein 55kDa |
| DPYD | dihydropyrimidine dehydrogenase |
| DPYSL2 | dihydropyrimidinase-like 2 |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| DUSP6 | dual specificity phosphatase 6 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
| ESPL1 | extra spindle pole bodies homolog 1 (S. cerevisiae) |
| EXO1 | exonuclease 1 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit |
| FAM129A | family with sequence similarity 129, member A |
| FANCI | Fanconi anemia, complementation group I |
| FEN1 | flap structure-specific endonuclease 1 |
| FHL1 | four and a half LIM domains 1 |
| FOSL1 | FOS-like antigen 1 |
| GAL | galanin/GMAP prepropeptide |
| GBP1 | guanylate binding protein 1, interferon-inducible |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) |
| GPER1 | G protein-coupled estrogen receptor 1 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A |
| GTSE1 | G-2 and S-phase expressed 1 |
| HJURP | Holliday junction recognition protein |
| HMGB2 | high mobility group box 2 |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| JUN | jun proto-oncogene |
| KIF11 | kinesin family member 11 |
| KIF14 | kinesin family member 14 |
| KIF18B | kinesin family member 18B |
| KIF20A | kinesin family member 20A |
| KIF4A | kinesin family member 4A |
| LIG1 | ligase I, DNA, ATP-dependent |
| LMNB1 | lamin B1 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) |
| MCM10 | minichromosome maintenance complex component 10 |
| MCM3 | minichromosome maintenance complex component 3 |
| MELK | maternal embryonic leucine zipper kinase |
| MKI67 | marker of proliferation Ki-67 |
| MTHFD1 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 |
| NCAPG | non-SMC condensin I complex, subunit G |
| NCAPG2 | non-SMC condensin II complex, subunit G2 |
| NDC80 | NDC80 kinetochore complex component |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 |
| NUSAP1 | nucleolar and spindle associated protein 1 |
| OIP5 | Opa interacting protein 5 |
| PAQR4 | progestin and adipoQ receptor family member IV |
| PBK | PDZ binding kinase |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PLAC8 | placenta-specific 8 |
| PLK1 | polo-like kinase 1 |
| PMP22 | peripheral myelin protein 22 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit |
| PRC1 | protein regulator of cytokinesis 1 |
| PSMC3IP | PSMC3 interacting protein |
| RAD51 | RAD51 recombinase |
| RFC2 | replication factor C (activator 1) 2, 40kDa |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa |
| RRM2 | ribonucleotide reductase M2 |
| SAP30 | Sin3A-associated protein, 30kDa |
| SERTAD2 | SERTA domain containing 2 |
| SPC25 | SPC25, NDC80 kinetochore complex component |
| SRGN | serglycin |
| SYNM | synemin, intermediate filament protein |
| TACC3 | transforming, acidic coiled-coil containing protein 3 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 |
| TK1 | thymidine kinase 1, soluble |
| TMPO | thymopoietin |
| TNC | tenascin C |
| TOP2A | topoisomerase (DNA) II alpha 170kDa |
| TPX2 | TPX2, microtubule-associated |
| TRIP13 | thyroid hormone receptor interactor 13 |
| TUBA4A | tubulin, alpha 4a |
| TYMS | thymidylate synthetase |
| USP1 | ubiquitin specific peptidase 1 |
| WEE1 | WEE1 G2 checkpoint kinase |
| YKT6 | YKT6 v-SNARE homolog (S. cerevisiae) |
| ZWINT | ZW10 interacting kinetochore protein |
