| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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141 genes differentially expressed following the BRD-U64521890_XMD16-144_A375_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ADRB2 | adrenoceptor beta 2, surface |
| AFF1 | AF4/FMR2 family, member 1 |
| AHNAK2 | AHNAK nucleoprotein 2 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
| AREG | amphiregulin |
| ASS1 | argininosuccinate synthase 1 |
| C9ORF16 | chromosome 9 open reading frame 16 |
| CCDC92 | coiled-coil domain containing 92 |
| CCNF | cyclin F |
| CCNG2 | cyclin G2 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 |
| DSP | desmoplakin |
| DUSP14 | dual specificity phosphatase 14 |
| DUSP5 | dual specificity phosphatase 5 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| FABP4 | fatty acid binding protein 4, adipocyte |
| FDXR | ferredoxin reductase |
| FOLR1 | folate receptor 1 (adult) |
| GDF15 | growth differentiation factor 15 |
| GLS | glutaminase |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) |
| GPNMB | glycoprotein (transmembrane) nmb |
| GPX1 | glutathione peroxidase 1 |
| H2BFS | H2B histone family, member S (pseudogene) |
| HIST1H1C | histone cluster 1, H1c |
| HIST1H2AC | histone cluster 1, H2ac |
| HIST1H2AE | histone cluster 1, H2ae |
| HIST1H2BC | histone cluster 1, H2bc |
| HIST1H2BD | histone cluster 1, H2bd |
| HIST1H2BE | histone cluster 1, H2be |
| HIST1H2BF | histone cluster 1, H2bf |
| HIST1H2BH | histone cluster 1, H2bh |
| HIST1H2BK | histone cluster 1, H2bk |
| HIST1H3H | histone cluster 1, H3h |
| HIST1H4H | histone cluster 1, H4h |
| HIST2H2BE | histone cluster 2, H2be |
| IFI6 | interferon, alpha-inducible protein 6 |
| IL1RN | interleukin 1 receptor antagonist |
| ITGA6 | integrin, alpha 6 |
| JCHAIN | joining chain of multimeric IgA and IgM |
| KANK1 | KN motif and ankyrin repeat domains 1 |
| KDM5B | lysine (K)-specific demethylase 5B |
| KIF2C | kinesin family member 2C |
| KLHL21 | kelch-like family member 21 |
| KRCC1 | lysine-rich coiled-coil 1 |
| LGMN | legumain |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta |
| PLCB4 | phospholipase C, beta 4 |
| PROM1 | prominin 1 |
| RBKS | ribokinase |
| S100A8 | S100 calcium binding protein A8 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SESN1 | sestrin 1 |
| SGCB | sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) |
| SLC25A4 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 |
| STXBP1 | syntaxin binding protein 1 |
| TFF3 | trefoil factor 3 (intestinal) |
| TGFBR3 | transforming growth factor, beta receptor III |
| TM7SF2 | transmembrane 7 superfamily member 2 |
| TMEM2 | transmembrane protein 2 |
| TPD52L1 | tumor protein D52-like 1 |
| VAT1 | vesicle amine transport 1 |
| VAV3 | vav 3 guanine nucleotide exchange factor |
| ZFP36 | ZFP36 ring finger protein |
| Symbol | Name |
|---|---|
| AEBP1 | AE binding protein 1 |
| AFP | alpha-fetoprotein |
| AHR | aryl hydrocarbon receptor |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| BGN | biglycan |
| C3 | complement component 3 |
| CCNA2 | cyclin A2 |
| CD302 | CD302 molecule |
| CDC25A | cell division cycle 25A |
| CDC6 | cell division cycle 6 |
| CHEK1 | checkpoint kinase 1 |
| COL10A1 | collagen, type X, alpha 1 |
| COL1A1 | collagen, type I, alpha 1 |
| COL6A2 | collagen, type VI, alpha 2 |
| CP | ceruloplasmin (ferroxidase) |
| DCLK1 | doublecortin-like kinase 1 |
| DPYSL3 | dihydropyrimidinase-like 3 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| EXOSC8 | exosome component 8 |
| FKBP11 | FK506 binding protein 11, 19 kDa |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 |
| GSAP | gamma-secretase activating protein |
| IFITM3 | interferon induced transmembrane protein 3 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 |
| IGFBP7 | insulin-like growth factor binding protein 7 |
| KCTD12 | potassium channel tetramerization domain containing 12 |
| KRT17 | keratin 17, type I |
| LEF1 | lymphoid enhancer-binding factor 1 |
| MCM10 | minichromosome maintenance complex component 10 |
| MCM2 | minichromosome maintenance complex component 2 |
| MCM3 | minichromosome maintenance complex component 3 |
| MCM5 | minichromosome maintenance complex component 5 |
| MCM6 | minichromosome maintenance complex component 6 |
| MCM7 | minichromosome maintenance complex component 7 |
| MELK | maternal embryonic leucine zipper kinase |
| MOK | MOK protein kinase |
| MSLN | mesothelin |
| MT1M | metallothionein 1M |
| MUC16 | mucin 16, cell surface associated |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 |
| MYLK | myosin light chain kinase |
| PARP2 | poly (ADP-ribose) polymerase 2 |
| PCOLCE | procollagen C-endopeptidase enhancer |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 |
| PYCR1 | pyrroline-5-carboxylate reductase 1 |
| RAD51 | RAD51 recombinase |
| RAD51AP1 | RAD51 associated protein 1 |
| RFC4 | replication factor C (activator 1) 4, 37kDa |
| RPL10 | ribosomal protein L10 |
| RTN1 | reticulon 1 |
| S100A2 | S100 calcium binding protein A2 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 |
| SNX10 | sorting nexin 10 |
| SORBS2 | sorbin and SH3 domain containing 2 |
| SORBS3 | sorbin and SH3 domain containing 3 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 |
| TACSTD2 | tumor-associated calcium signal transducer 2 |
| TLR4 | toll-like receptor 4 |
| TMEM176A | transmembrane protein 176A |
| TMEM176B | transmembrane protein 176B |
| TRIP13 | thyroid hormone receptor interactor 13 |
| VGLL1 | vestigial-like family member 1 |
