BRD-U70626184_BI-2536_HEPG2_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

60 genes differentially expressed following the BRD-U70626184_BI-2536_HEPG2_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACAT2 acetyl-CoA acetyltransferase 2
AKR1C1 aldo-keto reductase family 1, member C1
ALDOC aldolase C, fructose-bisphosphate
ANXA3 annexin A3
ANXA6 annexin A6
ASNS asparagine synthetase (glutamine-hydrolyzing)
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EGFL6 EGF-like-domain, multiple 6
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ELOVL6 ELOVL fatty acid elongase 6
FAM69A family with sequence similarity 69, member A
FDFT1 farnesyl-diphosphate farnesyltransferase 1
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HOMER2 homer scaffolding protein 2
IFI44L interferon-induced protein 44-like
IGKC immunoglobulin kappa constant
KDM5D lysine (K)-specific demethylase 5D
LYZ lysozyme
MEIS1 Meis homeobox 1
MSMO1 methylsterol monooxygenase 1
NRIP1 nuclear receptor interacting protein 1
PHYH phytanoyl-CoA 2-hydroxylase
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
RGS1 regulator of G-protein signaling 1
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SFN stratifin
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SQSTM1 sequestosome 1
TMEM97 transmembrane protein 97
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
WFDC2 WAP four-disulfide core domain 2

decreased expression

Symbol Name
ACAA2 acetyl-CoA acyltransferase 2
ADM adrenomedullin
CA12 carbonic anhydrase XII
CXCL14 chemokine (C-X-C motif) ligand 14
E2F2 E2F transcription factor 2
EPAS1 endothelial PAS domain protein 1
EXOSC4 exosome component 4
GAL galanin/GMAP prepropeptide
GJA1 gap junction protein, alpha 1, 43kDa
INHBB inhibin, beta B
IPO13 importin 13
ITGA6 integrin, alpha 6
KLK10 kallikrein-related peptidase 10
NDRG1 N-myc downstream regulated 1
NMU neuromedin U
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PDZK1IP1 PDZK1 interacting protein 1
PI3 peptidase inhibitor 3, skin-derived
S100A7 S100 calcium binding protein A7
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
TGFBI transforming growth factor, beta-induced, 68kDa
TOP2A topoisomerase (DNA) II alpha 170kDa
XIST X inactive specific transcript (non-protein coding)
ZFP36L2 ZFP36 ring finger protein-like 2
ZMYM2 zinc finger, MYM-type 2
Funding