BRD-U73238814_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

58 genes differentially expressed following the BRD-U73238814_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRG2 adhesion G protein-coupled receptor G2
AEBP1 AE binding protein 1
AKR1C2 aldo-keto reductase family 1, member C2
BTG2 BTG family, member 2
CA12 carbonic anhydrase XII
CAPG capping protein (actin filament), gelsolin-like
CD40 CD40 molecule, TNF receptor superfamily member 5
CD99 CD99 molecule
CECR1 cat eye syndrome chromosome region, candidate 1
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
COL10A1 collagen, type X, alpha 1
COL5A1 collagen, type V, alpha 1
CPE carboxypeptidase E
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
DCN decorin
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
FMOD fibromodulin
HBB hemoglobin, beta
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MGP matrix Gla protein
MMP11 matrix metallopeptidase 11
MT1M metallothionein 1M
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PBX1 pre-B-cell leukemia homeobox 1
PEG3 paternally expressed 3
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PTGIS prostaglandin I2 (prostacyclin) synthase
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RGCC regulator of cell cycle
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SULF1 sulfatase 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10

decreased expression

Symbol Name
AKAP12 A kinase (PRKA) anchor protein 12
BZW2 basic leucine zipper and W2 domains 2
CCNB1 cyclin B1
CCND1 cyclin D1
CSTA cystatin A (stefin A)
ENOPH1 enolase-phosphatase 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FST follistatin
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1
IGFBP3 insulin-like growth factor binding protein 3
IL13RA2 interleukin 13 receptor, alpha 2
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MCOLN1 mucolipin 1
MOK MOK protein kinase
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPRK protein tyrosine phosphatase, receptor type, K
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
STK39 serine threonine kinase 39
TMEM47 transmembrane protein 47
TSPAN13 tetraspanin 13
Funding