Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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53 genes differentially expressed following the BRD-U74615290_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
CAV1 | caveolin 1, caveolae protein, 22kDa |
CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 |
CTGF | connective tissue growth factor |
DEFA4 | defensin, alpha 4, corticostatin |
EMP1 | epithelial membrane protein 1 |
FHOD3 | formin homology 2 domain containing 3 |
HBEGF | heparin-binding EGF-like growth factor |
HIST1H1C | histone cluster 1, H1c |
HIST1H2AC | histone cluster 1, H2ac |
IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 |
JAG1 | jagged 1 |
MXRA5 | matrix-remodelling associated 5 |
OLFM4 | olfactomedin 4 |
RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
SCG2 | secretogranin II |
SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
SST | somatostatin |
TAGLN | transgelin |
TBX3 | T-box 3 |
THBS1 | thrombospondin 1 |
Symbol | Name |
---|---|
ATF5 | activating transcription factor 5 |
BCAS3 | breast carcinoma amplified sequence 3 |
BPTF | bromodomain PHD finger transcription factor |
CD58 | CD58 molecule |
CKS2 | CDC28 protein kinase regulatory subunit 2 |
FBP1 | fructose-1,6-bisphosphatase 1 |
FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) |
GABPB1 | GA binding protein transcription factor, beta subunit 1 |
GTPBP8 | GTP-binding protein 8 (putative) |
HIST1H4C | histone cluster 1, H4c |
HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
HMG20B | high mobility group 20B |
HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
HN1 | hematological and neurological expressed 1 |
HOPX | HOP homeobox |
HOXA5 | homeobox A5 |
HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
IDI1 | isopentenyl-diphosphate delta isomerase 1 |
INSIG1 | insulin induced gene 1 |
JMJD6 | jumonji domain containing 6 |
LAT2 | linker for activation of T cells family, member 2 |
MBP | myelin basic protein |
ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
MSMO1 | methylsterol monooxygenase 1 |
MYH10 | myosin, heavy chain 10, non-muscle |
NUP85 | nucleoporin 85kDa |
PARP2 | poly (ADP-ribose) polymerase 2 |
PHACTR2 | phosphatase and actin regulator 2 |
PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 |
SGK1 | serum/glucocorticoid regulated kinase 1 |
TUBD1 | tubulin, delta 1 |
UBE3B | ubiquitin protein ligase E3B |