| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | bromodomain containing 4|The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 23476) |
| External Link | https://ncbi.nlm.nih.gov/gene/23476 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the BRD4 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HIST1H2BK | histone cluster 1, H2bk | 0.0144788 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.0140428 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 0.0134712 |
| HIST1H2AC | histone cluster 1, H2ac | 0.0131184 |
| H1-2 | H1.2 linker histone, cluster member | 0.0127751 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0122265 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 | 0.010709 |
| MAMLD1 | mastermind-like domain containing 1 | 0.0106697 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.010265 |
| HIST1H2BD | histone cluster 1, H2bd | 0.0101 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | 0.00990903 |
| PEG10 | paternally expressed 10 | 0.00968358 |
| TST | thiosulfate sulfurtransferase (rhodanese) | 0.00944806 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.00936122 |
| SPON1 | spondin 1, extracellular matrix protein | 0.00911313 |
| EFHD1 | EF-hand domain family, member D1 | 0.00908677 |
| COTL1 | coactosin-like F-actin binding protein 1 | 0.00893842 |
| KRT19 | keratin 19, type I | 0.00881631 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.00857532 |
| PROM1 | prominin 1 | 0.00855189 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | 0.00853688 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | 0.00845739 |
| PEG3 | paternally expressed 3 | 0.00843456 |
| AMOTL2 | angiomotin like 2 | 0.00819885 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.00817721 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.00812309 |
| PALLD | palladin, cytoskeletal associated protein | 0.00811243 |
| AGRN | agrin | 0.00804617 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.00801927 |
| KAZN | kazrin, periplakin interacting protein | 0.00799211 |
| LHFP | lipoma HMGIC fusion partner | 0.00797548 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | 0.00795699 |
| TSPAN4 | tetraspanin 4 | 0.00791997 |
| TNNT1 | troponin T type 1 (skeletal, slow) | 0.00789812 |
| TGM2 | transglutaminase 2 | 0.0078764 |
| RGS10 | regulator of G-protein signaling 10 | 0.0078032 |
| IER5 | immediate early response 5 | 0.00779758 |
| DHCR24 | 24-dehydrocholesterol reductase | 0.00763597 |
| GAS6 | growth arrest-specific 6 | 0.00763428 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.00761538 |
| PNMA1 | paraneoplastic Ma antigen 1 | 0.00760984 |
| CCDC92 | coiled-coil domain containing 92 | 0.00760671 |
| RTN3 | reticulon 3 | 0.00759238 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 0.00757101 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | 0.00751245 |
| NXN | nucleoredoxin | 0.00748011 |
| MYH10 | myosin, heavy chain 10, non-muscle | 0.00747774 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | 0.00738479 |
| SIRT3 | sirtuin 3 | 0.00735376 |
| MYO6 | myosin VI | 0.00728932 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.00719677 |
| HIST1H2BH | histone cluster 1, H2bh | 0.00719381 |
| HIST2H2BE | histone cluster 2, H2be | 0.00717496 |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing | 0.00714965 |
| C14ORF132 | chromosome 14 open reading frame 132 | 0.00707311 |
| ACSF2 | acyl-CoA synthetase family member 2 | 0.00706812 |
| CCN2 | cellular communication network factor 2 | 0.00706112 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.00704596 |
| FAM171A1 | family with sequence similarity 171, member A1 | 0.00700608 |
| MATN2 | matrilin 2 | 0.00699306 |
| TUBB2B | tubulin, beta 2B class IIb | 0.00694719 |
| NEU1 | sialidase 1 (lysosomal sialidase) | 0.00694089 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | 0.00689471 |
| KRCC1 | lysine-rich coiled-coil 1 | 0.00685524 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | 0.00678253 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | 0.00674941 |
| PFKL | phosphofructokinase, liver | 0.00672666 |
| PSIP1 | PC4 and SFRS1 interacting protein 1 | 0.00670958 |
| VAMP8 | vesicle-associated membrane protein 8 | 0.00668122 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.00667292 |
| EGR2 | early growth response 2 | 0.00666333 |
| GSDME | gasdermin E | 0.00666009 |
| PLLP | plasmolipin | 0.00662199 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.00661611 |
| CDR2L | cerebellar degeneration-related protein 2-like | 0.00661481 |
| GATA3 | GATA binding protein 3 | 0.00661119 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 0.00659339 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.00658278 |
| GSN | gelsolin | 0.00658236 |
| ERLIN2 | ER lipid raft associated 2 | 0.0065804 |
| TJP2 | tight junction protein 2 | 0.0065612 |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | 0.00656118 |
| EPS8L2 | EPS8-like 2 | 0.00652659 |
| CELSR2 | cadherin, EGF LAG seven-pass G-type receptor 2 | 0.00651435 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.00651382 |
| MRPS16 | mitochondrial ribosomal protein S16 | 0.00649748 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.00647048 |
| HTRA1 | HtrA serine peptidase 1 | 0.00644659 |
| KRT7 | keratin 7, type II | 0.00639913 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.00639607 |
| COBL | cordon-bleu WH2 repeat protein | 0.0063682 |
| G0S2 | G0/G1 switch 2 | 0.00629374 |
| WWC1 | WW and C2 domain containing 1 | 0.00629345 |
| NCAN | neurocan | 0.00629186 |
| SQSTM1 | sequestosome 1 | 0.00628843 |
| FUCA1 | fucosidase, alpha-L- 1, tissue | 0.00628578 |
| SLC22A18 | solute carrier family 22, member 18 | 0.00626803 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.00625356 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.00625125 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | 0.00624856 |
| NUAK1 | NUAK family, SNF1-like kinase, 1 | 0.00624315 |
| SEC14L1 | SEC14-like 1 (S. cerevisiae) | 0.00623694 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.00621176 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 | 0.00616324 |
| CLDN10 | claudin 10 | 0.00615817 |
| KRT18 | keratin 18, type I | 0.006152 |
| MAPK9 | mitogen-activated protein kinase 9 | 0.00614607 |
| SGCE | sarcoglycan, epsilon | 0.00614232 |
| FXYD6 | FXYD domain containing ion transport regulator 6 | 0.00613661 |
| ABLIM1 | actin binding LIM protein 1 | 0.0061232 |
| S100A10 | S100 calcium binding protein A10 | 0.00612204 |
| ADCY9 | adenylate cyclase 9 | 0.00610914 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | 0.00610346 |
| TNS3 | tensin 3 | 0.00609078 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.00607454 |
| OLIG2 | oligodendrocyte lineage transcription factor 2 | 0.00606012 |
| TXNRD1 | thioredoxin reductase 1 | 0.00605561 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.00602328 |
| FAM107A | family with sequence similarity 107, member A | 0.00597547 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | 0.00596369 |
| IQCE | IQ motif containing E | 0.00595529 |
| WWC3 | WWC family member 3 | 0.00595157 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 | 0.00595064 |
| IRF8 | interferon regulatory factor 8 | 0.00594946 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.00592124 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.00589694 |
| PDZK1 | PDZ domain containing 1 | 0.00587054 |
| CES1 | carboxylesterase 1 | 0.00585402 |
| ATMIN | ATM interactor | 0.00585342 |
| RGCC | regulator of cell cycle | 0.0058183 |
| TTC39A | tetratricopeptide repeat domain 39A | 0.00580007 |
| MCCC1 | methylcrotonoyl-CoA carboxylase 1 (alpha) | 0.00577872 |
| SRR | serine racemase | 0.00576861 |
| TBC1D12 | TBC1 domain family, member 12 | 0.00576144 |
| KRT8 | keratin 8, type II | 0.00575805 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | 0.00571962 |
| EPCAM | epithelial cell adhesion molecule | 0.00570809 |
| DTX4 | deltex 4, E3 ubiquitin ligase | 0.00567521 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.00565613 |
| BLNK | B-cell linker | 0.00564571 |
| LZTFL1 | leucine zipper transcription factor-like 1 | 0.00564045 |
| PCGF2 | polycomb group ring finger 2 | 0.00562566 |
| SFRP4 | secreted frizzled-related protein 4 | 0.00559264 |
| DIPK1A | divergent protein kinase domain 1A | 0.00557597 |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) | 0.00555276 |
| DOCK9 | dedicator of cytokinesis 9 | 0.00554918 |
| SIK1 | salt-inducible kinase 1 | 0.00554389 |
| EHD1 | EH-domain containing 1 | 0.0055411 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | 0.00554097 |
| CYBA | cytochrome b-245, alpha polypeptide | 0.0055403 |
| ZCCHC14 | zinc finger, CCHC domain containing 14 | 0.00552772 |
| PLAT | plasminogen activator, tissue | 0.00552476 |
| EHD2 | EH-domain containing 2 | 0.00550132 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0054934 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | 0.00547741 |
| CLGN | calmegin | 0.00547555 |
| ANXA2 | annexin A2 | 0.00547068 |
| ABHD4 | abhydrolase domain containing 4 | 0.00546358 |
| MXRA7 | matrix-remodelling associated 7 | 0.00545919 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | 0.00544871 |
| MYRF | myelin regulatory factor | 0.00543851 |
| RRBP1 | ribosome binding protein 1 | 0.00543191 |
| MICB | MHC class I polypeptide-related sequence B | 0.00542975 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.00542393 |
| SYT17 | synaptotagmin XVII | 0.00542347 |
| TALDO1 | transaldolase 1 | 0.00540471 |
| COG4 | component of oligomeric golgi complex 4 | 0.00539729 |
| TRAPPC6A | trafficking protein particle complex 6A | 0.00537662 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.00537033 |
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | 0.00536014 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.00535346 |
| HMGCL | 3-hydroxymethyl-3-methylglutaryl-CoA lyase | 0.00534179 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.00534023 |
| PLAU | plasminogen activator, urokinase | 0.00532818 |
| DALRD3 | DALR anticodon binding domain containing 3 | 0.00532801 |
| FADS3 | fatty acid desaturase 3 | 0.00531179 |
| TUBA1A | tubulin, alpha 1a | 0.00530254 |
| NBEA | neurobeachin | 0.00530163 |
| IQCK | IQ motif containing K | 0.005292 |
| NAA40 | N(alpha)-acetyltransferase 40, NatD catalytic subunit | 0.00528694 |
| MYO5C | myosin VC | 0.00526303 |
| VCAM1 | vascular cell adhesion molecule 1 | 0.00525601 |
| IRX5 | iroquois homeobox 5 | 0.00525298 |
| SYNJ2 | synaptojanin 2 | 0.00524876 |
| MUC16 | mucin 16, cell surface associated | 0.00524424 |
| HMGA1 | high mobility group AT-hook 1 | 0.00524098 |
| NRCAM | neuronal cell adhesion molecule | 0.00521238 |
| LOC283683 | uncharacterized LOC283683 | 0.00519302 |
| ASXL2 | additional sex combs like transcriptional regulator 2 | 0.00519041 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.00518909 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.00518818 |
| LEPR | leptin receptor | 0.00518488 |
| FADS1 | fatty acid desaturase 1 | 0.00517977 |
| STX3 | syntaxin 3 | 0.00516774 |
| TUBB2A | tubulin, beta 2A class IIa | 0.00516071 |
| BACE1 | beta-site APP-cleaving enzyme 1 | 0.00515616 |
| SPINT1 | serine peptidase inhibitor, Kunitz type 1 | 0.0051408 |
| IRS1 | insulin receptor substrate 1 | 0.00513949 |
| TRAF3 | TNF receptor-associated factor 3 | 0.00513631 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.00513616 |
| EGR1 | early growth response 1 | 0.00513019 |
| VCL | vinculin | 0.00512964 |
| MAPT | microtubule-associated protein tau | 0.00512931 |
| TRIB2 | tribbles pseudokinase 2 | 0.00512469 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 0.00510486 |
| SIDT2 | SID1 transmembrane family, member 2 | 0.00510405 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.00510121 |
| CACNG4 | calcium channel, voltage-dependent, gamma subunit 4 | 0.00507566 |
| NID2 | nidogen 2 (osteonidogen) | 0.0050748 |
| MGAT4B | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B | 0.00507083 |
| ZCCHC24 | zinc finger, CCHC domain containing 24 | 0.00506287 |
| OMG | oligodendrocyte myelin glycoprotein | 0.00505685 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | 0.00505654 |
| ABCA3 | ATP-binding cassette, sub-family A (ABC1), member 3 | 0.00504524 |
| OPN3 | opsin 3 | 0.00504425 |
| ATP7B | ATPase, Cu++ transporting, beta polypeptide | 0.00503036 |
| ASRGL1 | asparaginase like 1 | 0.00502396 |
| MYOF | myoferlin | 0.00500774 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.00500467 |
| SCAND1 | SCAN domain containing 1 | 0.00498364 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | 0.00498013 |
| CPB1 | carboxypeptidase B1 (tissue) | 0.00496325 |
| WWOX | WW domain containing oxidoreductase | 0.00493604 |
| ABAT | 4-aminobutyrate aminotransferase | 0.00493404 |
| PKP4 | plakophilin 4 | 0.00493153 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.00492805 |
| JAK1 | Janus kinase 1 | 0.00492334 |
| DPYSL4 | dihydropyrimidinase-like 4 | 0.00491029 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0049055 |
| GPR137B | G protein-coupled receptor 137B | 0.00489885 |
| TSPAN1 | tetraspanin 1 | 0.0048967 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 | 0.004885 |
| SHTN1 | shootin 1 | 0.00488155 |
| TEX2 | testis expressed 2 | 0.00487918 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0048738 |
| OBSL1 | obscurin-like 1 | 0.00486832 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.00486663 |
| MUC4 | mucin 4, cell surface associated | 0.0048627 |
| C1QL1 | complement component 1, q subcomponent-like 1 | 0.00486021 |
| CLDN8 | claudin 8 | 0.00485537 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | 0.00485087 |
| G6PD | glucose-6-phosphate dehydrogenase | 0.00484725 |
| HIST3H2A | histone cluster 3, H2a | 0.00483345 |
| CLIP3 | CAP-GLY domain containing linker protein 3 | 0.00483008 |
| HACD1 | 3-hydroxyacyl-CoA dehydratase 1 | 0.0048252 |
| SAC3D1 | SAC3 domain containing 1 | 0.00481533 |
| SPAG16 | sperm associated antigen 16 | 0.00481101 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.00480555 |
| PXDC1 | PX domain containing 1 | 0.004805 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.00480143 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MAGEA3 | melanoma antigen family A3 | -0.0148951 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.012227 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.0119633 |
| CSTA | cystatin A (stefin A) | -0.011588 |
| LTF | lactotransferrin | -0.0110875 |
| JCHAIN | joining chain of multimeric IgA and IgM | -0.0107205 |
| MAGEA12 | melanoma antigen family A12 | -0.010591 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.0103745 |
| XIC | X chromosome inactivation center | -0.00957236 |
| CALML5 | calmodulin-like 5 | -0.00938089 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.00930334 |
| TPM4 | tropomyosin 4 | -0.00910563 |
| ITGA6 | integrin, alpha 6 | -0.00893626 |
| PLBD1 | phospholipase B domain containing 1 | -0.00885239 |
| RPL10 | ribosomal protein L10 | -0.00884634 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.00874843 |
| PLIN2 | perilipin 2 | -0.00861691 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | -0.00860966 |
| HOXB6 | homeobox B6 | -0.00838995 |
| CCN3 | cellular communication network factor 3 | -0.00831919 |
| ARG1 | arginase 1 | -0.008132 |
| S100A8 | S100 calcium binding protein A8 | -0.00805772 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.00796569 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | -0.00787043 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | -0.00779442 |
| PLN | phospholamban | -0.00777552 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.00771762 |
| CYTIP | cytohesin 1 interacting protein | -0.00765178 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | -0.00761566 |
| IL13RA2 | interleukin 13 receptor, alpha 2 | -0.00757062 |
| MSX1 | msh homeobox 1 | -0.00754678 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | -0.0074794 |
| NIBAN1 | niban apoptosis regulator 1 | -0.00745926 |
| S100P | S100 calcium binding protein P | -0.0074294 |
| CD163 | CD163 molecule | -0.00734032 |
| LUM | lumican | -0.007289 |
| MRPL42 | mitochondrial ribosomal protein L42 | -0.00724151 |
| EIF5 | eukaryotic translation initiation factor 5 | -0.0071988 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | -0.00714233 |
| MAGEA1 | melanoma antigen family A1 | -0.007117 |
| LY6D | lymphocyte antigen 6 complex, locus D | -0.00708873 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | -0.00707829 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | -0.00704207 |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 | -0.00702649 |
| HOPX | HOP homeobox | -0.00700194 |
| HOXB7 | homeobox B7 | -0.00699265 |
| KRT6A | keratin 6A, type II | -0.00697695 |
| ZNF91 | zinc finger protein 91 | -0.00689769 |
| CDC20 | cell division cycle 20 | -0.00675258 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.00673271 |
| ADI1 | acireductone dioxygenase 1 | -0.00669851 |
| TMEM45A | transmembrane protein 45A | -0.00668403 |
| S100A12 | S100 calcium binding protein A12 | -0.00664934 |
| FABP6 | fatty acid binding protein 6, ileal | -0.00663504 |
| ZNF430 | zinc finger protein 430 | -0.00661898 |
| DSC1 | desmocollin 1 | -0.00660372 |
| RPS5 | ribosomal protein S5 | -0.00658617 |
| ADM | adrenomedullin | -0.00654321 |
| SPRR1B | small proline-rich protein 1B | -0.00651214 |
| HOXB2 | homeobox B2 | -0.0064929 |
| ZNF44 | zinc finger protein 44 | -0.00646036 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.00639208 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0063823 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.00636051 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.00634641 |
| AQP3 | aquaporin 3 (Gill blood group) | -0.00631283 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.00628215 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) | -0.00626915 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase | -0.00624848 |
| TGFBR3 | transforming growth factor, beta receptor III | -0.00621727 |
| LYZ | lysozyme | -0.00618993 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.00611289 |
| C1QA | complement component 1, q subcomponent, A chain | -0.00611012 |
| S100A9 | S100 calcium binding protein A9 | -0.00609209 |
| BCHE | butyrylcholinesterase | -0.00608885 |
| SELENBP1 | selenium binding protein 1 | -0.00607713 |
| C4BPA | complement component 4 binding protein, alpha | -0.00605353 |
| EPHX3 | epoxide hydrolase 3 | -0.00598859 |
| LPAR6 | lysophosphatidic acid receptor 6 | -0.00596707 |
| PRAME | preferentially expressed antigen in melanoma | -0.00596341 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.00595387 |
| STAB1 | stabilin 1 | -0.00593112 |
| AQP9 | aquaporin 9 | -0.00591499 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | -0.00587276 |
| KRT16 | keratin 16, type I | -0.00587046 |
| MAGEA4 | melanoma antigen family A4 | -0.0058673 |
| IVL | involucrin | -0.00586561 |
| ZNF750 | zinc finger protein 750 | -0.00585723 |
| CTSG | cathepsin G | -0.00584857 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0058379 |
| NEFM | neurofilament, medium polypeptide | -0.00582758 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | -0.00582576 |
| HAS2 | hyaluronan synthase 2 | -0.00578635 |
| RGS4 | regulator of G-protein signaling 4 | -0.00575362 |
| KRT1 | keratin 1, type II | -0.00575027 |
| MAGEA11 | melanoma antigen family A11 | -0.00574998 |
| MPZL2 | myelin protein zero-like 2 | -0.00573807 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.00572137 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0057199 |
| IFI44 | interferon-induced protein 44 | -0.00570602 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | -0.00568782 |
| KLF2 | Kruppel-like factor 2 | -0.00563946 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like | -0.00562295 |
| SMAGP | small cell adhesion glycoprotein | -0.00561627 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.00560425 |
| DSG1 | desmoglein 1 | -0.00558956 |
| ZNF207 | zinc finger protein 207 | -0.00558729 |
| SLC38A2 | solute carrier family 38, member 2 | -0.00555886 |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 | -0.00555377 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | -0.00554764 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | -0.00554223 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.00553528 |
| ITK | IL2-inducible T-cell kinase | -0.00553221 |
| CD14 | CD14 molecule | -0.00553211 |
| SLC25A46 | solute carrier family 25, member 46 | -0.00553067 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | -0.00552483 |
| EDNRB | endothelin receptor type B | -0.00547645 |
| RNASE3 | ribonuclease, RNase A family, 3 | -0.00547002 |
| ERGIC2 | ERGIC and golgi 2 | -0.00546847 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -0.00545314 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -0.00538836 |
| HMG20B | high mobility group 20B | -0.00536835 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | -0.00535863 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.00535318 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | -0.0053363 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | -0.00532839 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | -0.00529455 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.00528306 |
| POF1B | premature ovarian failure, 1B | -0.0052676 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | -0.00526273 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.00526057 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.00523912 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | -0.00522521 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.00521492 |
| MPO | myeloperoxidase | -0.0052089 |
| KRT2 | keratin 2, type II | -0.00518801 |
| DEFA4 | defensin, alpha 4, corticostatin | -0.00518115 |
| LEF1 | lymphoid enhancer-binding factor 1 | -0.00517595 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | -0.00516038 |
| GPR171 | G protein-coupled receptor 171 | -0.00513441 |
| MAP3K7CL | MAP3K7 C-terminal like | -0.00512991 |
| PCP4 | Purkinje cell protein 4 | -0.0051278 |
| IL33 | interleukin 33 | -0.00508907 |
| EPHA4 | EPH receptor A4 | -0.00508763 |
| TMEM204 | transmembrane protein 204 | -0.00508109 |
| MFAP2 | microfibrillar-associated protein 2 | -0.00507486 |
| SLN | sarcolipin | -0.00506931 |
| RIOX2 | ribosomal oxygenase 2 | -0.00506354 |
| FBL | fibrillarin | -0.0050411 |
| DNM1L | dynamin 1-like | -0.00503001 |
| TAC1 | tachykinin, precursor 1 | -0.00502635 |
| MX2 | MX dynamin-like GTPase 2 | -0.00501288 |
| IDE | insulin-degrading enzyme | -0.00500983 |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) | -0.00500899 |
| BRD4 | bromodomain containing 4 | -0.00500127 |
| HOXC6 | homeobox C6 | -0.0049992 |
| QTRT1 | queuine tRNA-ribosyltransferase 1 | -0.0049926 |
| PTH2R | parathyroid hormone 2 receptor | -0.00499241 |
| CDK2AP1 | cyclin-dependent kinase 2 associated protein 1 | -0.00498982 |
| CDSN | corneodesmosin | -0.00498901 |
| APOBEC3A | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A | -0.00498335 |
| LAMA4 | laminin, alpha 4 | -0.00497506 |
| CHEK2 | checkpoint kinase 2 | -0.00497191 |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like | -0.0049674 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0049553 |
| DSG3 | desmoglein 3 | -0.00495222 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.00495186 |
| LCE2B | late cornified envelope 2B | -0.00493303 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.0049263 |
| GPNMB | glycoprotein (transmembrane) nmb | -0.00489763 |
| NPL | N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) | -0.00488665 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | -0.00488457 |
| C1QB | complement component 1, q subcomponent, B chain | -0.00487505 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.00487028 |
| AIM2 | absent in melanoma 2 | -0.00486968 |
| LOR | loricrin | -0.00486098 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.00485905 |
| HMOX1 | heme oxygenase 1 | -0.00485693 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -0.00485661 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | -0.00483879 |
| TLR2 | toll-like receptor 2 | -0.00483023 |
| LMNB1 | lamin B1 | -0.0048287 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | -0.00482488 |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | -0.0048242 |
| PSAT1 | phosphoserine aminotransferase 1 | -0.00479827 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.00479731 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | -0.00479278 |
| BCL2A1 | BCL2-related protein A1 | -0.00478326 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.00478243 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | -0.00477573 |
| TTK | TTK protein kinase | -0.00476634 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.00475936 |
| PRSS21 | protease, serine, 21 (testisin) | -0.00475561 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.00475533 |
| SNAI2 | snail family zinc finger 2 | -0.00475487 |
| ZNF124 | zinc finger protein 124 | -0.00475248 |
| RHOH | ras homolog family member H | -0.00472181 |
| TLR4 | toll-like receptor 4 | -0.00470526 |
| RPL36 | ribosomal protein L36 | -0.00469667 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase | -0.00469282 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | -0.00467104 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.00466409 |
| CREG1 | cellular repressor of E1A-stimulated genes 1 | -0.00464941 |
| NREP | neuronal regeneration related protein | -0.00464679 |
| ITGA8 | integrin, alpha 8 | -0.00464461 |
| GCH1 | GTP cyclohydrolase 1 | -0.00463052 |
| MMP8 | matrix metallopeptidase 8 | -0.00462877 |
| CYP20A1 | cytochrome P450, family 20, subfamily A, polypeptide 1 | -0.00462037 |
| PRRX1 | paired related homeobox 1 | -0.00461374 |
| XBP1 | X-box binding protein 1 | -0.00460357 |
| GIMAP5 | GTPase, IMAP family member 5 | -0.0045994 |
| DCLK1 | doublecortin-like kinase 1 | -0.00459935 |
| ZNF160 | zinc finger protein 160 | -0.00459051 |
| CLEC2B | C-type lectin domain family 2, member B | -0.00458992 |
| AUTS2 | autism susceptibility candidate 2 | -0.0045884 |
| IL18 | interleukin 18 | -0.00458749 |
| IFI30 | interferon, gamma-inducible protein 30 | -0.00458662 |
| LSP1 | lymphocyte-specific protein 1 | -0.00458549 |
| GLUL | glutamate-ammonia ligase | -0.0045813 |
| THBS2 | thrombospondin 2 | -0.00457817 |
| FBXO11 | F-box protein 11 | -0.00457806 |
| MED21 | mediator complex subunit 21 | -0.00456508 |
| EDN3 | endothelin 3 | -0.00455834 |
| POSTN | periostin, osteoblast specific factor | -0.00455158 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | -0.00455001 |
| CLEC7A | C-type lectin domain family 7, member A | -0.0045438 |
| YBX3 | Y box binding protein 3 | -0.00453901 |
| CD53 | CD53 molecule | -0.00453584 |
| ACTC1 | actin, alpha, cardiac muscle 1 | -0.0045246 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | -0.00452186 |
| ATF4 | activating transcription factor 4 | -0.00452139 |
| DDX39A | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A | -0.00451774 |
| ANGPTL4 | angiopoietin-like 4 | -0.0045133 |
| C5AR1 | complement component 5a receptor 1 | -0.00450602 |
| NUP50 | nucleoporin 50kDa | -0.00449744 |
| CD164 | CD164 molecule, sialomucin | -0.00449201 |
| LYPD3 | LY6/PLAUR domain containing 3 | -0.00448847 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.00448562 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | -0.00448501 |
| PRR11 | proline rich 11 | -0.00448293 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | -0.00448199 |
| CROCCP2 | ciliary rootlet coiled-coil, rootletin pseudogene 2 | -0.00448144 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.00447187 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | -0.00447171 |
| DPYD | dihydropyrimidine dehydrogenase | -0.00446811 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.00446742 |
| MTREX | Mtr4 exosome RNA helicase | -0.00445453 |
| USP15 | ubiquitin specific peptidase 15 | -0.00444679 |
| RRP15 | ribosomal RNA processing 15 homolog (S. cerevisiae) | -0.00443473 |
