BSPRY Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description B-box and SPRY domain containing| (NCBI Entrez Gene Database, 54836)
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Genes

341 genes differentially expressed following the BSPRY gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
GPR55 G protein-coupled receptor 55 2.82643
HES4 hes family bHLH transcription factor 4 2.82643
GJB1 gap junction protein, beta 1, 32kDa 2.82643
PDE7B phosphodiesterase 7B 2.82643
APOA2 apolipoprotein A-II 2.82643
OLIG1 oligodendrocyte transcription factor 1 2.82643
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 2.82643
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 2.82643
SCNN1G sodium channel, non voltage gated 1 gamma subunit 2.82643
SLC30A2 solute carrier family 30 (zinc transporter), member 2 2.82643
CA1 carbonic anhydrase I 2.82643
TMEM151B transmembrane protein 151B 2.82643
MBLAC1 metallo-beta-lactamase domain containing 1 2.82643
SLC26A9 solute carrier family 26 (anion exchanger), member 9 2.82643
SERPINA11 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11 2.82643
IGFL3 IGF-like family member 3 2.82643
PLIN1 perilipin 1 2.82643
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy 2.82643
PGAM2 phosphoglycerate mutase 2 (muscle) 2.82643
TRIM15 tripartite motif containing 15 2.82643
ZEB2 zinc finger E-box binding homeobox 2 2.82643
PDIA2 protein disulfide isomerase family A, member 2 2.82643
PDYN prodynorphin 2.82643
SLC39A5 solute carrier family 39 (zinc transporter), member 5 2.82643
F7 coagulation factor VII (serum prothrombin conversion accelerator) 2.82643
LRRC10B leucine rich repeat containing 10B 2.82643
TMC2 transmembrane channel-like 2 2.82643
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide 2.82643
THSD1 thrombospondin, type I, domain containing 1 2.82643
RPEL1 ribulose-5-phosphate-3-epimerase-like 1 2.82643
AIPL1 aryl hydrocarbon receptor interacting protein-like 1 2.82643
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 2.82643
CFAP53 cilia and flagella associated protein 53 2.82643
SLC10A4 solute carrier family 10, member 4 2.82643
SLC10A6 solute carrier family 10 (sodium/bile acid cotransporter), member 6 2.82643
ERAP2 endoplasmic reticulum aminopeptidase 2 2.82643
BMP5 bone morphogenetic protein 5 2.82643
MPO myeloperoxidase 2.82643
LCN12 lipocalin 12 2.82643
SPP2 secreted phosphoprotein 2, 24kDa 2.82643
OR52B6 olfactory receptor, family 52, subfamily B, member 6 2.82643
SMIM9 small integral membrane protein 9 2.82643
CLEC5A C-type lectin domain family 5, member A 2.82643
KIF2B kinesin family member 2B 2.82643
GPR101 G protein-coupled receptor 101 2.82643
LBX2 ladybird homeobox 2 2.82643
B3GNT8 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8 2.82643
SLC37A2 solute carrier family 37 (glucose-6-phosphate transporter), member 2 2.82643
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 2.82643
CHRND cholinergic receptor, nicotinic, delta (muscle) 2.82643
COXFA4L2 cytochrome c oxidase hypoxia associated subunit FA4L2 2.82643
SMIM40 small integral membrane protein 40 2.82643
HTD2 hydroxyacyl-thioester dehydratase type 2 2.82643
PHF24 PHD finger protein 24 2.82643
LTB4R2 leukotriene B4 receptor 2 2.82643
AANAT aralkylamine N-acetyltransferase 2.82643
TRPC7 transient receptor potential cation channel, subfamily C, member 7 2.82643
FMO3 flavin containing monooxygenase 3 2.82643
PKD2L1 polycystic kidney disease 2-like 1 2.82643
TMPRSS6 transmembrane protease, serine 6 2.82643
ASB9 ankyrin repeat and SOCS box containing 9 2.82643
CAVIN4 caveolae associated protein 4 2.82643
MPIG6B megakaryocyte and platelet inhibitory receptor G6b 2.82643
CIMIP7 ciliary microtubule inner protein 7 2.82643
EXOC1L exocyst complex component 1 like 2.82643
C17ORF113 chromosome 17 open reading frame 113 2.82643
LOC122526780 uncharacterized LOC122526780 2.82643
ZNF593OS ZNF593 opposite strand 2.82643
GNG5B G protein subunit gamma 5B 2.82643
H4C12 H4 clustered histone 12 2.82643
TEX55 testis expressed 55 2.82643
CFAP206 cilia and flagella associated protein 206 2.82643
SPDYE9 speedy/RINGO cell cycle regulator family member E9 2.82643
TSPAN1 tetraspanin 1 2.82643
TUBA4B tubulin, alpha 4b 2.82643
HNF1A HNF1 homeobox A 2.82643
RAET1E retinoic acid early transcript 1E 2.82643
SYCP2 synaptonemal complex protein 2 2.82643
PDILT protein disulfide isomerase-like, testis expressed 2.82643
MS4A6E membrane-spanning 4-domains, subfamily A, member 6E 2.82643
SRL sarcalumenin 2.82643
GPR75 G protein-coupled receptor 75 2.82643
SIX3 SIX homeobox 3 2.82643
HMGCLL1 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1 2.82643
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 2.82643
UCN urocortin 2.82643
RAET1G retinoic acid early transcript 1G 2.82643
FAM3D family with sequence similarity 3, member D 2.82643
OR13H1 olfactory receptor, family 13, subfamily H, member 1 2.82643
ALG10B ALG10B, alpha-1,2-glucosyltransferase 2.82643
GTSF1 gametocyte specific factor 1 2.82643
UTS2 urotensin 2 2.82643
C1QL2 complement component 1, q subcomponent-like 2 2.82643
OVOL3 ovo-like zinc finger 3 2.82643
HPR haptoglobin-related protein 2.82643
ZSWIM2 zinc finger, SWIM-type containing 2 2.82643
IRF8 interferon regulatory factor 8 2.82643
IZUMO1 izumo sperm-egg fusion 1 2.82643
USP29 ubiquitin specific peptidase 29 2.82643
ISLR immunoglobulin superfamily containing leucine-rich repeat 2.82643
OR9Q1 olfactory receptor, family 9, subfamily Q, member 1 2.82643
PCDHGB4 protocadherin gamma subfamily B, 4 2.82643
NACAD NAC alpha domain containing 2.82643
CRHBP corticotropin releasing hormone binding protein 2.82643
ZSCAN4 zinc finger and SCAN domain containing 4 2.82643
RBMXL3 RNA binding motif protein, X-linked-like 3 2.82643
SLC13A1 solute carrier family 13 (sodium/sulfate symporter), member 1 2.82643
THTPA thiamine triphosphatase 2.82643
KRT17 keratin 17, type I 2.82643
PRSS38 protease, serine, 38 2.82643
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 2.82643
TMPPE transmembrane protein with metallophosphoesterase domain 2.82643
MAPK11 mitogen-activated protein kinase 11 2.82643
OR1B1 olfactory receptor, family 1, subfamily B, member 1 (gene/pseudogene) 2.82643
ANKRD62 ankyrin repeat domain 62 2.82643
A3GALT2 alpha 1,3-galactosyltransferase 2 2.82643
PSG8 pregnancy specific beta-1-glycoprotein 8 2.82643
PENK proenkephalin 2.82643
TH tyrosine hydroxylase 2.82643
NANOGNB NANOG neighbor homeobox 2.82643
DIAPH3 diaphanous-related formin 3 2.82643
CCDC27 coiled-coil domain containing 27 2.82643
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 2.82643
SHROOM2 shroom family member 2 2.82643
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 2.82643
EVPLL envoplakin-like 2.82643
VWA3A von Willebrand factor A domain containing 3A 2.82643
IL1A interleukin 1, alpha 2.82643
TRIM55 tripartite motif containing 55 2.82643
HUS1B HUS1 checkpoint homolog b (S. pombe) 2.82643
LRRC15 leucine rich repeat containing 15 2.82643
GLOD5 glyoxalase domain containing 5 2.82643
TEX12 testis expressed 12 2.82643
GOLGA6C golgin A6 family, member C 2.82643
FBXO47 F-box protein 47 2.82643
TDRD10 tudor domain containing 10 2.82643
FBXO40 F-box protein 40 2.82643
CPA2 carboxypeptidase A2 (pancreatic) 2.82643
LOXHD1 lipoxygenase homology domains 1 2.82643
PPP1R3G protein phosphatase 1, regulatory subunit 3G 2.82643
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 2.82643
IL33 interleukin 33 2.82643
FRMPD2 FERM and PDZ domain containing 2 2.82643
TMEM156 transmembrane protein 156 2.82643
PTPN7 protein tyrosine phosphatase, non-receptor type 7 2.82643
GOLGA8R golgin A8 family, member R 2.82643
LRRC31 leucine rich repeat containing 31 2.82643
LRRC38 leucine rich repeat containing 38 2.82643
ADTRP androgen-dependent TFPI-regulating protein 2.82643
VWC2L von Willebrand factor C domain containing protein 2-like 2.82643
PODN podocan 2.82643
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 2.82643
NRSN1 neurensin 1 2.82643
HIGD1C HIG1 hypoxia inducible domain family, member 1C 2.82643
PCDH12 protocadherin 12 2.82643
DCST1 DC-STAMP domain containing 1 2.82643
NRGN neurogranin (protein kinase C substrate, RC3) 2.82643
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 2.82643
GRAP2 GRB2-related adaptor protein 2 2.82643
ROM1 retinal outer segment membrane protein 1 2.82643
ADAM12 ADAM metallopeptidase domain 12 2.82643
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 2.82643
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4 2.82643
CXORF58 chromosome X open reading frame 58 2.82643
CCDC70 coiled-coil domain containing 70 2.82643
LAMP5 lysosomal-associated membrane protein family, member 5 2.82643
ACKR2 atypical chemokine receptor 2 2.82643
PLGLB1 plasminogen-like B1 2.82643
NMBR neuromedin B receptor 2.82643
RTN4RL1 reticulon 4 receptor-like 1 2.82643
TET2 tet methylcytosine dioxygenase 2 2.78275
DUSP2 dual specificity phosphatase 2 2.78275
GNG7 guanine nucleotide binding protein (G protein), gamma 7 2.77315
CEP164 centrosomal protein 164kDa 2.73584
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 2.72608
CD38 CD38 molecule 2.72608
MMP20 matrix metallopeptidase 20 2.72608
VCX variable charge, X-linked 2.72608
TBCK TBC1 domain containing kinase 2.72608
CENPC centromere protein C 2.72149
PTBP3 polypyrimidine tract binding protein 3 2.67489
SLC41A1 solute carrier family 41 (magnesium transporter), member 1 2.56517
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 2.55762
HCRTR2 hypocretin (orexin) receptor 2 2.53541
RIBC1 RIB43A domain with coiled-coils 1 2.53541
SHISA3 shisa family member 3 2.53541
ZFPM2 zinc finger protein, FOG family member 2 2.53358
MAX MYC associated factor X 2.47384
UNC13B unc-13 homolog B (C. elegans) 2.44959
MAPK14 mitogen-activated protein kinase 14 2.44621
CHST9 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9 2.44248
POLB polymerase (DNA directed), beta 2.43087
MAP3K8 mitogen-activated protein kinase kinase kinase 8 2.41859
GOSR1 golgi SNAP receptor complex member 1 2.41859
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa 2.41314
DKC1 dyskeratosis congenita 1, dyskerin 2.40386
GLIPR1 GLI pathogenesis-related 1 2.38855
F2RL1 coagulation factor II (thrombin) receptor-like 1 2.38636
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11 2.36123
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa 2.30568
LAD1 ladinin 1 2.28921
ZNF749 zinc finger protein 749 2.27911
IFFO2 intermediate filament family orphan 2 2.2601
PPP4R3B protein phosphatase 4 regulatory subunit 3B 2.25955
C5ORF63 chromosome 5 open reading frame 63 2.24228
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4 2.23676
PDE5A phosphodiesterase 5A, cGMP-specific 2.22725
SLC30A5 solute carrier family 30 (zinc transporter), member 5 2.20798
AGAP5 ArfGAP with GTPase domain, ankyrin repeat and PH domain 5 2.20397
ZNF711 zinc finger protein 711 2.20397
MYBPC2 myosin binding protein C, fast type 2.20397
ZNF813 zinc finger protein 813 2.20397
TMX4 thioredoxin-related transmembrane protein 4 2.19085
KSR1 kinase suppressor of ras 1 2.18421
ACOT2 acyl-CoA thioesterase 2 2.15636
SELENOW selenoprotein W 2.15437
IAH1 isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae) 2.14928
NBPF14 neuroblastoma breakpoint family, member 14 2.14064
TRERF1 transcriptional regulating factor 1 2.13674
CROT carnitine O-octanoyltransferase 2.12781
FASTKD2 FAST kinase domains 2 2.12441
SNTG2 syntrophin, gamma 2 2.11278
MCM10 minichromosome maintenance complex component 10 2.10585
ZNF442 zinc finger protein 442 2.06558
KATNBL1 katanin p80 subunit B-like 1 2.05909
VAMP7 vesicle-associated membrane protein 7 2.05805
BCL7C B-cell CLL/lymphoma 7C 2.05805
AKR1C3 aldo-keto reductase family 1, member C3 2.04603
ZNF823 zinc finger protein 823 2.04407
ABHD12 abhydrolase domain containing 12 2.04402
FBXL15 F-box and leucine-rich repeat protein 15 2.04073
WDR12 WD repeat domain 12 2.02673
STX7 syntaxin 7 2.02409
SLC61A1 solute carrier family 61 member 1 2.02337
UROS uroporphyrinogen III synthase 2.01639
ASNSD1 asparagine synthetase domain containing 1 2.00312
MFSD2A major facilitator superfamily domain containing 2A 2.00196

decreased expression

Symbol Name Standardized Value
TMEM88 transmembrane protein 88 -2.82643
RFPL3 ret finger protein-like 3 -2.82643
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion -2.82643
TRIM77 tripartite motif containing 77 -2.82643
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13 -2.82643
SFXN3 sideroflexin 3 -2.82643
ADAM33 ADAM metallopeptidase domain 33 -2.82643
FIGNL2 fidgetin-like 2 -2.82643
SMAD7 SMAD family member 7 -2.82643
TRPV2 transient receptor potential cation channel, subfamily V, member 2 -2.82643
ECM1 extracellular matrix protein 1 -2.82643
PITX3 paired-like homeodomain 3 -2.82643
FAM161B family with sequence similarity 161, member B -2.82643
TMEM121 transmembrane protein 121 -2.82643
TGM2 transglutaminase 2 -2.82643
FRMPD4 FERM and PDZ domain containing 4 -2.82643
LEP leptin -2.82643
NWD1 NACHT and WD repeat domain containing 1 -2.82643
SLC30A10 solute carrier family 30, member 10 -2.82643
ADIRF adipogenesis regulatory factor -2.82643
CXORF65 chromosome X open reading frame 65 -2.82643
DCAF4L1 DDB1 and CUL4 associated factor 4-like 1 -2.82643
C1ORF162 chromosome 1 open reading frame 162 -2.82643
BLNK B-cell linker -2.82643
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase) -2.82643
C2ORF72 chromosome 2 open reading frame 72 -2.82643
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 -2.82643
NFIX nuclear factor I/X (CCAAT-binding transcription factor) -2.82643
GPAT3 glycerol-3-phosphate acyltransferase 3 -2.82643
TAPBPL TAP binding protein-like -2.82643
PCDHB10 protocadherin beta 10 -2.82643
SBK2 SH3 domain binding kinase family, member 2 -2.82643
MAT1A methionine adenosyltransferase I, alpha -2.82643
CAPN11 calpain 11 -2.82643
CMKLR1 chemerin chemokine-like receptor 1 -2.82643
KLK4 kallikrein-related peptidase 4 -2.82643
IRF2-DT IRF2 divergent transcript -2.82643
TSGA13 testis specific, 13 -2.82643
IGFL4 IGF-like family member 4 -2.82643
NPR1 natriuretic peptide receptor 1 -2.80485
UFSP2 UFM1-specific peptidase 2 -2.78777
PYY peptide YY -2.77407
CHN2 chimerin 2 -2.75172
EPB41L4B erythrocyte membrane protein band 4.1 like 4B -2.73584
ADORA1 adenosine A1 receptor -2.72608
CPM carboxypeptidase M -2.72608
CAPN6 calpain 6 -2.72608
CLK1 CDC-like kinase 1 -2.72149
TMEM131L transmembrane 131 like -2.6744
SPIN4 spindlin family, member 4 -2.47754
TMEM62 transmembrane protein 62 -2.43853
SMAP2 small ArfGAP2 -2.43853
LIPI lipase, member I -2.43087
XKR8 XK, Kell blood group complex subunit-related family, member 8 -2.42265
RHNO1 RAD9-HUS1-RAD1 interacting nuclear orphan 1 -2.41125
NRG2 neuregulin 2 -2.36387
B3GALT5 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 -2.34169
MAP1LC3B2 microtubule-associated protein 1 light chain 3 beta 2 -2.3399
ACTN3 actinin, alpha 3 (gene/pseudogene) -2.30134
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) -2.29193
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 -2.28862
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -2.28862
CEMIP2 cell migration inducing hyaluronidase 2 -2.27195
COPS8 COP9 signalosome subunit 8 -2.25955
MED13 mediator complex subunit 13 -2.25498
PHF19 PHD finger protein 19 -2.24345
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 -2.23676
ARL14EP ADP-ribosylation factor-like 14 effector protein -2.22343
HMGN1 high mobility group nucleosome binding domain 1 -2.21237
TRPT1 tRNA phosphotransferase 1 -2.20397
IPCEF1 interaction protein for cytohesin exchange factors 1 -2.20397
EFNA3 ephrin-A3 -2.20397
CDK2AP1 cyclin-dependent kinase 2 associated protein 1 -2.20397
STX1B syntaxin 1B -2.20397
PLAU plasminogen activator, urokinase -2.20127
PCNP PEST proteolytic signal containing nuclear protein -2.19987
GDAP2 ganglioside induced differentiation associated protein 2 -2.19051
CDX4 caudal type homeobox 4 -2.18873
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha -2.17826
NBPF10 neuroblastoma breakpoint family, member 10 -2.15644
BMP1 bone morphogenetic protein 1 -2.15644
ELAVL2 ELAV like neuron-specific RNA binding protein 2 -2.15636
COG2 component of oligomeric golgi complex 2 -2.15636
SMIM24 small integral membrane protein 24 -2.15437
PPCS phosphopantothenoylcysteine synthetase -2.15437
RND1 Rho family GTPase 1 -2.15437
LCOR ligand dependent nuclear receptor corepressor -2.1524
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 -2.1524
TP73 tumor protein p73 -2.1524
TNS2 tensin 2 -2.14806
EBF2 early B-cell factor 2 -2.14806
RSRP1 arginine/serine-rich protein 1 -2.12766
ANKUB1 ankyrin repeat and ubiquitin domain containing 1 -2.09405
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -2.05757
H4C5 H4 clustered histone 5 -2.04276
PMP22 peripheral myelin protein 22 -2.04276
TMEM221 transmembrane protein 221 -2.04276
MINPP1 multiple inositol-polyphosphate phosphatase 1 -2.03983
SELENOO selenoprotein O -2.03317
MAML1 mastermind-like 1 (Drosophila) -2.02337
ZNF345 zinc finger protein 345 -2.02322
CMTR2 cap methyltransferase 2 -2.01582
MARCHF8 membrane associated ring-CH-type finger 8 -2.01003
C2CD2 C2 calcium-dependent domain containing 2 -2.00665