BT474 Gene Set

Dataset Achilles Cell Line Gene Essentiality Profiles
Category disease or phenotype associations
Type cell line
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Genes

565 gene knockdowns changing fitness of BT474 relative to other cell lines from the Achilles Cell Line Gene Essentiality Profiles dataset.

increased fitness

Symbol Name Standardized Value
SLC39A1 solute carrier family 39 (zinc transporter), member 1 3.19303
TRIP10 thyroid hormone receptor interactor 10 3.18864
EFCAB1 EF-hand calcium binding domain 1 3.18682
DLK2 delta-like 2 homolog (Drosophila) 3.16897
HIBADH 3-hydroxyisobutyrate dehydrogenase 2.94002
RANBP9 RAN binding protein 9 2.83643
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 2.65303
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like 2.53174
CNTF ciliary neurotrophic factor 2.49812
KIF20A kinesin family member 20A 2.48657
PZP pregnancy-zone protein 2.48544
OCM oncomodulin 2.43455
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 2.43167
FPGS folylpolyglutamate synthase 2.26651
BCL9L B-cell CLL/lymphoma 9-like 2.26162
ILF2 interleukin enhancer binding factor 2 2.26138
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4 2.25661
DNTT DNA nucleotidylexotransferase 2.2214
SMG6 SMG6 nonsense mediated mRNA decay factor 2.16612
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 2.14965
PRCC papillary renal cell carcinoma (translocation-associated) 2.14503
VCP valosin containing protein 2.11422
PTENP1 phosphatase and tensin homolog pseudogene 1 (functional) 2.08441
RAB21 RAB21, member RAS oncogene family 2.073
LMO4 LIM domain only 4 2.06934
FBLN1 fibulin 1 2.05637
RLF rearranged L-myc fusion 2.05585
NGF nerve growth factor (beta polypeptide) 2.02145
FURIN furin (paired basic amino acid cleaving enzyme) 2.02047
PAX9 paired box 9 2.0118
TSSK3 testis-specific serine kinase 3 2.00851
BIRC8 baculoviral IAP repeat containing 8 1.99585
U2SURP U2 snRNP-associated SURP domain containing 1.98487
RNASE8 ribonuclease, RNase A family, 8 1.9773
OR8S1 olfactory receptor, family 8, subfamily S, member 1 1.97483
TLX1 T-cell leukemia homeobox 1 1.95115
OPN5 opsin 5 1.93859
ELMO2 engulfment and cell motility 2 1.92525
ETV7 ets variant 7 1.90691
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 1.88888
PTEN phosphatase and tensin homolog 1.87282
RAP1B RAP1B, member of RAS oncogene family 1.86421
INPP5K inositol polyphosphate-5-phosphatase K 1.84123
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 1.83954
MT3 metallothionein 3 1.82825
ADAM17 ADAM metallopeptidase domain 17 1.8215
CDKL3 cyclin-dependent kinase-like 3 1.81619
ESRRA estrogen-related receptor alpha 1.81508
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3 1.80511
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed 1.79578
HLX H2.0-like homeobox 1.78786
FUBP3 far upstream element (FUSE) binding protein 3 1.78571
EPS8 epidermal growth factor receptor pathway substrate 8 1.78106
GFOD2 glucose-fructose oxidoreductase domain containing 2 1.77601
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5 1.77039
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 1.76255
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 1.75589
SP7 Sp7 transcription factor 1.75055
CRMP1 collapsin response mediator protein 1 1.74346
ANAPC2 anaphase promoting complex subunit 2 1.7393
MLKL mixed lineage kinase domain-like 1.73673
ARID1B AT rich interactive domain 1B (SWI1-like) 1.72417
IKZF5 IKAROS family zinc finger 5 (Pegasus) 1.70632
EPAS1 endothelial PAS domain protein 1 1.7054
STX1B syntaxin 1B 1.7048
ATF7 activating transcription factor 7 1.70394
PADI3 peptidyl arginine deiminase, type III 1.70204
AMY2B amylase, alpha 2B (pancreatic) 1.68378
PRKD1 protein kinase D1 1.67927
ZFP91-CNTF ZFP91-CNTF readthrough (NMD candidate) 1.67572
IRF2BP2 interferon regulatory factor 2 binding protein 2 1.67122
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 1.64738
CETP cholesteryl ester transfer protein, plasma 1.64101
RGS11 regulator of G-protein signaling 11 1.63817
ZNF621 zinc finger protein 621 1.63075
HSDL2 hydroxysteroid dehydrogenase like 2 1.62541
LILRA3 leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3 1.6241
SLC35E4 solute carrier family 35, member E4 1.62329
IKZF2 IKAROS family zinc finger 2 (Helios) 1.61614
OSTM1 osteopetrosis associated transmembrane protein 1 1.61313
SPRED2 sprouty-related, EVH1 domain containing 2 1.61307
RAB35 RAB35, member RAS oncogene family 1.6046
ZFP36L1 ZFP36 ring finger protein-like 1 1.60022
RABEP1 rabaptin, RAB GTPase binding effector protein 1 1.59563
CDX4 caudal type homeobox 4 1.58691
ZKSCAN4 zinc finger with KRAB and SCAN domains 4 1.58685
TCEA1 transcription elongation factor A (SII), 1 1.58532
PLXNC1 plexin C1 1.58421
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene) 1.58159
RARS2 arginyl-tRNA synthetase 2, mitochondrial 1.57994
MCTS1 malignant T cell amplified sequence 1 1.57361
SLC26A11 solute carrier family 26 (anion exchanger), member 11 1.56605
TPK1 thiamin pyrophosphokinase 1 1.56156
SCNN1G sodium channel, non voltage gated 1 gamma subunit 1.55035
EGLN2 egl-9 family hypoxia-inducible factor 2 1.53712
PDCD6IP programmed cell death 6 interacting protein 1.53122
METTL4 methyltransferase like 4 1.52929
FBXO9 F-box protein 9 1.52905
FOSL2 FOS-like antigen 2 1.52833
CDK18 cyclin-dependent kinase 18 1.51782
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 1.51554
SNRPE small nuclear ribonucleoprotein polypeptide E 1.51242
NT5M 5',3'-nucleotidase, mitochondrial 1.50774
TRAF1 TNF receptor-associated factor 1 1.50733
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) 1.50686
AMY2A amylase, alpha 2A (pancreatic) 1.50671
VAMP7 vesicle-associated membrane protein 7 1.49355
KCTD3 potassium channel tetramerization domain containing 3 1.48161
SFXN2 sideroflexin 2 1.46815
MATN3 matrilin 3 1.45996
EBAG9 estrogen receptor binding site associated, antigen, 9 1.45933
MAPK9 mitogen-activated protein kinase 9 1.4573
DERA deoxyribose-phosphate aldolase (putative) 1.45181
GPR135 G protein-coupled receptor 135 1.43213
OR56B1 olfactory receptor, family 56, subfamily B, member 1 1.43179
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 1.4245
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast) 1.42001
WEE1 WEE1 G2 checkpoint kinase 1.41692
RGS17 regulator of G-protein signaling 17 1.41625
PDIK1L PDLIM1 interacting kinase 1 like 1.41365
SLC30A8 solute carrier family 30 (zinc transporter), member 8 1.41187
EYS eyes shut homolog (Drosophila) 1.40916
SLC7A10 solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10 1.39913
SCN2A sodium channel, voltage gated, type II alpha subunit 1.3965
IL17RC interleukin 17 receptor C 1.39297
NES nestin 1.39182
GATA6 GATA binding protein 6 1.38902
CLCA4 chloride channel accessory 4 1.38419
FMNL1 formin-like 1 1.38078
ALG1 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase 1.37686
MAP2K6 mitogen-activated protein kinase kinase 6 1.37575
HACL1 2-hydroxyacyl-CoA lyase 1 1.37489
APOO apolipoprotein O 1.37374
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B 1.37314
RAB5B RAB5B, member RAS oncogene family 1.35852
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 1.35545
ZNF793 zinc finger protein 793 1.35415
RASL10B RAS-like, family 10, member B 1.35318
F2RL1 coagulation factor II (thrombin) receptor-like 1 1.34382
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 1.3416
CUL9 cullin 9 1.34047
TRPM5 transient receptor potential cation channel, subfamily M, member 5 1.33837
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9) 1.33601
FUS FUS RNA binding protein 1.33442
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 1.33101
NPTXR neuronal pentraxin receptor 1.3292
SLC31A1 solute carrier family 31 (copper transporter), member 1 1.32774
EFNB2 ephrin-B2 1.3165
MFN1 mitofusin 1 1.30394
C18ORF8 chromosome 18 open reading frame 8 1.29817
ZNF775 zinc finger protein 775 1.2978
SLC35A4 solute carrier family 35, member A4 1.29433
FCRLA Fc receptor-like A 1.29382
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 1.28514
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase 1.28264
CREG1 cellular repressor of E1A-stimulated genes 1 1.27851
ZNF766 zinc finger protein 766 1.27841
MEF2A myocyte enhancer factor 2A 1.27501
SLCO4A1 solute carrier organic anion transporter family, member 4A1 1.27225
WIF1 WNT inhibitory factor 1 1.27038
MGAT4C MGAT4 family, member C 1.26969
FN3K fructosamine 3 kinase 1.26922
RGS1 regulator of G-protein signaling 1 1.26275
SLC10A3 solute carrier family 10, member 3 1.25882
BIRC6 baculoviral IAP repeat containing 6 1.24532
PDE11A phosphodiesterase 11A 1.24397
RNF20 ring finger protein 20, E3 ubiquitin protein ligase 1.23428
STS steroid sulfatase (microsomal), isozyme S 1.23425
CTDNEP1 CTD nuclear envelope phosphatase 1 1.23409
PARP6 poly (ADP-ribose) polymerase family, member 6 1.23382
HIST1H2BB histone cluster 1, H2bb 1.23252
MBOAT7 membrane bound O-acyltransferase domain containing 7 1.22983
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha 1.22686
CSE1L CSE1 chromosome segregation 1-like (yeast) 1.22684
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 1.22288
TSC1 tuberous sclerosis 1 1.2202
PEBP1 phosphatidylethanolamine binding protein 1 1.2195
CD300C CD300c molecule 1.21888
SLC30A7 solute carrier family 30 (zinc transporter), member 7 1.20936
MYL4 myosin, light chain 4, alkali; atrial, embryonic 1.20914
PCSK4 proprotein convertase subtilisin/kexin type 4 1.19637
WNT4 wingless-type MMTV integration site family, member 4 1.19257
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 1.19163
ZNF628 zinc finger protein 628 1.19071
EMD emerin 1.18794
FZD4 frizzled class receptor 4 1.18634
POLR3B polymerase (RNA) III (DNA directed) polypeptide B 1.18269
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) 1.17359
MAB21L2 mab-21-like 2 (C. elegans) 1.17248
HMSD histocompatibility (minor) serpin domain containing 1.16975
PRTN3 proteinase 3 1.16854
PHF1 PHD finger protein 1 1.16049
PVRL4 poliovirus receptor-related 4 1.16015
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 1.15863
AKAP8 A kinase (PRKA) anchor protein 8 1.15778
PPA1 pyrophosphatase (inorganic) 1 1.15513
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1 1.15273
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 1.14793
RNF183 ring finger protein 183 1.14405
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 1.14097
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5 1.1399
PRF1 perforin 1 (pore forming protein) 1.13872
SLC10A4 solute carrier family 10, member 4 1.137
RAB33A RAB33A, member RAS oncogene family 1.13694
LPP LIM domain containing preferred translocation partner in lipoma 1.12576
FOXR1 forkhead box R1 1.12574
HSD11B1L hydroxysteroid (11-beta) dehydrogenase 1-like 1.11636
VN1R1 vomeronasal 1 receptor 1 1.11262
SSX8 synovial sarcoma, X breakpoint 8 1.10622
F3 coagulation factor III (thromboplastin, tissue factor) 1.10555
TMPRSS11B transmembrane protease, serine 11B 1.10552
ACO1 aconitase 1, soluble 1.10496
LIN52 lin-52 DREAM MuvB core complex component 1.10494
UGT1A4 UDP glucuronosyltransferase 1 family, polypeptide A4 1.10169
RETSAT retinol saturase (all-trans-retinol 13,14-reductase) 1.09766
AGTR1 angiotensin II receptor, type 1 1.09741
PNPLA6 patatin-like phospholipase domain containing 6 1.09048
PCDHA4 protocadherin alpha 4 1.08508
LMNB1 lamin B1 1.08475
CETN3 centrin, EF-hand protein, 3 1.08344
KIF1B kinesin family member 1B 1.07935
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 1.07821
TUFT1 tuftelin 1 1.07564
SLCO2A1 solute carrier organic anion transporter family, member 2A1 1.07341
SSH3 slingshot protein phosphatase 3 1.06585
ADNP activity-dependent neuroprotector homeobox 1.06563
SLC15A4 solute carrier family 15 (oligopeptide transporter), member 4 1.06556
MICA MHC class I polypeptide-related sequence A 1.06473
SSX6 synovial sarcoma, X breakpoint 6 (pseudogene) 1.06243
ADGRE1 adhesion G protein-coupled receptor E1 1.05925
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 1.05249
CDC5L cell division cycle 5-like 1.05091
OPN4 opsin 4 1.0499
COBL cordon-bleu WH2 repeat protein 1.04941
CD1C CD1c molecule 1.04657
CPA4 carboxypeptidase A4 1.0459
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 1.04419
IFNGR1 interferon gamma receptor 1 1.04302
BAZ2B bromodomain adjacent to zinc finger domain, 2B 1.04055
ADGRG6 adhesion G protein-coupled receptor G6 1.04054
UBR1 ubiquitin protein ligase E3 component n-recognin 1 1.03992
TBL3 transducin (beta)-like 3 1.03969
HCAR2 hydroxycarboxylic acid receptor 2 1.03898
SLC25A18 solute carrier family 25 (glutamate carrier), member 18 1.03766
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 1.03672
HNRNPA1L2 heterogeneous nuclear ribonucleoprotein A1-like 2 1.03532
SOCS4 suppressor of cytokine signaling 4 1.03453
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) 1.03362
KRTAP5-2 keratin associated protein 5-2 1.03157
MOB3A MOB kinase activator 3A 1.03122
MOGAT1 monoacylglycerol O-acyltransferase 1 1.02695
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 1.02688
SCN1A sodium channel, voltage gated, type I alpha subunit 1.01014
ADAM29 ADAM metallopeptidase domain 29 1.00917
TASP1 taspase, threonine aspartase, 1 1.00767
OR52L1 olfactory receptor, family 52, subfamily L, member 1 1.00697
IRF2BP1 interferon regulatory factor 2 binding protein 1 1.00638
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3 1.00489
TBC1D25 TBC1 domain family, member 25 1.00333
RHAG Rh-associated glycoprotein 1.00247
LIG3 ligase III, DNA, ATP-dependent 1.00108

decreased fitness

Symbol Name Standardized Value
MMP25 matrix metallopeptidase 25 -3.57722
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) -3.5252
BGLAP bone gamma-carboxyglutamate (gla) protein -3.41747
PMF1-BGLAP PMF1-BGLAP readthrough -3.30089
DPRX divergent-paired related homeobox -3.18902
RAB23 RAB23, member RAS oncogene family -2.84351
SP1 Sp1 transcription factor -2.83411
IFNA16 interferon, alpha 16 -2.80733
GRSF1 G-rich RNA sequence binding factor 1 -2.79545
BEGAIN brain-enriched guanylate kinase-associated -2.70965
AKT1 v-akt murine thymoma viral oncogene homolog 1 -2.67742
TUBA3C tubulin, alpha 3c -2.58021
FYN FYN proto-oncogene, Src family tyrosine kinase -2.55707
ZNF345 zinc finger protein 345 -2.50785
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3 -2.50268
ZIK1 zinc finger protein interacting with K protein 1 -2.49982
ERBB3 erb-b2 receptor tyrosine kinase 3 -2.44524
TOP1 topoisomerase (DNA) I -2.4059
POLN polymerase (DNA directed) nu -2.40482
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) -2.36306
GTF2A1 general transcription factor IIA, 1, 19/37kDa -2.35491
GFPT2 glutamine-fructose-6-phosphate transaminase 2 -2.34593
CHD8 chromodomain helicase DNA binding protein 8 -2.31723
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa -2.29823
G3BP2 GTPase activating protein (SH3 domain) binding protein 2 -2.28566
TBX3 T-box 3 -2.25818
MAP3K12 mitogen-activated protein kinase kinase kinase 12 -2.24096
RHEB Ras homolog enriched in brain -2.23439
CIAO1 cytosolic iron-sulfur assembly component 1 -2.21237
PFN1 profilin 1 -2.20801
GTF2A2 general transcription factor IIA, 2, 12kDa -2.19335
SRRM2 serine/arginine repetitive matrix 2 -2.1155
NR1H4 nuclear receptor subfamily 1, group H, member 4 -2.11086
CAPN2 calpain 2, (m/II) large subunit -2.04574
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -2.03547
VARS valyl-tRNA synthetase -2.03416
GRHL2 grainyhead-like 2 (Drosophila) -2.02317
INTS4P2 integrator complex subunit 4 pseudogene 2 -2.0211
ADRA1B adrenoceptor alpha 1B -2.01392
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 -1.9776
CCND1 cyclin D1 -1.94119
INTS4 integrator complex subunit 4 -1.93682
ELL elongation factor RNA polymerase II -1.93493
EHMT1 euchromatic histone-lysine N-methyltransferase 1 -1.93472
RHOA ras homolog family member A -1.92956
INTS6 integrator complex subunit 6 -1.91964
SYT7 synaptotagmin VII -1.90958
ADCK1 aarF domain containing kinase 1 -1.90412
INTS4P1 integrator complex subunit 4 pseudogene 1 -1.89198
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa -1.89108
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) -1.89075
SLC30A9 solute carrier family 30 (zinc transporter), member 9 -1.88367
DPEP2 dipeptidase 2 -1.85524
C19ORF43 chromosome 19 open reading frame 43 -1.85183
NCBP1 nuclear cap binding protein subunit 1, 80kDa -1.84631
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa -1.84011
SRM spermidine synthase -1.83913
ZNF702P zinc finger protein 702, pseudogene -1.83577
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -1.83449
ACSM1 acyl-CoA synthetase medium-chain family member 1 -1.82423
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa -1.8172
BAAT bile acid CoA:amino acid N-acyltransferase -1.81663
LIMK2 LIM domain kinase 2 -1.8166
ZNF579 zinc finger protein 579 -1.76135
IP6K3 inositol hexakisphosphate kinase 3 -1.75843
PPP1R15B protein phosphatase 1, regulatory subunit 15B -1.74781
SGK1 serum/glucocorticoid regulated kinase 1 -1.74673
ALDH3B2 aldehyde dehydrogenase 3 family, member B2 -1.74201
CAPZB capping protein (actin filament) muscle Z-line, beta -1.73241
BRI3 brain protein I3 -1.72444
REXO2 RNA exonuclease 2 -1.72438
UBE2J1 ubiquitin-conjugating enzyme E2, J1 -1.716
MTOR mechanistic target of rapamycin (serine/threonine kinase) -1.70527
TK1 thymidine kinase 1, soluble -1.70301
SPDEF SAM pointed domain containing ETS transcription factor -1.68976
TEAD2 TEA domain family member 2 -1.68274
GTF3C3 general transcription factor IIIC, polypeptide 3, 102kDa -1.67918
RPGRIP1 retinitis pigmentosa GTPase regulator interacting protein 1 -1.67467
TUBB tubulin, beta class I -1.66765
PDHA2 pyruvate dehydrogenase (lipoamide) alpha 2 -1.65791
SET SET nuclear proto-oncogene -1.65427
SNAPIN SNAP-associated protein -1.64801
SEC62 SEC62 homolog (S. cerevisiae) -1.64454
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa -1.63981
LOC100508408 -1.63676
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) -1.62785
CDC37 cell division cycle 37 -1.6271
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha -1.623
ZNF556 zinc finger protein 556 -1.62112
CARS cysteinyl-tRNA synthetase -1.61505
CCL8 chemokine (C-C motif) ligand 8 -1.61491
ZFX zinc finger protein, X-linked -1.61074
BPTF bromodomain PHD finger transcription factor -1.60761
RING1 ring finger protein 1 -1.60033
YBX1 Y box binding protein 1 -1.59758
CCNE2 cyclin E2 -1.58897
XAB2 XPA binding protein 2 -1.57976
INSM2 insulinoma-associated 2 -1.57578
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 -1.57359
ZBTB45 zinc finger and BTB domain containing 45 -1.57007
TSPAN17 tetraspanin 17 -1.56826
PRDM10 PR domain containing 10 -1.56505
LAMP1 lysosomal-associated membrane protein 1 -1.56502
NUP98 nucleoporin 98kDa -1.54632
POR P450 (cytochrome) oxidoreductase -1.53993
PTDSS1 phosphatidylserine synthase 1 -1.53487
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 -1.53399
CDC34 cell division cycle 34 -1.52333
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11 -1.5222
WNK1 WNK lysine deficient protein kinase 1 -1.52007
SEC13 SEC13 homolog (S. cerevisiae) -1.51623
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha -1.51529
TBP TATA box binding protein -1.50439
RPS13 ribosomal protein S13 -1.49217
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa -1.48867
LRPPRC leucine-rich pentatricopeptide repeat containing -1.47461
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein -1.46454
SLC39A4 solute carrier family 39 (zinc transporter), member 4 -1.46071
RPSAP58 ribosomal protein SA pseudogene 58 -1.46039
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) -1.45555
DDR2 discoidin domain receptor tyrosine kinase 2 -1.45487
OR7C2 olfactory receptor, family 7, subfamily C, member 2 -1.45342
DLG5 discs, large homolog 5 (Drosophila) -1.45042
ZNF611 zinc finger protein 611 -1.44744
GPSM1 G-protein signaling modulator 1 -1.44665
SRSF7 serine/arginine-rich splicing factor 7 -1.43847
USP39 ubiquitin specific peptidase 39 -1.43569
ASRGL1 asparaginase like 1 -1.43087
TAS2R38 taste receptor, type 2, member 38 -1.42746
GALE UDP-galactose-4-epimerase -1.42127
KAT2A K(lysine) acetyltransferase 2A -1.41638
AHCY adenosylhomocysteinase -1.41361
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase -1.40858
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 -1.40528
TLE3 transducin-like enhancer of split 3 -1.4036
ZNF490 zinc finger protein 490 -1.39662
WDR54 WD repeat domain 54 -1.39404
SKAP1 src kinase associated phosphoprotein 1 -1.39389
OVOL1 ovo-like zinc finger 1 -1.38708
NEUROG2 neurogenin 2 -1.38675
DHX30 DEAH (Asp-Glu-Ala-His) box helicase 30 -1.38468
UBE2R2 ubiquitin-conjugating enzyme E2R 2 -1.38196
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 -1.37935
TSG101 tumor susceptibility 101 -1.37884
RREB1 ras responsive element binding protein 1 -1.37052
WDR33 WD repeat domain 33 -1.37009
TDRD9 tudor domain containing 9 -1.36898
AWAT2 acyl-CoA wax alcohol acyltransferase 2 -1.36855
PA2G4 proliferation-associated 2G4, 38kDa -1.36766
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 -1.36102
PSEN2 presenilin 2 -1.35745
NECAB2 N-terminal EF-hand calcium binding protein 2 -1.35588
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) -1.35332
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit -1.35095
C1ORF87 chromosome 1 open reading frame 87 -1.35059
ZNF860 zinc finger protein 860 -1.34979
FOXA1 forkhead box A1 -1.34792
CPSF2 cleavage and polyadenylation specific factor 2, 100kDa -1.34721
RUVBL2 RuvB-like AAA ATPase 2 -1.34411
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2 -1.34364
PCDHGA10 protocadherin gamma subfamily A, 10 -1.34316
EWSR1 EWS RNA-binding protein 1 -1.32894
RPS14 ribosomal protein S14 -1.32237
RPSA ribosomal protein SA -1.32185
CNGB3 cyclic nucleotide gated channel beta 3 -1.32129
ZNF57 zinc finger protein 57 -1.32121
TGFBR3 transforming growth factor, beta receptor III -1.3208
ERBB2IP erbb2 interacting protein -1.32072
CPB1 carboxypeptidase B1 (tissue) -1.3202
HMGXB4 HMG box domain containing 4 -1.31473
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -1.31378
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 -1.31271
EIF3E eukaryotic translation initiation factor 3, subunit E -1.30851
SUOX sulfite oxidase -1.30833
THOC7 THO complex 7 -1.29859
DSCAML1 Down syndrome cell adhesion molecule like 1 -1.29719
SNRPG small nuclear ribonucleoprotein polypeptide G -1.29084
LHB luteinizing hormone beta polypeptide -1.28847
RNF181 ring finger protein 181 -1.28725
POM121C POM121 transmembrane nucleoporin C -1.28293
POP7 processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae) -1.28071
RPSAP9 ribosomal protein SA pseudogene 9 -1.28045
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) -1.27812
RPS19 ribosomal protein S19 -1.27402
ARHGEF25 Rho guanine nucleotide exchange factor (GEF) 25 -1.27323
MYC v-myc avian myelocytomatosis viral oncogene homolog -1.27245
PHKB phosphorylase kinase, beta -1.27224
AKT2 v-akt murine thymoma viral oncogene homolog 2 -1.27155
CDC25B cell division cycle 25B -1.26989
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B -1.26156
SEPHS1 selenophosphate synthetase 1 -1.25955
AKAP14 A kinase (PRKA) anchor protein 14 -1.25734
KLF15 Kruppel-like factor 15 -1.25397
ABLIM1 actin binding LIM protein 1 -1.24891
P2RY13 purinergic receptor P2Y, G-protein coupled, 13 -1.24819
PDPK1 3-phosphoinositide dependent protein kinase 1 -1.24424
RPL23A ribosomal protein L23a -1.23637
COX7C cytochrome c oxidase subunit VIIc -1.23558
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 -1.23403
SYT10 synaptotagmin X -1.23337
KDM1A lysine (K)-specific demethylase 1A -1.23258
CSTB cystatin B (stefin B) -1.22973
MMP2 matrix metallopeptidase 2 -1.22366
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4 -1.22106
CPSF3 cleavage and polyadenylation specific factor 3, 73kDa -1.21646
CLEC4D C-type lectin domain family 4, member D -1.21272
SMC2 structural maintenance of chromosomes 2 -1.2067
RPS27A ribosomal protein S27a -1.20236
SRP19 signal recognition particle 19kDa -1.19824
AMELX amelogenin, X-linked -1.19801
PRDM16 PR domain containing 16 -1.19777
MMD2 monocyte to macrophage differentiation-associated 2 -1.19744
KLHL4 kelch-like family member 4 -1.19517
YPEL2 yippee-like 2 (Drosophila) -1.19445
UROD uroporphyrinogen decarboxylase -1.18768
RARB retinoic acid receptor, beta -1.18512
TRIM63 tripartite motif containing 63, E3 ubiquitin protein ligase -1.18329
GPX4 glutathione peroxidase 4 -1.17989
MMP8 matrix metallopeptidase 8 -1.17888
THOP1 thimet oligopeptidase 1 -1.17692
PRSS48 protease, serine, 48 -1.17666
ZNF22 zinc finger protein 22 -1.1763
IFNA6 interferon, alpha 6 -1.17458
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 -1.17425
ZNF432 zinc finger protein 432 -1.17321
TFCP2L1 transcription factor CP2-like 1 -1.1677
BCAP29 B-cell receptor-associated protein 29 -1.16665
ATP6V0E2 ATPase, H+ transporting V0 subunit e2 -1.16525
KLF13 Kruppel-like factor 13 -1.15709
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) -1.15483
USP17L5 ubiquitin specific peptidase 17-like family member 5 -1.1448
CAPN11 calpain 11 -1.14281
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 -1.1415
AEBP1 AE binding protein 1 -1.14101
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8 -1.13504
ATM ATM serine/threonine kinase -1.13488
ZNF148 zinc finger protein 148 -1.1333
ARID3A AT rich interactive domain 3A (BRIGHT-like) -1.1254
CD8B CD8b molecule -1.12446
PNPLA5 patatin-like phospholipase domain containing 5 -1.12213
HIST2H2AC histone cluster 2, H2ac -1.12177
MRPS21 mitochondrial ribosomal protein S21 -1.11902
TRPV5 transient receptor potential cation channel, subfamily V, member 5 -1.11769
SMAD4 SMAD family member 4 -1.11769
ZNF454 zinc finger protein 454 -1.11709
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 -1.11644
HGS hepatocyte growth factor-regulated tyrosine kinase substrate -1.11438
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 -1.11269
OR2J2 olfactory receptor, family 2, subfamily J, member 2 -1.11246
EME1 essential meiotic structure-specific endonuclease 1 -1.11115
ADRA2A adrenoceptor alpha 2A -1.1077
LARS leucyl-tRNA synthetase -1.09964
RALBP1 ralA binding protein 1 -1.0968
RPL5 ribosomal protein L5 -1.09012
RTP1 receptor (chemosensory) transporter protein 1 -1.08959
MS4A6E membrane-spanning 4-domains, subfamily A, member 6E -1.08622
RTEL1-TNFRSF6B RTEL1-TNFRSF6B readthrough (NMD candidate) -1.0847
NUP54 nucleoporin 54kDa -1.08428
MED4 mediator complex subunit 4 -1.08398
NFX1 nuclear transcription factor, X-box binding 1 -1.08381
BRD4 bromodomain containing 4 -1.08247
MRPL38 mitochondrial ribosomal protein L38 -1.07496
TEC tec protein tyrosine kinase -1.07395
CCL21 chemokine (C-C motif) ligand 21 -1.06996
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2 -1.06916
FUT11 fucosyltransferase 11 (alpha (1,3) fucosyltransferase) -1.06591
POM121 POM121 transmembrane nucleoporin -1.06394
DDX49 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 -1.06013
KARS lysyl-tRNA synthetase -1.05945
DLAT dihydrolipoamide S-acetyltransferase -1.05927
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 -1.05857
RAB11FIP5 RAB11 family interacting protein 5 (class I) -1.05548
FIP1L1 factor interacting with PAPOLA and CPSF1 -1.05384
SLC13A3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 -1.05081
GUSBP1 glucuronidase, beta pseudogene 1 -1.04708
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa -1.04542
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -1.04535
RBM8A RNA binding motif protein 8A -1.04407
IMMP1L IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae) -1.04267
RBM22 RNA binding motif protein 22 -1.04086
MED12 mediator complex subunit 12 -1.03751
SF3B4 splicing factor 3b, subunit 4, 49kDa -1.03737
NUPL1 nucleoporin like 1 -1.03632
P3H1 prolyl 3-hydroxylase 1 -1.03582
TNFAIP8L2-SCNM1 TNFAIP8L2-SCNM1 readthrough -1.03261
CLIP1 CAP-GLY domain containing linker protein 1 -1.02961
INTS3 integrator complex subunit 3 -1.02918
OR4K17 olfactory receptor, family 4, subfamily K, member 17 -1.02394
CAP2 CAP, adenylate cyclase-associated protein, 2 (yeast) -1.02336
RPS6 ribosomal protein S6 -1.02161
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase -1.02083
UQCRC1 ubiquinol-cytochrome c reductase core protein I -1.01962
KISS1 KiSS-1 metastasis-suppressor -1.01697
OR2L13 olfactory receptor, family 2, subfamily L, member 13 -1.01677
PBX1 pre-B-cell leukemia homeobox 1 -1.01587
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1 -1.01534
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) -1.01332
HSPE1-MOB4 HSPE1-MOB4 readthrough -1.01302
MYEF2 myelin expression factor 2 -1.00976
MET MET proto-oncogene, receptor tyrosine kinase -1.00913
GIF gastric intrinsic factor (vitamin B synthesis) -1.0039
L3MBTL4 l(3)mbt-like 4 (Drosophila) -1.00374
USP17L4 ubiquitin specific peptidase 17-like family member 4 -1.00332
ZFHX3 zinc finger homeobox 3 -1.00267