| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Baicalin perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Baicalin_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| INTS6 | integrator complex subunit 6 | 0.0596105 |
| VCL | vinculin | 0.0595662 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.057324 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0541558 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0484108 |
| LMO7 | LIM domain 7 | 0.0474608 |
| CANX | calnexin | 0.045778 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0319828 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0315917 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0309037 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0297663 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | 0.0293366 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0286708 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0283185 |
| AREG | amphiregulin | 0.0282448 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0282028 |
| ASPH | aspartate beta-hydroxylase | 0.0279731 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0276888 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0274135 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0270513 |
| TUFT1 | tuftelin 1 | 0.0258522 |
| PCBP2 | poly(rC) binding protein 2 | 0.0252399 |
| TOX3 | TOX high mobility group box family member 3 | 0.024959 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0244725 |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like | 0.0244607 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0242264 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0232758 |
| CTBP2 | C-terminal binding protein 2 | 0.0229159 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0227465 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0226725 |
| VEGFA | vascular endothelial growth factor A | 0.0224319 |
| KIF16B | kinesin family member 16B | 0.0223065 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0221787 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0218704 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0217359 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0216472 |
| PADI1 | peptidyl arginine deiminase, type I | 0.0213765 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0213445 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0213189 |
| ERBIN | erbb2 interacting protein | 0.0212742 |
| MCL1 | myeloid cell leukemia 1 | 0.0211782 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0211386 |
| TUT7 | terminal uridylyl transferase 7 | 0.0211082 |
| TRIM2 | tripartite motif containing 2 | 0.0210545 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0210356 |
| WEE1 | WEE1 G2 checkpoint kinase | 0.0210213 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0208172 |
| SPATA13 | spermatogenesis associated 13 | 0.020789 |
| NPSR1 | neuropeptide S receptor 1 | 0.0207251 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0205301 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0205228 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0204241 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0202216 |
| COG3 | component of oligomeric golgi complex 3 | 0.0201489 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0199219 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0197203 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0196175 |
| EPHB2 | EPH receptor B2 | 0.0195596 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0194132 |
| KAZN | kazrin, periplakin interacting protein | 0.0192033 |
| SUMF1 | sulfatase modifying factor 1 | 0.0191406 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0189932 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0189215 |
| STX18 | syntaxin 18 | 0.0189067 |
| ETV6 | ets variant 6 | 0.0188527 |
| EFNB2 | ephrin-B2 | 0.0187008 |
| RAB21 | RAB21, member RAS oncogene family | 0.0186683 |
| LAMB3 | laminin, beta 3 | 0.0186554 |
| SQSTM1 | sequestosome 1 | 0.0185443 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0184889 |
| SLK | STE20-like kinase | 0.0184752 |
| ADIPOR2 | adiponectin receptor 2 | 0.0184602 |
| FRK | fyn-related Src family tyrosine kinase | 0.0183341 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0181667 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0181218 |
| SMAD3 | SMAD family member 3 | 0.0179909 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0179505 |
| LONRF3 | LON peptidase N-terminal domain and ring finger 3 | 0.017871 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0178403 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0176321 |
| NUP98 | nucleoporin 98kDa | 0.0176059 |
| YEATS2 | YEATS domain containing 2 | 0.0175111 |
| APP | amyloid beta (A4) precursor protein | 0.0175029 |
| CLTC | clathrin, heavy chain (Hc) | 0.0174838 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | 0.0173463 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0172874 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.0171118 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0170945 |
| ECT2 | epithelial cell transforming 2 | 0.0169489 |
| SSBP3 | single stranded DNA binding protein 3 | 0.0169175 |
| PMM2 | phosphomannomutase 2 | 0.0167987 |
| GOLGA3 | golgin A3 | 0.016747 |
| CCDC146 | coiled-coil domain containing 146 | 0.01667 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0166546 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0165212 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0164693 |
| JMJD1C | jumonji domain containing 1C | 0.0164685 |
| GRK3 | G protein-coupled receptor kinase 3 | 0.0164675 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0163825 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0163482 |
| Symbol | Name | Standardized Value |
|---|---|---|
| B2M | beta-2-microglobulin | -0.241585 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.229196 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.116399 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.103481 |
| HLA-B | major histocompatibility complex, class I, B | -0.0904428 |
| EGR1 | early growth response 1 | -0.0864495 |
| LCN2 | lipocalin 2 | -0.0805207 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0798467 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0776775 |
| NCKAP5 | NCK-associated protein 5 | -0.0771448 |
| RPS6 | ribosomal protein S6 | -0.0761213 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0744831 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0727427 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0724965 |
| PKM | pyruvate kinase, muscle | -0.0680906 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0674396 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0631637 |
| RPLP1 | ribosomal protein, large, P1 | -0.0626348 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0624191 |
| FTL | ferritin, light polypeptide | -0.0554222 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0534356 |
| TXNIP | thioredoxin interacting protein | -0.0527353 |
| RPS19 | ribosomal protein S19 | -0.052288 |
| CCNL1 | cyclin L1 | -0.0516734 |
| CST3 | cystatin C | -0.0514056 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0508321 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0496917 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0491634 |
| IRF1 | interferon regulatory factor 1 | -0.0487434 |
| S100A10 | S100 calcium binding protein A10 | -0.0480661 |
| RPL23 | ribosomal protein L23 | -0.0477506 |
| ITGA6 | integrin, alpha 6 | -0.0463706 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0452839 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0444824 |
| RUNX1 | runt-related transcription factor 1 | -0.0425446 |
| MT2A | metallothionein 2A | -0.0411834 |
| RPL28 | ribosomal protein L28 | -0.0410809 |
| PERP | PERP, TP53 apoptosis effector | -0.0408541 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0407289 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0396411 |
| RPLP2 | ribosomal protein, large, P2 | -0.0396038 |
| RPL12 | ribosomal protein L12 | -0.0393072 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0392229 |
| TMEM123 | transmembrane protein 123 | -0.0377547 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0371818 |
| CSTB | cystatin B (stefin B) | -0.0369545 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0364446 |
| DSTN | destrin (actin depolymerizing factor) | -0.035817 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0356542 |
| IFNGR1 | interferon gamma receptor 1 | -0.0354658 |
| LOC112694756 | uncharaterized LOC112694756 | -0.035173 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0351265 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0342131 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0335175 |
| RPS8 | ribosomal protein S8 | -0.0334698 |
| RPS27 | ribosomal protein S27 | -0.0333132 |
| MX2 | MX dynamin-like GTPase 2 | -0.0332155 |
| TPI1 | triosephosphate isomerase 1 | -0.0332033 |
| TMSB10 | thymosin beta 10 | -0.0330576 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0330505 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0326402 |
| UBC | ubiquitin C | -0.0325794 |
| NDRG1 | N-myc downstream regulated 1 | -0.032554 |
| ABLIM1 | actin binding LIM protein 1 | -0.0320344 |
| TXNRD1 | thioredoxin reductase 1 | -0.0319259 |
| RPL19 | ribosomal protein L19 | -0.0319138 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0312374 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.031219 |
| CDCP1 | CUB domain containing protein 1 | -0.0309806 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0307141 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0303966 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0300536 |
| GNAS | GNAS complex locus | -0.0296423 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0295498 |
| TMEM165 | transmembrane protein 165 | -0.0294061 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0293076 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0292366 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0287517 |
| RPL32 | ribosomal protein L32 | -0.0285638 |
| KDM5A | lysine (K)-specific demethylase 5A | -0.0281106 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0280285 |
| MKI67 | marker of proliferation Ki-67 | -0.028017 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0278586 |
| RPL36 | ribosomal protein L36 | -0.0278375 |
| SFTPA2 | surfactant protein A2 | -0.0276118 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0275732 |
| MT1X | metallothionein 1X | -0.0275727 |
| BPTF | bromodomain PHD finger transcription factor | -0.0274924 |
| RPL35A | ribosomal protein L35a | -0.026924 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0268898 |
| MTDH | metadherin | -0.0265662 |
| NUCB2 | nucleobindin 2 | -0.0265602 |
| OARD1 | O-acyl-ADP-ribose deacylase 1 | -0.0264852 |
| RPL36A | ribosomal protein L36a | -0.0263619 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0261416 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0257333 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.0256236 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0255599 |
| HLA-C | major histocompatibility complex, class I, C | -0.0255265 |
| SERF2 | small EDRK-rich factor 2 | -0.0254928 |