| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Baicalin perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Baicalin_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.353135 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.15773 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.118639 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0889703 |
| VEGFA | vascular endothelial growth factor A | 0.0848456 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0829804 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0823937 |
| PLEC | plectin | 0.0786133 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0761824 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0659224 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.0606406 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.060169 |
| CADM1 | cell adhesion molecule 1 | 0.0584847 |
| VMP1 | vacuole membrane protein 1 | 0.0571639 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0568278 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0519564 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0511059 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0458025 |
| ATP13A3 | ATPase type 13A3 | 0.0453101 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0444375 |
| CYB5R3 | cytochrome b5 reductase 3 | 0.0434655 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0419566 |
| FLNA | filamin A, alpha | 0.0396691 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0389515 |
| RPL35A | ribosomal protein L35a | 0.0370644 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0364773 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.035796 |
| CD44 | CD44 molecule (Indian blood group) | 0.0324653 |
| MRTFA | myocardin related transcription factor A | 0.0323436 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0317417 |
| ADM | adrenomedullin | 0.0315468 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0312356 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0312325 |
| JAG1 | jagged 1 | 0.0312255 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0305098 |
| HYOU1 | hypoxia up-regulated 1 | 0.0298679 |
| FTL | ferritin, light polypeptide | 0.0297455 |
| COPA | coatomer protein complex, subunit alpha | 0.0294081 |
| SETD5 | SET domain containing 5 | 0.0290059 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0289712 |
| SPAG9 | sperm associated antigen 9 | 0.0289425 |
| IL6 | interleukin 6 | 0.0280237 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0270116 |
| YAP1 | Yes-associated protein 1 | 0.0268265 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0267118 |
| SDC2 | syndecan 2 | 0.0264483 |
| RPS6 | ribosomal protein S6 | 0.0259478 |
| BRD2 | bromodomain containing 2 | 0.0258589 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0258294 |
| RASA2 | RAS p21 protein activator 2 | 0.02561 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0246838 |
| RPS25 | ribosomal protein S25 | 0.0244906 |
| HLA-A | major histocompatibility complex, class I, A | 0.0240494 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0238799 |
| TFG | TRK-fused gene | 0.0238556 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0238015 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0237058 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0235559 |
| RND3 | Rho family GTPase 3 | 0.023375 |
| CCNY | cyclin Y | 0.0232631 |
| RPL37A | ribosomal protein L37a | 0.0223631 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0222883 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0222438 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.022098 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0220902 |
| INTS6 | integrator complex subunit 6 | 0.0216606 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0216123 |
| COL5A3 | collagen, type V, alpha 3 | 0.0214816 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0212382 |
| MSN | moesin | 0.0205349 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0205198 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0203458 |
| WTAP | Wilms tumor 1 associated protein | 0.0199189 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0198467 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0197074 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.019641 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0196401 |
| MYO1B | myosin IB | 0.0195706 |
| RPS11 | ribosomal protein S11 | 0.019141 |
| STC2 | stanniocalcin 2 | 0.0190443 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0189444 |
| IRF1 | interferon regulatory factor 1 | 0.0188141 |
| QKI | QKI, KH domain containing, RNA binding | 0.0187516 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0186308 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | 0.0185362 |
| SRSF3 | serine/arginine-rich splicing factor 3 | 0.0185055 |
| RNF145 | ring finger protein 145 | 0.0185038 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.018352 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0183163 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0182107 |
| RPS17 | ribosomal protein S17 | 0.0180279 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.0180167 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.017986 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0179683 |
| FMNL2 | formin-like 2 | 0.0178487 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0177444 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0176703 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.017453 |
| VEGFC | vascular endothelial growth factor C | 0.017423 |
| GNG12 | guanine nucleotide binding protein (G protein), gamma 12 | 0.0173367 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.210545 |
| NDRG1 | N-myc downstream regulated 1 | -0.144427 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.139486 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.123915 |
| VIM | vimentin | -0.11039 |
| CDH13 | cadherin 13 | -0.0935337 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.090581 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0821918 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0791818 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0749351 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0708651 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0700101 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0663418 |
| RRBP1 | ribosome binding protein 1 | -0.0651436 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.062396 |
| ENO1 | enolase 1, (alpha) | -0.0611949 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0600667 |
| STC1 | stanniocalcin 1 | -0.0562021 |
| AHNAK | AHNAK nucleoprotein | -0.0554806 |
| MT1X | metallothionein 1X | -0.0536819 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0509685 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0508968 |
| COL5A1 | collagen, type V, alpha 1 | -0.0500954 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.049506 |
| CALR | calreticulin | -0.049396 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0469488 |
| PDE10A | phosphodiesterase 10A | -0.0463865 |
| ASPH | aspartate beta-hydroxylase | -0.0456519 |
| TMSB4X | thymosin beta 4, X-linked | -0.0453655 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0447491 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0435671 |
| CENPF | centromere protein F, 350/400kDa | -0.0434854 |
| CANX | calnexin | -0.0433507 |
| VCAN | versican | -0.0417898 |
| RUNX1 | runt-related transcription factor 1 | -0.0415327 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0405288 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0398284 |
| PRELID2 | PRELI domain containing 2 | -0.0397689 |
| TPM4 | tropomyosin 4 | -0.0391847 |
| DST | dystonin | -0.038933 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.03881 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0383945 |
| CAVIN1 | caveolae associated protein 1 | -0.0382227 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0380073 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0374431 |
| NAV1 | neuron navigator 1 | -0.0373523 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0365123 |
| SBF2 | SET binding factor 2 | -0.0362779 |
| CALU | calumenin | -0.0361223 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0337562 |
| SH3PXD2B | SH3 and PX domains 2B | -0.0329658 |
| ANXA2 | annexin A2 | -0.0323663 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0321066 |
| LOXL2 | lysyl oxidase-like 2 | -0.0319065 |
| ATXN1 | ataxin 1 | -0.0317378 |
| COL1A1 | collagen, type I, alpha 1 | -0.0315525 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0313334 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0312924 |
| H1-0 | H1.0 linker histone | -0.0312584 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0308838 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0306636 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0305811 |
| PGK1 | phosphoglycerate kinase 1 | -0.0298505 |
| BNC2 | basonuclin 2 | -0.0297523 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0295968 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.029533 |
| EFNA5 | ephrin-A5 | -0.0295029 |
| FRMD4A | FERM domain containing 4A | -0.0291916 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0283099 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0281449 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0273017 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0272756 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0270025 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0269311 |
| TMSB10 | thymosin beta 10 | -0.0267542 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0266802 |
| MKI67 | marker of proliferation Ki-67 | -0.0263479 |
| PRR16 | proline rich 16 | -0.0262229 |
| TPX2 | TPX2, microtubule-associated | -0.0260363 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0254782 |
| EXOC4 | exocyst complex component 4 | -0.0252771 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0250695 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0248181 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0247568 |
| NF1 | neurofibromin 1 | -0.024377 |
| RLF | rearranged L-myc fusion | -0.0242403 |
| MAP1B | microtubule-associated protein 1B | -0.024156 |
| FOXP1 | forkhead box P1 | -0.0240624 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0240573 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.0240034 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0235779 |
| YEATS2 | YEATS domain containing 2 | -0.02352 |
| TMEM263 | transmembrane protein 263 | -0.0229067 |
| CENPE | centromere protein E, 312kDa | -0.0229052 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | -0.0228796 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0227231 |
| KIAA1328 | KIAA1328 | -0.0225512 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0220419 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.021993 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0218394 |
