| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Baicalin perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Baicalin_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VEGFA | vascular endothelial growth factor A | 0.0905979 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0746651 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0725938 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0689038 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0675786 |
| GOLGA4 | golgin A4 | 0.0661504 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.065902 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0646096 |
| LMO7 | LIM domain 7 | 0.0606882 |
| HYOU1 | hypoxia up-regulated 1 | 0.0568521 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0547942 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0514781 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0505003 |
| PCBP2 | poly(rC) binding protein 2 | 0.0480219 |
| ITGA6 | integrin, alpha 6 | 0.0462476 |
| TNIK | TRAF2 and NCK interacting kinase | 0.041185 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0410079 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0409105 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0400818 |
| KLHL29 | kelch-like family member 29 | 0.0396544 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.038878 |
| PLEC | plectin | 0.0384514 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0372961 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0366014 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0353193 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0341686 |
| VMP1 | vacuole membrane protein 1 | 0.0341164 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0331483 |
| FLNB | filamin B, beta | 0.0326214 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0317012 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.031555 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.0315344 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0310365 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0310267 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0308587 |
| POTEF | POTE ankyrin domain family, member F | 0.0306324 |
| FAM13A | family with sequence similarity 13, member A | 0.0303515 |
| MYOF | myoferlin | 0.0301539 |
| TPM3 | tropomyosin 3 | 0.0294333 |
| ANXA1 | annexin A1 | 0.028368 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.028137 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0274439 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.026674 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0261064 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0260118 |
| MYO5B | myosin VB | 0.0259961 |
| DSPP | dentin sialophosphoprotein | 0.0255916 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0254999 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0253251 |
| SNX13 | sorting nexin 13 | 0.0249381 |
| NDRG1 | N-myc downstream regulated 1 | 0.0248452 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0247339 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0247082 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0245554 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0245283 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0238782 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0238463 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.023685 |
| PGM3 | phosphoglucomutase 3 | 0.0236683 |
| SETD5 | SET domain containing 5 | 0.0233915 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0233773 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0232121 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0230961 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0229898 |
| HELZ | helicase with zinc finger | 0.022876 |
| ITGB4 | integrin, beta 4 | 0.0228213 |
| MCU | mitochondrial calcium uniporter | 0.0227425 |
| TRAM1 | translocation associated membrane protein 1 | 0.0224736 |
| COPA | coatomer protein complex, subunit alpha | 0.022221 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0219685 |
| HM13 | histocompatibility (minor) 13 | 0.0217383 |
| SLTM | SAFB-like, transcription modulator | 0.0216232 |
| SLK | STE20-like kinase | 0.0215899 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0214662 |
| HKDC1 | hexokinase domain containing 1 | 0.0214267 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0212984 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0212604 |
| COG5 | component of oligomeric golgi complex 5 | 0.0211811 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0209754 |
| SRP54 | signal recognition particle 54kDa | 0.0208973 |
| TMF1 | TATA element modulatory factor 1 | 0.0208656 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0208502 |
| PMM2 | phosphomannomutase 2 | 0.0206543 |
| TRAK1 | trafficking protein, kinesin binding 1 | 0.0204105 |
| TES | testin LIM domain protein | 0.020289 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.0202218 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.020084 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0200737 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0197538 |
| AGR3 | anterior gradient 3 | 0.0196939 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0195804 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0193985 |
| CCNY | cyclin Y | 0.0193797 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | 0.0193116 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.01919 |
| CLTC | clathrin, heavy chain (Hc) | 0.0191101 |
| KIF16B | kinesin family member 16B | 0.0191058 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0190695 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0190564 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.019043 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.205856 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.173049 |
| PTMA | prothymosin, alpha | -0.126892 |
| RPL35A | ribosomal protein L35a | -0.112424 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.107289 |
| RPL23 | ribosomal protein L23 | -0.103585 |
| RPS19 | ribosomal protein S19 | -0.0944424 |
| RPLP1 | ribosomal protein, large, P1 | -0.0928502 |
| FTL | ferritin, light polypeptide | -0.074309 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0729995 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0690673 |
| B2M | beta-2-microglobulin | -0.0681322 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0663894 |
| RPL19 | ribosomal protein L19 | -0.0659476 |
| S100A9 | S100 calcium binding protein A9 | -0.0652865 |
| RPS21 | ribosomal protein S21 | -0.0649853 |
| RPS24 | ribosomal protein S24 | -0.0644179 |
| RPL26 | ribosomal protein L26 | -0.0639613 |
| RPS6 | ribosomal protein S6 | -0.0637452 |
| S100A10 | S100 calcium binding protein A10 | -0.0636009 |
| RPS8 | ribosomal protein S8 | -0.0625284 |
| RPS25 | ribosomal protein S25 | -0.0607177 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.059406 |
| S100P | S100 calcium binding protein P | -0.0579747 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0573645 |
| ACTG1 | actin gamma 1 | -0.0555651 |
| EPCAM | epithelial cell adhesion molecule | -0.0533842 |
| RPL38 | ribosomal protein L38 | -0.0527983 |
| RPL34 | ribosomal protein L34 | -0.0527712 |
| RPL12 | ribosomal protein L12 | -0.0523595 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0519162 |
| RPS29 | ribosomal protein S29 | -0.0488939 |
| RRBP1 | ribosome binding protein 1 | -0.0484555 |
| RPS3 | ribosomal protein S3 | -0.0480742 |
| RPL32 | ribosomal protein L32 | -0.046805 |
| RPLP2 | ribosomal protein, large, P2 | -0.0452975 |
| RPL9 | ribosomal protein L9 | -0.0445292 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.0429383 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0423975 |
| ATF5 | activating transcription factor 5 | -0.0423733 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0422899 |
| RPL28 | ribosomal protein L28 | -0.0421661 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0416688 |
| RPS27A | ribosomal protein S27a | -0.041394 |
| RPL36A | ribosomal protein L36a | -0.0403668 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0403584 |
| RPL7A | ribosomal protein L7a | -0.039651 |
| HLA-E | major histocompatibility complex, class I, E | -0.0395787 |
| RPL27 | ribosomal protein L27 | -0.0394401 |
| RPL35 | ribosomal protein L35 | -0.0388039 |
| H3-3B | H3.3 histone B | -0.0386282 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0383586 |
| RPL37A | ribosomal protein L37a | -0.0373494 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.036749 |
| RPL11 | ribosomal protein L11 | -0.0366411 |
| RPL36 | ribosomal protein L36 | -0.0363955 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0363478 |
| HLA-C | major histocompatibility complex, class I, C | -0.0359356 |
| SEC61G | Sec61 gamma subunit | -0.0352803 |
| HLA-B | major histocompatibility complex, class I, B | -0.0352155 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0331593 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0321741 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0320342 |
| RPS23 | ribosomal protein S23 | -0.0309806 |
| TUBB4B | tubulin, beta 4B class IVb | -0.030957 |
| SERF2 | small EDRK-rich factor 2 | -0.0307946 |
| RPS16 | ribosomal protein S16 | -0.0306193 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0302292 |
| RPS5 | ribosomal protein S5 | -0.0295688 |
| KLF6 | Kruppel-like factor 6 | -0.0294013 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0291473 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0291236 |
| LMNA | lamin A/C | -0.028984 |
| RPL5 | ribosomal protein L5 | -0.0288233 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.02873 |
| RPL31 | ribosomal protein L31 | -0.0287218 |
| EMP1 | epithelial membrane protein 1 | -0.0287043 |
| RPS15 | ribosomal protein S15 | -0.0284289 |
| RPS27 | ribosomal protein S27 | -0.0283893 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.028358 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0282426 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0282178 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0277728 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0275816 |
| RPS10 | ribosomal protein S10 | -0.0274239 |
| SELENOK | selenoprotein K | -0.0273613 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0269597 |
| GNAS | GNAS complex locus | -0.0269485 |
| HMGB1 | high mobility group box 1 | -0.0268469 |
| KRT8 | keratin 8, type II | -0.0268277 |
| AGR2 | anterior gradient 2 | -0.0266961 |
| RPL36AL | ribosomal protein L36a-like | -0.0265214 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0263328 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0256029 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.0255926 |
| H1-0 | H1.0 linker histone | -0.0253951 |
| RPS11 | ribosomal protein S11 | -0.0252451 |
| RPL30 | ribosomal protein L30 | -0.025141 |
| UBB | ubiquitin B | -0.0250938 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.024914 |