| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Baicalin perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Baicalin_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DST | dystonin | 0.167935 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.161988 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.130152 |
| SPAG9 | sperm associated antigen 9 | 0.11324 |
| CAPRIN2 | caprin family member 2 | 0.0836877 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0758154 |
| TMSB4X | thymosin beta 4, X-linked | 0.0669979 |
| PTMA | prothymosin, alpha | 0.064043 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0640429 |
| FMNL2 | formin-like 2 | 0.0636117 |
| VCL | vinculin | 0.0609019 |
| RUNX1 | runt-related transcription factor 1 | 0.0600848 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0569825 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0542653 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0523849 |
| RCOR1 | REST corepressor 1 | 0.0518355 |
| OGA | O-GlcNAcase | 0.0472823 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0459328 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0458752 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0447287 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0446538 |
| CALR | calreticulin | 0.0433288 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0432897 |
| TOP1 | topoisomerase (DNA) I | 0.0431709 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0420544 |
| RPS12 | ribosomal protein S12 | 0.0412606 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0408717 |
| TXNIP | thioredoxin interacting protein | 0.0407815 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0406978 |
| CD44 | CD44 molecule (Indian blood group) | 0.0405405 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0402171 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0397139 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0393294 |
| EZR | ezrin | 0.0392548 |
| ZNF292 | zinc finger protein 292 | 0.0392346 |
| PRELID2 | PRELI domain containing 2 | 0.0391515 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0390707 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0389599 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0385699 |
| SQSTM1 | sequestosome 1 | 0.038403 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0383576 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0382539 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0377284 |
| APP | amyloid beta (A4) precursor protein | 0.0372086 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0368334 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0365487 |
| MYOF | myoferlin | 0.0361626 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0360517 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0358917 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0357238 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0355023 |
| RBM39 | RNA binding motif protein 39 | 0.0345961 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0341691 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.033592 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0335475 |
| STAG2 | stromal antigen 2 | 0.03327 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.032917 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0326054 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0323643 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0321235 |
| PLK2 | polo-like kinase 2 | 0.0320201 |
| FNIP1 | folliculin interacting protein 1 | 0.0317405 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0317376 |
| NUP58 | nucleoporin 58 | 0.0316395 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0315212 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.031473 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.031432 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0312147 |
| TNS3 | tensin 3 | 0.0311345 |
| SMAD3 | SMAD family member 3 | 0.0310897 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0308274 |
| CANX | calnexin | 0.0307991 |
| QKI | QKI, KH domain containing, RNA binding | 0.0307136 |
| VMP1 | vacuole membrane protein 1 | 0.0306175 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0303285 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0302194 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0297214 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0296899 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0296069 |
| KLF6 | Kruppel-like factor 6 | 0.0294779 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0293314 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0292856 |
| TP63 | tumor protein p63 | 0.029248 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0292352 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0291607 |
| JMJD1C | jumonji domain containing 1C | 0.0291292 |
| PCBP2 | poly(rC) binding protein 2 | 0.0288845 |
| SDC4 | syndecan 4 | 0.0287028 |
| CDC73 | cell division cycle 73 | 0.0286172 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0283532 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.028351 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0283045 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0279148 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0279067 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.027865 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0276225 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0274139 |
| ACTN1 | actinin, alpha 1 | 0.0272777 |
| ZNF207 | zinc finger protein 207 | 0.0271211 |
| HELZ | helicase with zinc finger | 0.0270512 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.155327 |
| VIM | vimentin | -0.148402 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.109214 |
| TXNRD1 | thioredoxin reductase 1 | -0.0896841 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0580327 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0526508 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0465444 |
| MT1E | metallothionein 1E | -0.0441242 |
| POTEF | POTE ankyrin domain family, member F | -0.0410097 |
| RAI1 | retinoic acid induced 1 | -0.0395514 |
| HMGA1 | high mobility group AT-hook 1 | -0.0385788 |
| SRGN | serglycin | -0.0356181 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0354322 |
| RPS6 | ribosomal protein S6 | -0.0351551 |
| ACTG1 | actin gamma 1 | -0.0348141 |
| EMP1 | epithelial membrane protein 1 | -0.034778 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0335627 |
| PRDX1 | peroxiredoxin 1 | -0.0334758 |
| RPS23 | ribosomal protein S23 | -0.0330251 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0327778 |
| UPP1 | uridine phosphorylase 1 | -0.0318843 |
| NAV2 | neuron navigator 2 | -0.031808 |
| MT1X | metallothionein 1X | -0.0309664 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0304338 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0295758 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0292229 |
| ANXA1 | annexin A1 | -0.0290687 |
| FTL | ferritin, light polypeptide | -0.0287669 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0278324 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0272593 |
| RPLP2 | ribosomal protein, large, P2 | -0.02692 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0264021 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0263994 |
| RPL7A | ribosomal protein L7a | -0.0257759 |
| RPL31 | ribosomal protein L31 | -0.0248031 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0247532 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.024506 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0244599 |
| USP34 | ubiquitin specific peptidase 34 | -0.0238165 |
| RPL5 | ribosomal protein L5 | -0.02326 |
| CDCP1 | CUB domain containing protein 1 | -0.0231464 |
| RCAN1 | regulator of calcineurin 1 | -0.0231044 |
| RPS19 | ribosomal protein S19 | -0.0222899 |
| S100A11 | S100 calcium binding protein A11 | -0.0220315 |
| ANGPTL4 | angiopoietin-like 4 | -0.022011 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0218826 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0205582 |
| RPL23 | ribosomal protein L23 | -0.0204357 |
| RPL28 | ribosomal protein L28 | -0.0202984 |
| TAPBP | TAP binding protein (tapasin) | -0.0198602 |
| ERCC6L2 | excision repair cross-complementation group 6-like 2 | -0.019811 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0197747 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0192414 |
| RPL27 | ribosomal protein L27 | -0.0191869 |
| RPS24 | ribosomal protein S24 | -0.0190603 |
| DARS1 | aspartyl-tRNA synthetase 1 | -0.0187826 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -0.018503 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0181445 |
| RPS8 | ribosomal protein S8 | -0.0181439 |
| CEP170 | centrosomal protein 170kDa | -0.0180356 |
| UBXN4 | UBX domain protein 4 | -0.0180075 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0179831 |
| DOCK11 | dedicator of cytokinesis 11 | -0.0174149 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0173157 |
| FOSL1 | FOS-like antigen 1 | -0.0172521 |
| RPL35A | ribosomal protein L35a | -0.0172357 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0169995 |
| RPS15 | ribosomal protein S15 | -0.016916 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0168849 |
| MYADM | myeloid-associated differentiation marker | -0.016752 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0165082 |
| OSMR | oncostatin M receptor | -0.0162625 |
| FERMT1 | fermitin family member 1 | -0.0161119 |
| AREG | amphiregulin | -0.0159775 |
| RPL32 | ribosomal protein L32 | -0.0158168 |
| RPLP1 | ribosomal protein, large, P1 | -0.0155343 |
| CFAP299 | cilia and flagella associated protein 299 | -0.0153864 |
| DDX50 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 | -0.0152922 |
| S100A10 | S100 calcium binding protein A10 | -0.0152617 |
| RPLP0 | ribosomal protein, large, P0 | -0.0150972 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0150557 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0149278 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.014787 |
| RPS29 | ribosomal protein S29 | -0.0146358 |
| RPS5 | ribosomal protein S5 | -0.0142246 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | -0.0140183 |
| FBXO17 | F-box protein 17 | -0.0139804 |
| RPS25 | ribosomal protein S25 | -0.0139302 |
| CALD1 | caldesmon 1 | -0.0138577 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0138287 |
| PLIN3 | perilipin 3 | -0.0138123 |
| NHSL1 | NHS-like 1 | -0.0137169 |
| BMERB1 | bMERB domain containing 1 | -0.0137125 |
| KRT19 | keratin 19, type I | -0.0136199 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0135621 |
| ITGB4 | integrin, beta 4 | -0.0134173 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0133954 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.0133327 |
| COL5A2 | collagen, type V, alpha 2 | -0.0132575 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0131477 |