| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Baicalin perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Baicalin_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PCBP2 | poly(rC) binding protein 2 | 0.0848056 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0761719 |
| SMAD3 | SMAD family member 3 | 0.0642635 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0628534 |
| VEGFA | vascular endothelial growth factor A | 0.0547525 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0541192 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0525535 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0521443 |
| EFNA5 | ephrin-A5 | 0.0510633 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0504647 |
| NAV2 | neuron navigator 2 | 0.045747 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0410864 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0368443 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0362783 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0338914 |
| FAM20C | family with sequence similarity 20, member C | 0.0329456 |
| LOXL2 | lysyl oxidase-like 2 | 0.0306481 |
| RUNX1 | runt-related transcription factor 1 | 0.029264 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0291421 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0279238 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0276096 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.026912 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0265612 |
| TGM2 | transglutaminase 2 | 0.0263727 |
| RAD51B | RAD51 paralog B | 0.0260701 |
| PRELID2 | PRELI domain containing 2 | 0.0253908 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0253023 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0249583 |
| MCL1 | myeloid cell leukemia 1 | 0.0247603 |
| EGFR | epidermal growth factor receptor | 0.0238949 |
| SEPTIN9 | septin 9 | 0.0237724 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0230708 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.022892 |
| INTS6 | integrator complex subunit 6 | 0.0227824 |
| STK38L | serine/threonine kinase 38 like | 0.0220028 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0219062 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0209365 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0206567 |
| CEP250 | centrosomal protein 250kDa | 0.02063 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0202241 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0197808 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0196544 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0195734 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0194588 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0193648 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0193127 |
| ATXN1 | ataxin 1 | 0.0193107 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0189434 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0187873 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0184845 |
| SIK3 | SIK family kinase 3 | 0.0184755 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0182597 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0180736 |
| MYO10 | myosin X | 0.017979 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0178736 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0177663 |
| ANGPTL4 | angiopoietin-like 4 | 0.0174886 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0173213 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0170438 |
| VMP1 | vacuole membrane protein 1 | 0.0169718 |
| ZNF638 | zinc finger protein 638 | 0.0167736 |
| ECE1 | endothelin converting enzyme 1 | 0.0166124 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0160678 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0159189 |
| WLS | wntless Wnt ligand secretion mediator | 0.0156788 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0154362 |
| AUTS2 | autism susceptibility candidate 2 | 0.0154221 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.015233 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0152303 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0152 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0149905 |
| NOTCH2 | notch 2 | 0.0146074 |
| KSR1 | kinase suppressor of ras 1 | 0.0145465 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0144731 |
| EFCAB13 | EF-hand calcium binding domain 13 | 0.0144449 |
| NEBL | nebulette | 0.0141949 |
| EXOC6B | exocyst complex component 6B | 0.0140931 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0138414 |
| HDAC9 | histone deacetylase 9 | 0.0137439 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.013588 |
| KCTD16 | potassium channel tetramerization domain containing 16 | 0.0135086 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0134955 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0134158 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0132823 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.0130534 |
| PLEC | plectin | 0.0130298 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.012889 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0127101 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0127098 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | 0.0126508 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0126483 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0126012 |
| MAFK | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K | 0.0125129 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0124681 |
| FAM219A | family with sequence similarity 219, member A | 0.0124427 |
| TPM3 | tropomyosin 3 | 0.0123626 |
| CPNE1 | copine I | 0.0123465 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0122157 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0122074 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.012111 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.233465 |
| VIM | vimentin | -0.219173 |
| TMSB10 | thymosin beta 10 | -0.206814 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.115392 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.106289 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.104019 |
| FN1 | fibronectin 1 | -0.0927746 |
| FTL | ferritin, light polypeptide | -0.0913845 |
| PTMA | prothymosin, alpha | -0.088836 |
| STC1 | stanniocalcin 1 | -0.0822918 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0822176 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.082143 |
| S100A6 | S100 calcium binding protein A6 | -0.0813748 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0765099 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0700397 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0698051 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0683919 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0670621 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0666648 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0660607 |
| LOX | lysyl oxidase | -0.0658062 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0630945 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0596126 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0562757 |
| OSMR | oncostatin M receptor | -0.055974 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0539251 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0526294 |
| B2M | beta-2-microglobulin | -0.05038 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0501456 |
| GLCCI1 | glucocorticoid induced 1 | -0.0501041 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0497515 |
| ENO1 | enolase 1, (alpha) | -0.046405 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0462521 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0456803 |
| RPLP1 | ribosomal protein, large, P1 | -0.0452423 |
| IER3 | immediate early response 3 | -0.0431955 |
| S100A10 | S100 calcium binding protein A10 | -0.0431749 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0428408 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0428241 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0427773 |
| RPS21 | ribosomal protein S21 | -0.0427125 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.041601 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0413086 |
| RPS19 | ribosomal protein S19 | -0.0400069 |
| RPL35A | ribosomal protein L35a | -0.0387603 |
| TMSB4X | thymosin beta 4, X-linked | -0.0384447 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0383673 |
| VRK2 | vaccinia related kinase 2 | -0.0375075 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0374609 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0371325 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0366261 |
| RPL34 | ribosomal protein L34 | -0.0365383 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0362977 |
| RPLP2 | ribosomal protein, large, P2 | -0.0362708 |
| CD44 | CD44 molecule (Indian blood group) | -0.0361846 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0361534 |
| HLA-B | major histocompatibility complex, class I, B | -0.035547 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0354928 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0354699 |
| PRSS23 | protease, serine, 23 | -0.0352686 |
| RPS24 | ribosomal protein S24 | -0.03524 |
| GOLGA4 | golgin A4 | -0.0346863 |
| IL1B | interleukin 1, beta | -0.0341035 |
| CLMP | CXADR-like membrane protein | -0.0340175 |
| THBD | thrombomodulin | -0.0339537 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.033847 |
| SNX9 | sorting nexin 9 | -0.0337977 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0336093 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0327891 |
| H1-0 | H1.0 linker histone | -0.0327657 |
| MEF2A | myocyte enhancer factor 2A | -0.032517 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0320929 |
| TMEM131 | transmembrane protein 131 | -0.0319893 |
| AHNAK | AHNAK nucleoprotein | -0.0319869 |
| RIOK3 | RIO kinase 3 | -0.031604 |
| EGR1 | early growth response 1 | -0.0314087 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0312704 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0309214 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0307373 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0306023 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0305933 |
| MT2A | metallothionein 2A | -0.0305922 |
| RPS6 | ribosomal protein S6 | -0.0302505 |
| NUMB | numb homolog (Drosophila) | -0.029888 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0298405 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.029714 |
| CP | ceruloplasmin (ferroxidase) | -0.0295816 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0291945 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0291691 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.029098 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0290225 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0289854 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0288733 |
| RPL31 | ribosomal protein L31 | -0.0285699 |
| RPL32 | ribosomal protein L32 | -0.0283744 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0281199 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0275641 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0275284 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0273993 |
| TMEM263 | transmembrane protein 263 | -0.0273514 |