| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Baicalin perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Baicalin_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LAMB3 | laminin, beta 3 | 0.128301 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0930484 |
| EGFR | epidermal growth factor receptor | 0.0860169 |
| KRT17 | keratin 17, type I | 0.0768771 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0735336 |
| HDAC9 | histone deacetylase 9 | 0.0726415 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.072008 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.0706167 |
| CDK6 | cyclin-dependent kinase 6 | 0.0664332 |
| LAMC2 | laminin, gamma 2 | 0.0663714 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0661906 |
| OGA | O-GlcNAcase | 0.0651271 |
| EHBP1 | EH domain binding protein 1 | 0.0649761 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0631838 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0630158 |
| SMYD3 | SET and MYND domain containing 3 | 0.0616223 |
| AK1 | adenylate kinase 1 | 0.0604582 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0572492 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0567919 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0561013 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0560861 |
| AHNAK | AHNAK nucleoprotein | 0.0503222 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0501152 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0494464 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0485309 |
| APP | amyloid beta (A4) precursor protein | 0.0472227 |
| AEBP2 | AE binding protein 2 | 0.0469862 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0469859 |
| JMJD1C | jumonji domain containing 1C | 0.0465307 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0462402 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.045782 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0456812 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0448176 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0443506 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0441298 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0438594 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0438256 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0436241 |
| FLNB | filamin B, beta | 0.0435827 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0434718 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0429532 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0429454 |
| CMIP | c-Maf inducing protein | 0.0428513 |
| JMY | junction mediating and regulatory protein, p53 cofactor | 0.0426834 |
| BRD4 | bromodomain containing 4 | 0.042608 |
| RND3 | Rho family GTPase 3 | 0.0421828 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0418839 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0418576 |
| NDRG1 | N-myc downstream regulated 1 | 0.0411745 |
| RIGI | RNA sensor RIG-I | 0.0404856 |
| CANX | calnexin | 0.0403598 |
| BRD2 | bromodomain containing 2 | 0.0399928 |
| CHD4 | chromodomain helicase DNA binding protein 4 | 0.0396568 |
| CDCP1 | CUB domain containing protein 1 | 0.0394601 |
| ASPH | aspartate beta-hydroxylase | 0.0393521 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.0389697 |
| HS6ST3 | heparan sulfate 6-O-sulfotransferase 3 | 0.0385396 |
| RNF103-CHMP3 | RNF103-CHMP3 readthrough | 0.0378719 |
| PRKCA | protein kinase C, alpha | 0.0376698 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0376592 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0373373 |
| ABHD17C | abhydrolase domain containing 17C | 0.0372105 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0364586 |
| RBM6 | RNA binding motif protein 6 | 0.0359263 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0357525 |
| MYOF | myoferlin | 0.0352414 |
| NEBL | nebulette | 0.0343702 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0343427 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | 0.034168 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0335889 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0335429 |
| VEGFA | vascular endothelial growth factor A | 0.0334651 |
| MED13 | mediator complex subunit 13 | 0.0332134 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0330803 |
| TMEM165 | transmembrane protein 165 | 0.0329196 |
| YEATS2 | YEATS domain containing 2 | 0.0324029 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0323296 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0321574 |
| HLA-B | major histocompatibility complex, class I, B | 0.0318736 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0313073 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0312481 |
| LIMA1 | LIM domain and actin binding 1 | 0.0312245 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | 0.0310041 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0308759 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0308355 |
| TMPRSS4 | transmembrane protease, serine 4 | 0.0306234 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0304947 |
| HMGA2 | high mobility group AT-hook 2 | 0.0301548 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0301385 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0299065 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.0299 |
| ZNF638 | zinc finger protein 638 | 0.029857 |
| MXD1 | MAX dimerization protein 1 | 0.0297749 |
| MTDH | metadherin | 0.0297668 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.0294736 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0290367 |
| EFNA5 | ephrin-A5 | 0.0290079 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0288333 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0282421 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0280515 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0966897 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0761578 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0735612 |
| VMP1 | vacuole membrane protein 1 | -0.0632841 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.060524 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0568955 |
| GPC6 | glypican 6 | -0.0557278 |
| POTEF | POTE ankyrin domain family, member F | -0.0556682 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0535366 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0533233 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0531884 |
| SETD5 | SET domain containing 5 | -0.0519943 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0510176 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0508865 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0504069 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.049798 |
| FN1 | fibronectin 1 | -0.0484737 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0483993 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0480549 |
| RPS4X | ribosomal protein S4, X-linked | -0.047921 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.047823 |
| FTL | ferritin, light polypeptide | -0.0475953 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0467009 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0466622 |
| COPA | coatomer protein complex, subunit alpha | -0.0465361 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0463142 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0462758 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0458869 |
| TAOK3 | TAO kinase 3 | -0.0454435 |
| ARF1 | ADP-ribosylation factor 1 | -0.0440519 |
| TMEM41B | transmembrane protein 41B | -0.043304 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0429482 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0427355 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0424968 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0422994 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0420178 |
| RLF | rearranged L-myc fusion | -0.0417439 |
| CDC73 | cell division cycle 73 | -0.0415712 |
| PDE10A | phosphodiesterase 10A | -0.0412362 |
| DST | dystonin | -0.0410156 |
| AFF1 | AF4/FMR2 family, member 1 | -0.0409521 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0399579 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | -0.0397112 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0387721 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | -0.0385378 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0383962 |
| USP53 | ubiquitin specific peptidase 53 | -0.0373159 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0366885 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0364451 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0361258 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0361036 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0359774 |
| ANXA2 | annexin A2 | -0.0359593 |
| RPL31 | ribosomal protein L31 | -0.034975 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0341704 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0340089 |
| FAM13B | family with sequence similarity 13, member B | -0.0338639 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0337056 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0336166 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0332621 |
| OXSR1 | oxidative stress responsive 1 | -0.0332607 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0331195 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0327792 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0326402 |
| PRRC2C | proline-rich coiled-coil 2C | -0.032542 |
| INTS6 | integrator complex subunit 6 | -0.0318562 |
| MYL12B | myosin, light chain 12B, regulatory | -0.03152 |
| CERS6 | ceramide synthase 6 | -0.031451 |
| KIF5B | kinesin family member 5B | -0.0313053 |
| SEPTIN7 | septin 7 | -0.0312372 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | -0.0311922 |
| SRPK2 | SRSF protein kinase 2 | -0.0311028 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0306594 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0306144 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | -0.0304092 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0302172 |
| SMAD2 | SMAD family member 2 | -0.0301098 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.029496 |
| RPL26 | ribosomal protein L26 | -0.0293342 |
| RPS6 | ribosomal protein S6 | -0.0293201 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0288727 |
| DIAPH1 | diaphanous-related formin 1 | -0.0288502 |
| KLF6 | Kruppel-like factor 6 | -0.0285539 |
| OSMR | oncostatin M receptor | -0.028394 |
| RPLP1 | ribosomal protein, large, P1 | -0.0283648 |
| TENT2 | terminal nucleotidyltransferase 2 | -0.0282555 |
| ZNF292 | zinc finger protein 292 | -0.028032 |
| RPL7 | ribosomal protein L7 | -0.0278928 |
| RUNX1 | runt-related transcription factor 1 | -0.0278715 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0274396 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0271713 |
| RPS27A | ribosomal protein S27a | -0.0269716 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0269238 |
| SEC24A | SEC24 family member A | -0.0268904 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0266606 |
| HELZ | helicase with zinc finger | -0.026366 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0261849 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.026166 |
| URI1 | URI1, prefoldin-like chaperone | -0.0260438 |
| MTREX | Mtr4 exosome RNA helicase | -0.0260412 |
