| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Baicalin perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Baicalin_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MCL1 | myeloid cell leukemia 1 | 0.0723648 |
| VCL | vinculin | 0.0575904 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0538684 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.046202 |
| INTS6 | integrator complex subunit 6 | 0.0414701 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.040585 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0401803 |
| PRELID2 | PRELI domain containing 2 | 0.0397906 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0394251 |
| OSMR | oncostatin M receptor | 0.0356923 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0353757 |
| ACTN1 | actinin, alpha 1 | 0.0348213 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0346635 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0323553 |
| WWOX | WW domain containing oxidoreductase | 0.0313992 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.031292 |
| AEBP2 | AE binding protein 2 | 0.0311298 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0308166 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0303952 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0293917 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0271364 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0263133 |
| PRKCE | protein kinase C, epsilon | 0.0258456 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0248821 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0241023 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0241021 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0236428 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0232242 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0230144 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0229384 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0220844 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0220392 |
| FMNL2 | formin-like 2 | 0.0218283 |
| HOMER1 | homer scaffolding protein 1 | 0.0218266 |
| FLNA | filamin A, alpha | 0.0215339 |
| DST | dystonin | 0.0208037 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0207635 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.020673 |
| VMP1 | vacuole membrane protein 1 | 0.0203599 |
| CPNE1 | copine I | 0.0202779 |
| WNT2B | wingless-type MMTV integration site family, member 2B | 0.0201617 |
| ATXN1 | ataxin 1 | 0.0201491 |
| CAPRIN2 | caprin family member 2 | 0.0191687 |
| KRT18 | keratin 18, type I | 0.0190389 |
| LOXL2 | lysyl oxidase-like 2 | 0.0186994 |
| NEK10 | NIMA-related kinase 10 | 0.0182334 |
| RPSA | ribosomal protein SA | 0.0177196 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0175596 |
| PLEC | plectin | 0.0174795 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0174087 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0174006 |
| MACROD2 | MACRO domain containing 2 | 0.0172168 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.017196 |
| KLF6 | Kruppel-like factor 6 | 0.0171726 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0171231 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0169626 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0169386 |
| KIAA1328 | KIAA1328 | 0.0167182 |
| HMGA2 | high mobility group AT-hook 2 | 0.0166529 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0166493 |
| PCBP2 | poly(rC) binding protein 2 | 0.0163109 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0161939 |
| SMAD3 | SMAD family member 3 | 0.0160001 |
| PER1 | period circadian clock 1 | 0.0158672 |
| CUL3 | cullin 3 | 0.0158334 |
| SVIL | supervillin | 0.0156898 |
| DCAF8 | DDB1 and CUL4 associated factor 8 | 0.015547 |
| FHIT | fragile histidine triad | 0.0154694 |
| INTS1 | integrator complex subunit 1 | 0.0154475 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | 0.0154249 |
| WDR1 | WD repeat domain 1 | 0.0152291 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.0151362 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0150216 |
| RBM19 | RNA binding motif protein 19 | 0.0148968 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0148137 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0147952 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | 0.0143689 |
| PDE10A | phosphodiesterase 10A | 0.014351 |
| LDHA | lactate dehydrogenase A | 0.0141349 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | 0.014117 |
| MYO1E | myosin IE | 0.0140692 |
| MTERF1 | mitochondrial transcription termination factor 1 | 0.0137987 |
| FERMT2 | fermitin family member 2 | 0.0135978 |
| XPOT | exportin, tRNA | 0.0135924 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0134679 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.0133917 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0133125 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0132646 |
| TRIM59 | tripartite motif containing 59 | 0.0130665 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0129473 |
| TEX14 | testis expressed 14 | 0.012784 |
| USP47 | ubiquitin specific peptidase 47 | 0.0125761 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.012439 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0124261 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0122815 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.012162 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.0120253 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0120094 |
| SUMF1 | sulfatase modifying factor 1 | 0.0120086 |
| DENND1A | DENN/MADD domain containing 1A | 0.0120065 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.117176 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.112986 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0978604 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.093148 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0864758 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0735948 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0648099 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0640888 |
| RPS27 | ribosomal protein S27 | -0.0634101 |
| PTMA | prothymosin, alpha | -0.0520906 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0480907 |
| RTN4 | reticulon 4 | -0.0468685 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0460017 |
| RPS6 | ribosomal protein S6 | -0.041043 |
| GRAMD1B | GRAM domain containing 1B | -0.0404449 |
| ZFR | zinc finger RNA binding protein | -0.0400041 |
| RPS8 | ribosomal protein S8 | -0.038952 |
| RPS29 | ribosomal protein S29 | -0.0385746 |
| BBX | bobby sox homolog (Drosophila) | -0.0381842 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0372676 |
| TMSB10 | thymosin beta 10 | -0.0371154 |
| XPO1 | exportin 1 | -0.0369171 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0366566 |
| MKI67 | marker of proliferation Ki-67 | -0.0362152 |
| RPS21 | ribosomal protein S21 | -0.0362099 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0361688 |
| RPL23 | ribosomal protein L23 | -0.035877 |
| PFN1 | profilin 1 | -0.03474 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0347184 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0339071 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0336589 |
| RPLP1 | ribosomal protein, large, P1 | -0.0329083 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0326466 |
| PTK2 | protein tyrosine kinase 2 | -0.0316917 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0316528 |
| GATAD2B | GATA zinc finger domain containing 2B | -0.0310007 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0300981 |
| RAB10 | RAB10, member RAS oncogene family | -0.0299191 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0286985 |
| RPS19 | ribosomal protein S19 | -0.0285454 |
| RNF38 | ring finger protein 38 | -0.028245 |
| ADAR | adenosine deaminase, RNA-specific | -0.0279359 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0278491 |
| RPS15 | ribosomal protein S15 | -0.0278034 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0276872 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0273121 |
| KIF5B | kinesin family member 5B | -0.0272747 |
| RPL26 | ribosomal protein L26 | -0.0270979 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0270794 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0270338 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.026976 |
| SEPTIN7 | septin 7 | -0.0267396 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0266773 |
| RPL37A | ribosomal protein L37a | -0.0265809 |
| PHIP | pleckstrin homology domain interacting protein | -0.0265463 |
| GOLGA4 | golgin A4 | -0.026503 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0264997 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0264176 |
| RPL38 | ribosomal protein L38 | -0.0263002 |
| LATS2 | large tumor suppressor kinase 2 | -0.0262418 |
| TLK1 | tousled-like kinase 1 | -0.0259914 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.025938 |
| RPLP2 | ribosomal protein, large, P2 | -0.0256012 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0255657 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0252895 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0252231 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0251104 |
| MYL12B | myosin, light chain 12B, regulatory | -0.024914 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0244629 |
| RPL37 | ribosomal protein L37 | -0.0243775 |
| ZNF292 | zinc finger protein 292 | -0.0242313 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0242286 |
| WASF2 | WAS protein family, member 2 | -0.0241275 |
| RPL19 | ribosomal protein L19 | -0.02397 |
| RPL11 | ribosomal protein L11 | -0.0238499 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0237953 |
| RSF1 | remodeling and spacing factor 1 | -0.0237152 |
| TPI1 | triosephosphate isomerase 1 | -0.0236462 |
| RPL36A | ribosomal protein L36a | -0.0235316 |
| PPME1 | protein phosphatase methylesterase 1 | -0.0232359 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | -0.0232325 |
| CCND2 | cyclin D2 | -0.023144 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.023067 |
| ZNF638 | zinc finger protein 638 | -0.0229142 |
| FTL | ferritin, light polypeptide | -0.0226172 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0223963 |
| CENPF | centromere protein F, 350/400kDa | -0.0223006 |
| RPS10 | ribosomal protein S10 | -0.0221971 |
| RPL35 | ribosomal protein L35 | -0.0219508 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0219492 |
| RPL31 | ribosomal protein L31 | -0.0218961 |
| RPL12 | ribosomal protein L12 | -0.0215294 |
| IGF2 | insulin-like growth factor 2 | -0.0215283 |
| RPL32 | ribosomal protein L32 | -0.0214859 |
| TXNRD1 | thioredoxin reductase 1 | -0.0211728 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.0211513 |
| CANX | calnexin | -0.020704 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0206957 |
| MED13L | mediator complex subunit 13-like | -0.0206636 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0206454 |
