| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Baicalin perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Baicalin_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PM20D1 | peptidase M20 domain containing 1 | 0.20887 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.106591 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0861902 |
| DST | dystonin | 0.0852511 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.084416 |
| INTS6 | integrator complex subunit 6 | 0.0804192 |
| VCL | vinculin | 0.0762931 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0757688 |
| PRELID2 | PRELI domain containing 2 | 0.0598616 |
| SMAD2 | SMAD family member 2 | 0.0534472 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0517722 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0517695 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0503381 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0501189 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0500323 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0490631 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0474383 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0466204 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0423025 |
| DNER | delta/notch-like EGF repeat containing | 0.0421976 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0420681 |
| CTBP2 | C-terminal binding protein 2 | 0.0419446 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0419214 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0398147 |
| DENND1A | DENN/MADD domain containing 1A | 0.0395478 |
| FLNA | filamin A, alpha | 0.0380093 |
| FMNL2 | formin-like 2 | 0.0377258 |
| LSAMP | limbic system-associated membrane protein | 0.037344 |
| EPHA4 | EPH receptor A4 | 0.0367979 |
| PCBP2 | poly(rC) binding protein 2 | 0.0344629 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0337955 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0329127 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.032493 |
| PDE10A | phosphodiesterase 10A | 0.0319732 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0309578 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0297873 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0293459 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0286117 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | 0.0277201 |
| GPC6 | glypican 6 | 0.0272338 |
| AUTS2 | autism susceptibility candidate 2 | 0.0270486 |
| UNC5D | unc-5 homolog D (C. elegans) | 0.0266966 |
| AEBP2 | AE binding protein 2 | 0.0264628 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0261501 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0261411 |
| MARCHF1 | membrane associated ring-CH-type finger 1 | 0.0259767 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0258692 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0250179 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0245108 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0243366 |
| PTEN | phosphatase and tensin homolog | 0.0241684 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0240055 |
| RAD51B | RAD51 paralog B | 0.0238334 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.0237021 |
| MCL1 | myeloid cell leukemia 1 | 0.0236098 |
| BMP6 | bone morphogenetic protein 6 | 0.0232534 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0232297 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0231696 |
| SPAG9 | sperm associated antigen 9 | 0.0227774 |
| XYLT1 | xylosyltransferase I | 0.0227493 |
| SQSTM1 | sequestosome 1 | 0.0226997 |
| RYR2 | ryanodine receptor 2 (cardiac) | 0.0225682 |
| GLRX | glutaredoxin (thioltransferase) | 0.0224699 |
| CDH13 | cadherin 13 | 0.0224237 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0222757 |
| IRS2 | insulin receptor substrate 2 | 0.0222142 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0221376 |
| NRXN3 | neurexin 3 | 0.02177 |
| TOP1 | topoisomerase (DNA) I | 0.0217621 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0217504 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0217373 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | 0.0216707 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0215568 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0214189 |
| PGM2L1 | phosphoglucomutase 2-like 1 | 0.0213893 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0212578 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0211418 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0211111 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0208288 |
| ITPK1 | inositol-tetrakisphosphate 1-kinase | 0.0207453 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0206463 |
| COPA | coatomer protein complex, subunit alpha | 0.0205959 |
| CADM2 | cell adhesion molecule 2 | 0.0205801 |
| MAFK | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K | 0.020259 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0200718 |
| RCOR1 | REST corepressor 1 | 0.0200367 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0200086 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0199392 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0199142 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.019886 |
| HDAC4 | histone deacetylase 4 | 0.0198769 |
| ZNF644 | zinc finger protein 644 | 0.0195546 |
| DSCAM | Down syndrome cell adhesion molecule | 0.019279 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0190024 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0187983 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0183768 |
| TMSB10 | thymosin beta 10 | 0.0180041 |
| RPSA | ribosomal protein SA | 0.0179356 |
| CUX1 | cut-like homeobox 1 | 0.0177483 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0177127 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | -0.20623 |
| TXNRD1 | thioredoxin reductase 1 | -0.123461 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.114659 |
| GDA | guanine deaminase | -0.105979 |
| EFNA5 | ephrin-A5 | -0.105765 |
| ASPH | aspartate beta-hydroxylase | -0.0954344 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0899383 |
| VIM | vimentin | -0.0806006 |
| FN1 | fibronectin 1 | -0.0776515 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0769149 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0746246 |
| CD109 | CD109 molecule | -0.0745127 |
| TMX4 | thioredoxin-related transmembrane protein 4 | -0.0700096 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0699674 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0674797 |
| PCBP3 | poly(rC) binding protein 3 | -0.0631138 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0572795 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0566502 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0565399 |
| PTGR1 | prostaglandin reductase 1 | -0.0548844 |
| PYGL | phosphorylase, glycogen, liver | -0.0545614 |
| NEK7 | NIMA-related kinase 7 | -0.0529268 |
| MFF | mitochondrial fission factor | -0.0518464 |
| OSMR | oncostatin M receptor | -0.0518234 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | -0.0509646 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0504071 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0501749 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0499824 |
| SMYD3 | SET and MYND domain containing 3 | -0.049074 |
| NRCAM | neuronal cell adhesion molecule | -0.0452194 |
| RPS6 | ribosomal protein S6 | -0.0424354 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0423616 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.042246 |
| RTN4 | reticulon 4 | -0.0407538 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0403251 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.040096 |
| TNPO1 | transportin 1 | -0.0396409 |
| BMERB1 | bMERB domain containing 1 | -0.0369541 |
| CTSL | cathepsin L | -0.0364708 |
| PGK1 | phosphoglycerate kinase 1 | -0.0363689 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0350346 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0348274 |
| INHBA | inhibin, beta A | -0.0346356 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0345681 |
| GRAMD1B | GRAM domain containing 1B | -0.0332836 |
| ENAH | enabled homolog (Drosophila) | -0.0332646 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0330311 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0327824 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0317501 |
| LAMB1 | laminin, beta 1 | -0.0317257 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | -0.0311935 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0308591 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0306864 |
| CTSC | cathepsin C | -0.0304038 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -0.0302352 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0300052 |
| MKI67 | marker of proliferation Ki-67 | -0.0296788 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0295752 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0294826 |
| CENPF | centromere protein F, 350/400kDa | -0.0294272 |
| RPL36A | ribosomal protein L36a | -0.0293771 |
| AGFG1 | ArfGAP with FG repeats 1 | -0.0291374 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0288903 |
| ENO1 | enolase 1, (alpha) | -0.0287942 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0285276 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0284213 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0283468 |
| RPL12 | ribosomal protein L12 | -0.0275481 |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | -0.0274864 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0271158 |
| S100A6 | S100 calcium binding protein A6 | -0.0266126 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0264618 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0264499 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0264475 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | -0.0262795 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0257659 |
| MT2A | metallothionein 2A | -0.0253324 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0248029 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0246277 |
| CRLF2 | cytokine receptor-like factor 2 | -0.0245288 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | -0.0240378 |
| ESM1 | endothelial cell-specific molecule 1 | -0.0236473 |
| MSANTD3 | Myb/SANT-like DNA-binding domain containing 3 | -0.0232013 |
| RPS2 | ribosomal protein S2 | -0.0231298 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0230594 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0229936 |
| PALLD | palladin, cytoskeletal associated protein | -0.0228141 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0226146 |
| MYOF | myoferlin | -0.0225839 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0225494 |
| UBXN4 | UBX domain protein 4 | -0.0223702 |
| RAI1 | retinoic acid induced 1 | -0.0223582 |
| STC1 | stanniocalcin 1 | -0.0222374 |
| SRGN | serglycin | -0.0222111 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0221711 |
| KPNB1 | karyopherin (importin) beta 1 | -0.022121 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0221147 |
| SEPTIN10 | septin 10 | -0.0220098 |
| PHF20 | PHD finger protein 20 | -0.0220085 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | -0.0219808 |
