| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Baicalin perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Baicalin_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.122475 |
| FN1 | fibronectin 1 | 0.115293 |
| USP34 | ubiquitin specific peptidase 34 | 0.108039 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.100034 |
| EGFR | epidermal growth factor receptor | 0.0994847 |
| NRG1 | neuregulin 1 | 0.0944794 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0915596 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0908636 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0865738 |
| SPAG9 | sperm associated antigen 9 | 0.0856605 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0832609 |
| FAM13A | family with sequence similarity 13, member A | 0.08296 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0808317 |
| DST | dystonin | 0.0800076 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0799843 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0784736 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.0769759 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0749403 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0669925 |
| MYO6 | myosin VI | 0.0644061 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0628692 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.062524 |
| MCL1 | myeloid cell leukemia 1 | 0.0597165 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0596391 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0588493 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0564769 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0545171 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0521265 |
| SBF2 | SET binding factor 2 | 0.0517852 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0513153 |
| SLTM | SAFB-like, transcription modulator | 0.0508396 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0482033 |
| XPOT | exportin, tRNA | 0.0474977 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0472807 |
| ATXN1 | ataxin 1 | 0.046125 |
| CDH13 | cadherin 13 | 0.0454959 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0454035 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0442547 |
| GOLGA4 | golgin A4 | 0.0441514 |
| YBX3 | Y box binding protein 3 | 0.0440586 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0428589 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0424979 |
| SMYD3 | SET and MYND domain containing 3 | 0.0400877 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0389355 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0388852 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0365415 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0341433 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0325343 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0323028 |
| IGF2 | insulin-like growth factor 2 | 0.0322291 |
| SMAD3 | SMAD family member 3 | 0.0314524 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.030473 |
| ASPH | aspartate beta-hydroxylase | 0.0283845 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.02829 |
| PCBP2 | poly(rC) binding protein 2 | 0.027719 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0273821 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0271666 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.0266505 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0255515 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0251607 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0229752 |
| GPC6 | glypican 6 | 0.0220219 |
| INHBA | inhibin, beta A | 0.0219103 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0215071 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0212984 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0186179 |
| ZNF148 | zinc finger protein 148 | 0.0165984 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.016449 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0157983 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0149989 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0149166 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0139239 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0137996 |
| CANX | calnexin | 0.0137164 |
| UBXN4 | UBX domain protein 4 | 0.0128171 |
| ENO1 | enolase 1, (alpha) | 0.0125308 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.011692 |
| DTNA | dystrobrevin, alpha | 0.0115693 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0112638 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0112452 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0110241 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0107237 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0107191 |
| INTS6 | integrator complex subunit 6 | 0.0105457 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.010476 |
| STC1 | stanniocalcin 1 | 0.00975986 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.00969081 |
| RPLP1 | ribosomal protein, large, P1 | 0.00958024 |
| ANKRD12 | ankyrin repeat domain 12 | 0.00939639 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.00880183 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.00874811 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.00857515 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.00834887 |
| FMNL2 | formin-like 2 | 0.00813046 |
| HLA-B | major histocompatibility complex, class I, B | 0.00750803 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0061829 |
| MT2A | metallothionein 2A | 0.00615357 |
| TPM4 | tropomyosin 4 | 0.00567251 |
| B2M | beta-2-microglobulin | 0.00519391 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.0046927 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.330661 |
| VIM | vimentin | -0.248789 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.139056 |
| TMSB10 | thymosin beta 10 | -0.106709 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.101558 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0936299 |
| MYO1E | myosin IE | -0.0901872 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0819229 |
| FLNB | filamin B, beta | -0.0819185 |
| NF1 | neurofibromin 1 | -0.0773889 |
| RPS13 | ribosomal protein S13 | -0.0731885 |
| RPS6 | ribosomal protein S6 | -0.0679126 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0675598 |
| MYOF | myoferlin | -0.06711 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0646734 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0621272 |
| LAMA4 | laminin, alpha 4 | -0.0556162 |
| PRKCA | protein kinase C, alpha | -0.0546838 |
| RPL31 | ribosomal protein L31 | -0.0546145 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0542008 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0532167 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0509636 |
| EGR1 | early growth response 1 | -0.0501911 |
| MAP1B | microtubule-associated protein 1B | -0.0496102 |
| LDHA | lactate dehydrogenase A | -0.0469871 |
| TAF1B | TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa | -0.0451136 |
| FHIT | fragile histidine triad | -0.044925 |
| RPL15 | ribosomal protein L15 | -0.0439744 |
| ANXA2 | annexin A2 | -0.0435951 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.043438 |
| LOXL2 | lysyl oxidase-like 2 | -0.0422714 |
| RPS8 | ribosomal protein S8 | -0.0421284 |
| SP100 | SP100 nuclear antigen | -0.0415995 |
| S100A9 | S100 calcium binding protein A9 | -0.0415976 |
| RPL37A | ribosomal protein L37a | -0.041151 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0406847 |
| MAP4 | microtubule-associated protein 4 | -0.0404207 |
| PRSS23 | protease, serine, 23 | -0.0400648 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0396106 |
| NAV1 | neuron navigator 1 | -0.0386699 |
| AHNAK | AHNAK nucleoprotein | -0.0385012 |
| PRELID2 | PRELI domain containing 2 | -0.0377279 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0373998 |
| CD44 | CD44 molecule (Indian blood group) | -0.0370744 |
| RPLP0 | ribosomal protein, large, P0 | -0.0351005 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0348486 |
| NDRG1 | N-myc downstream regulated 1 | -0.0338432 |
| HMGA2 | high mobility group AT-hook 2 | -0.0333028 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.032646 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0321843 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.031702 |
| PGK1 | phosphoglycerate kinase 1 | -0.0314742 |
| RPL37 | ribosomal protein L37 | -0.0310888 |
| TOR1AIP2 | torsin A interacting protein 2 | -0.0304089 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0300131 |
| PDE10A | phosphodiesterase 10A | -0.0296916 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.028732 |
| SETD5 | SET domain containing 5 | -0.0282012 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.028113 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0278305 |
| RPL11 | ribosomal protein L11 | -0.0277551 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0274436 |
| OSMR | oncostatin M receptor | -0.0272192 |
| RPL23 | ribosomal protein L23 | -0.0269645 |
| RAD51B | RAD51 paralog B | -0.0253055 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0247687 |
| CCNI | cyclin I | -0.024066 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0238886 |
| PTMA | prothymosin, alpha | -0.0226697 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0224029 |
| UBC | ubiquitin C | -0.0220448 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.022007 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0211742 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.019662 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0195591 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0189717 |
| PKM | pyruvate kinase, muscle | -0.0189318 |
| EFNA5 | ephrin-A5 | -0.0181057 |
| PTK2 | protein tyrosine kinase 2 | -0.0163952 |
| JMJD1C | jumonji domain containing 1C | -0.0161019 |
| CDK13 | cyclin-dependent kinase 13 | -0.0148765 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.014723 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0146837 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0142184 |
| BPTF | bromodomain PHD finger transcription factor | -0.0134185 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0131856 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0131157 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0129532 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0125511 |
| RUNX1 | runt-related transcription factor 1 | -0.0123239 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0117447 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0105199 |
| RPL35A | ribosomal protein L35a | -0.00909914 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0087078 |
| CALU | calumenin | -0.00867737 |
| TXNRD1 | thioredoxin reductase 1 | -0.00834282 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.00815864 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.00749826 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.00719263 |
| SVIL | supervillin | -0.0066943 |
